Results 151 to 160 of about 206,427 (253)
Adaptive Immunity in Marsupials
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 9, Page 913-932, November 2026.Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol +2 more
wiley +1 more source
Evaluated and implemented SOPs. SOPs for TCR repertoire. Samples used for generating data to develop the tools and validate the software: melanoma, colorectal cancer, and ovarian cancer.
openaire +1 more source
Multiple Sclerosis and Viruses: « Liaisons Dangereuses »
Reviews in Medical Virology, Volume 36, Issue 6, November 2026.ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina +11 more
wiley +1 more source
Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance
Immunology, Volume 179, Issue 3, Page 337-349, November 2026.Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos +5 more
wiley +1 more source
Immunology, Volume 179, Issue 3, Page 486-515, November 2026.In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque +11 more
wiley +1 more source
Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells.
, 2020 Tissue homeostasis is critically dependent on the function of tissue-resident lymphocytes, including lipid-reactive invariant natural killer T (iNKT) cells.
Gurdyal S Besra (8348871) +9 more
core
TCR Repertoire Analysis During Therapeutic Interventions in Liver Diseases Using Next-Generation Sequencing [PDF]
Background and Aim The T cell receptor (TCR) can recognize a vast number of antigens and is closely associated with the pathogenesis of various diseases including autoimmune diseases and malignancies.
村岡, 優 +40 more
core +1 more source
Liver International, Volume 46, Issue 11, November 2026.ABSTRACT Background and Aims Autoimmune hepatitis is an immune‐mediated liver disease characterized by chronic inflammation and progressive fibrosis. Tissue‐resident memory T cells mediate organ‐specific immunity, but their role in autoimmune hepatitis remains poorly understood.
Victoria Stary +8 more
wiley +1 more source
An innovative and affordable quantitative assessment of human TCR repertoire [PDF]
EBioMedicine, 2020 Roberta Amoriello, Clara Ballerini
openaire +3 more sources
Investigating CD8 T Cell Exhaustion in Chronic LCMV Infection by Flow Cytometry
Current Protocols, Volume 6, Issue 10, October 2026.Abstract CD8 T cells and the process of T cell exhaustion are central topics in both basic immunology and translational research, including clinical applications. Here, we provide a comprehensive, step‐by‐step guide to investigate CD8 T cells in murine in vivo lymphocytic choriomeningitis virus (LCMV) infection models.
Dominique Stark +5 more
wiley +1 more source