Results 131 to 140 of about 206,427 (253)
Cell Proliferation, EarlyView.Schematic diagram for the experimental design for adaptome immune repertoire analysing Dampness ZHENG across Psoriasis, Rheumatoid Arthritis and Ulcerative Colitis. ABSTRACT Autoimmune diseases, including psoriasis (Ps), rheumatoid arthritis (RA) and ulcerative colitis (UC), pose significant health burdens worldwide.
Lipeng Tang +21 more
wiley +1 more source
Breast Cancer ResearchSequencing of the T-cell receptor (TCR) repertoire can reflect immune status and monitor treatment responses. Here, we aimed to characterize the TCRβ repertoire and its correlation with clinical and prognostic significance in breast cancer.
Ling-Ming Tseng +13 more
doaj +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley +1 more source
ICSH Guidance on Bone Marrow Examination and Reporting
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber +6 more
wiley +1 more source
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Immunology &Cell Biology, EarlyView.Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
Immunology, EarlyView.Activated T‐cells instigate signalling events leading to the activation of transcription factors, which in turn, act on the nucleus to produce cytokines. We postulate that c‐fos is one of these transcription factors which upregulates the choline acetyltransferase gene responsible for synthesising acetylcholine (ACh).
Jarita Lay, Nicholas Manolios
wiley +1 more source
Factors affecting TCR-repertoire diversity
Immunology Today, 1994 Wedderburn, L, Bowness, P
openaire +2 more sources
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Deciphering TCR repertoire diversity by RepSeq data modelinig
, 2016 Les lymphocytes T (LT) sont des acteurs-clés du système immunitaire, un système complexe et dynamique évoluant au cours de la vie de l'organisme. On appelle " répertoire lymphocytaire ", une collection de lymphocytes partageant un même phénotype, une ...
Chaara, Wahiba
core
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source