Results 171 to 180 of about 58,781 (291)

C082 | T-CELL RECEPTOR-VΒ REPERTOIRE FLOW CYTOMETRY ANALYSIS SHOWED ABSOLUTE CONCORDANCE WITH MOLECULAR ANALYSIS OF TCR GENE REARRANGEMENT IN THE DIAGNOSIS OF T-CELL LYMPHOPROLIFERATIVE DISORDER: OBSERVATIONAL STUDY FROM A SINGLE CENTER EXPERIENCE.

Haematologica
Background: Clonality assessment is critical to differentiate between reactive and pathological T- cell lymphocytosis, and it usually relies on molecular analysis of T-Cell Receptor (TCR) gene rearrangement, which is considered the gold standard assay ...
M. Antonacci, J. Micozzi, A. Costa, A. Laganà, M.L. Milani, S. Intoppa, V. Bellomarino, M.G. Nardacci, M. Biglietto, S. Imperatore, M.L. Bisegna, M. Martelli, I. Della Starza, M.S. De Propris   +13 more
doaj  

The Use of HLA A2.1/p53 Peptide Tetramers to Visualize the Impact of Self Tolerance on the TCR Repertoire [PDF]

, 2000
Javier Hernández, Peter P. Lee, Mark M. Davis, Linda A. Sherman   +3 more
openalex   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Molecular defects in TCRBV genes preclude thymic selection and limit the expressed TCR repertoire [PDF]

, 1996
Jeffrey R. Currier, Maryam Yassai, M.A. Robinson, Jack Gorski   +3 more
openalex   +1 more source

Activated immune cells present a lung interstitial‐to‐airway/alveolar cross‐compartment sharing pattern in severe pneumonia

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
The interstitial‐to‐airway cross‐compartment sharing pattern of activated immune cells provides new insights for severe pneumonia. Macrophages could amplify local immune response by recruiting specific activated immune cells via CXCL10–CXCR3 signalling into airway, while other immune cells reside with limited inflammatory activity.
Yuean Zhao, Linjing Gong, He Yu, Sifan Zhang, Guanglei Yang, Chaoyang Wang, Weiya Wang, Xuyu Cai, Ye Wang   +8 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

CD8 T Cell Sensing of Type I Interferon Impacts Anergy

European Journal of Immunology, Volume 56, Issue 5, May 2026.
Basal IFN‐I acts as a rheostat to fine‐tune CD8 T cell anergy. The presence of IFN‐I induces a less deep anergic state characterised by greater expansion, residual effector function and plasticity. This favours the accumulation of autoreactive T cells that retain the potential to break tolerance rather than undergoing deletion.
Anne S. Haefke, Hanna Gröber, Ioana Sandu, Vanessa Skipness, Nikos Pantouloufos, Fabienne Gräbnitz, Marie‐Elen Tuchel, Nathan Zangger, Dominique Stark, Marvin Kříž, Carmine Cristinzio, Hanspeter Pircher, Roman Spörri, Isaak Quast, Annette Oxenius   +14 more
wiley   +1 more source

TCR β CDR3 Repertoire Signatures in Paired PBMC and BALF From Children With Mycoplasma pneumoniae Pneumonia

Xinzhu Liu
openalex   +2 more sources

TCR Repertoire Analysis Reveals Public Motifs with High Probability for Allergen Epitope Specificity [PDF]

, 2019
Neal P. Smith, Bert Ruiter, Navneet K. Virk Hundal, Huong Tang, Yamini V. Virkud, Sarita U. Patil, Wayne G. Shreffler   +6 more
openalex   +1 more source

SYK Signalling in NLRP3 Inflammasome‐Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG

European Journal of Immunology, Volume 56, Issue 5, May 2026.
IC‐mediated inflammatory response—the NLRP3 inflammasome activation, cytokine secretion, and antigen presentation depend on SYK signalling pathways in primary murine microglia. ABSTRACT Viral infections might trigger systemic inflammatory responses characterised by inflammasome activation and cytokine release, driven by immune complex (IC) formation ...
Kristina Mašalaitė, Milda Norkienė, Aurelija Žvirblienė, Asta Lučiūnaitė   +3 more
wiley   +1 more source