Results 161 to 170 of about 34,505 (262)

RELATION ENTRE LE REPERTOIRE TCR SELECTIONNE PAR UN ANTIGENE IN VIVO ET LE REPERTOIRE PRE-IMMUN CORRESPONDANT

, 2000
LA FREQUENCE DES PRECURSEURS T SPECIFIQUES D'UN ANTIGENE (AG) DONNE ETANT BASSE, IL EST DIFFICILE D'ANALYSER LE REPERTOIRE PRE-IMMUN SPECIFIQUE D'UN AG ET DE DETERMINER SA RELATION AVEC LE REPERTOIRE SELECTIONNE AU COURS D'UN REPONSE IMMUNITAIRE.
ATTUIL, VALERIE, MARYANSKI, JANET
core  

Immunogenic Cell Death: Unlocking New Frontiers in Cancer Immunotherapy

Cancer Innovation, Volume 5, Issue 3, June 2026.
Immunogenic cell death ICD is a specific type of stress‐induced cell death that results in adaptive immune response and generating an immunological memory. The development of strategies that induce ICD are considered highly effective in the treatment of cancer within the bounds of immunotherapy.
Katherine Yaacoub
wiley   +1 more source

Features of the TCR repertoire associate with patients' clinical and molecular characteristics in acute myeloid leukemia. [PDF]

Front Immunol, 2023
Pospiech M, Tamizharasan M, Wei YC, Kumar AMS, Lou M, Milstein J, Alachkar H.   +6 more
europepmc   +1 more source

The Steroidal Profile Modulates Adaptive Immune Response and Prognosis in Adrenocortical Carcinoma: Analysis of TCR and BCR Repertoires

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Adrenocortical carcinoma (ACC) is a rare and aggressive malignant neoplasm with limited therapeutic options and an often poor prognosis. A deeper understanding of its interaction with the immune system is essential for the advancement of personalized treatment strategies, particularly in light of the tumor heterogeneity of hormone production ...
Jean Silva de Souza Resende, Igor Samesima Giner, João Carlos Degraf Muzzi, José Alexandre Marzagão Barbuto, Enzo Lalli, Mauro Antônio Alves Castro, Bonald Cavalcante de Figueiredo   +6 more
wiley   +1 more source

SOP for TCR repertoire

Evaluated and implemented SOPs. SOPs for TCR repertoire. Samples used for generating data to develop the tools and validate the software: melanoma, colorectal cancer, and ovarian cancer.
openaire   +1 more source

Immunotherapy 3.0: Breakthroughs Steering the Next Generation of Cancer Control

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Hematologic disorders, including sickle cell disease, anemias, hemoglobinopathies, leukemias, lymphomas, and bleeding disorders, constitute a substantial and growing burden of morbidity and mortality across Africa. Structural health system constraints—limited diagnostic capacity, shortages of trained hematology specialists ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq. [PDF]

Sci Rep, 2023
Heimli M, Tennebø Flåm S, Sagsveen Hjorthaug H, Bjørnstad PM, Chernigovskaya M, Le QK, Tekpli X, Greiff V, Lie BA.   +8 more
europepmc   +1 more source

Single‐cell and repertoire profiling reveals immune remodelling in paediatric upper airway: insights from adenoid hypertrophy

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
Single‐cell and paired V(D)J profiling show that paediatric adenoid hypertrophy features expanded proliferative germinal‐centre B cells with impaired maturation. Abstract Objectives To characterise the immune cellular landscape and paired B‐cell and T‐cell receptor repertoires of hypertrophic adenoids in children with obstructive sleep apnoea.
Chao Wang, Yufei Pan, Xiao Han, Kai Sun, Jing Li, Yuanyuan Lu, Zhenkun Yu   +6 more
wiley   +1 more source

Inducible CRISPR/Cas systems in precision oncology: Current applications and future perspectives

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Inducible CRISPR/Cas systems enable spatiotemporal genome editing in precision oncology. Chemical, optical, physical, and microenvironmental stimuli provide distinct control strategies. Conditional activation may reduce off‐target exposure and basal nuclease activity.
Ziliang Ding, Yukun Wei, Yong Han, Pengfei Gu   +3 more
wiley   +1 more source

TCR repertoire shaping of naïve T cell subsets in human ontogeny. [PDF]

Front Immunol
Myshkin MY, Leyn SA, Egorov ES, Shelyakin PV, Staroverov DB, Shagina IA, Kan NE, Lupyr KR, Barsova EV, Dzyubinskaya EV, Ventura-Carmenate Y, Tyutyunnik VL, Rebrikov DV, Chudakov DM, Britanova OV.   +14 more
europepmc   +1 more source