Results 51 to 60 of about 95,928 (301)

A Simplified TDT Sensor for Wire Driven Joint

Journal of Robotics and Mechatronics, 1993
A simple torque sensor for tendon-driven manipulators is proposed. The finger joint torque around a drive pulley is proportional to the.difference in tension between the two ends of the pulley. By using a coupling mechanism between tendons, this difference in tension can be measured directly, without sensing individual tendon tensions.
Imamura, Nobuaki, Yoshinari, Satoshi, Kaneko, Makoto   +2 more
openaire   +2 more sources

Áudio Descrição na Televisão Digital Terrestre (TDT)

, 2021
A Televisão Digital Terrestre (TDT), aliada à utilização de Set-Top Boxes (STB), permite aos telespectadores a utilização de funcionalidades e serviços avançados que o sistema de teledifusão convencional não consegue suportar.
Almeida, Ana Margarida, Abreu, Jorge Ferraz de, Oliveira, Rita   +2 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

The SPA motif in UbcH5a is essential for binding to TdT and for TdT ubiquitylation.

, 2012
(A) Amino acid sequence alignment of E2s. The catalytic cysteine is indicated in boldface; the SPA motif is indicated by the gray background. UbcH5, UbcH6, and UbcH13, which bind to TdT, have a SPA motif in loop 7. (B) Mutation of the SPA motif in UbcH5a
Takuro Matsumoto (152830), Tomoyoshi Kato (152813), Sachiko Ando (152827), So Maezawa (152806), Kotaro Koiwai (152844), Osamu Koiwai (152848), Takahide Hayano (152836), Masahiro Suzuki (152839), Yoshihiro Nishiyama (152821), Rie Fukushima (152809), Toyofumi Matsushita (152811), Yoshiki Takagaki (152817), Kousuke Kouda (152833)   +12 more
core   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

UbcH5a or UbcH6 binds to TdT in vivo.

, 2012
(A) Immunoprecipitation using Myc-TdT as the bait. 293 T cells were co-transfected with expression vectors encoding Flag-UbcH5a (lanes 1 and 3) and Myc-TdT (lanes 2 and 3).
Takuro Matsumoto (152830), Tomoyoshi Kato (152813), Sachiko Ando (152827), So Maezawa (152806), Kotaro Koiwai (152844), Osamu Koiwai (152848), Takahide Hayano (152836), Masahiro Suzuki (152839), Yoshihiro Nishiyama (152821), Rie Fukushima (152809), Toyofumi Matsushita (152811), Yoshiki Takagaki (152817), Kousuke Kouda (152833)   +12 more
core   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

TdT-deficient T cells undergo more efficient positive selection.

(A) Mixed BM chimeras possessing WT and TdT KO cells (reconstitution of irradiated mice with 1:1 ratio of BM cells) were generated, and the thymus was harvested 6 weeks after irradiation for each mouse.
Anmar Khadra (221668), Dakota Rogers (5632442), Jérémy Postat (17889640), Geneviève Perreault (17889637), Dhanesh Patel (12983882), Hassan Jamaleddine (17889634), Judith N. Mandl (17889643)   +6 more
core   +1 more source

TdT ubiquitylation inhibits its nucleotidyltransferase activity.

, 2012
(A) Ubiquitylation of TdT does not effect its DNA-binding property. His-TdT (180 ng) was incubated in the reaction in vitro ubiquitylation mixture with (lane 3) or without (lane 2) biotinylated ssDNA coupled to streptavidin–agarose.
Takuro Matsumoto (152830), Tomoyoshi Kato (152813), Sachiko Ando (152827), So Maezawa (152806), Kotaro Koiwai (152844), Osamu Koiwai (152848), Takahide Hayano (152836), Masahiro Suzuki (152839), Yoshihiro Nishiyama (152821), Rie Fukushima (152809), Toyofumi Matsushita (152811), Yoshiki Takagaki (152817), Kousuke Kouda (152833)   +12 more
core   +1 more source