TCR repertoire shaping of naïve T cell subsets in human ontogeny. [PDF]
Myshkin MY +14 more
europepmc +1 more source
Advancing In Vivo Chimeric Antigen Receptor T‐Cell Engineering to Accelerate Clinical Translation
In vivo CAR‐T cell generation directly engineers endogenous T cells using pre‐manufactured gene delivery vectors that target T cells and deliver CAR‐encoding genetic material. The resulting CAR‐T cells expand in vivo and mediate antigen‐specific cytotoxicity.
Zhenxin Bai +6 more
wiley +1 more source
Naïve adaptive immune receptor repertoires in celiac disease assessed by machine learning; impact of the HLA-DQ2.5 allotype on the TCR repertoire. [PDF]
Officer A +6 more
europepmc +1 more source
Role of Extracellular Vesicles in Shaping Immune Responses in the Lymph Node Microenvironment
Functional alliances of stromal, innate and adaptive immune cells in EV immunity in the lymph node. EV reflect the phenotype of their mother cell and cluster material from their surroundings. In the lymph node, EV preserve valuable context information between multiple cellular effectors to coordinate immunity in adaption to change.
Alicia Charrier +4 more
wiley +1 more source
A TCR meghatározó szerepe a társadalmi felelősségvállalásban
TCR reklámok elemzése, illetve hogy hogyan hatnak eszközeik a cégek, szervezetek és magánemberek felelős gondolkodására. A reklámok által felelősebben fogunk gondolkodni a Világunkról?
Ábel, Nikolett
core
Flow Cytometric Analysis of TCR V beta Repertoire in Patients with 22q11.2 Deletion Syndrome
In 22q11.2 deletion patients, the normal decrease in T lymphocyte counts after 1-2 years is blunted such that relatively T lymphocyte numbers increase over early childhood, probably via post-thymic expansion of peripheral lymphocytes. This may leave less
Spickett GP +3 more
core +2 more sources
Immune dysregulation and exhaustion in EBV- associated hemophagocytic lymphohistiocytosis: insights from single-cell transcriptomics and TCR repertoire analysis. [PDF]
Luo X +9 more
europepmc +1 more source
Features of the TCR repertoire associate with patients' clinical and molecular characteristics in acute myeloid leukemia. [PDF]
Pospiech M +6 more
europepmc +1 more source
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo +2 more
wiley +1 more source
TCR Repertoire Analysis Unveils the Link Between Kawasaki Disease and Viral Infection. [PDF]
Geng Z +8 more
europepmc +1 more source

