Results 61 to 70 of about 15,110,620 (315)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Examining the Reliability and Validity of a Turkish Version of the Community of Inquiry Survey

open access: yesOnline Learning, 2018
The aim of this study was to describe the validity and reliability of a Turkish language version of the CoI survey developed by Arbaugh et al. (2008). Adaptation of the survey into Turkish is described.
Yusuf Ziya OLPAK, Ebru KILIÇ ÇAKMAK
doaj   +1 more source

Facilitation Strategies in Online Group Work from the Perspective of Community of Inquiry

open access: yesJurnal Teknologi Pendidikan, 2022
The COVID-19 pandemic has resulted in disruptions in a number of aspects of our lives, including in language education. Teaching and learning are now done remotely using various online learning platforms and educational technologies.
Monica Ella Harendita   +1 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Center for Teaching Excellence Spring 2021 Newsletter

open access: yes, 2021
Inside this issue: Teaching in the Post-Pandemic Classroom -- CTE Blog: Reflections on Teaching & Learning -- Spring 2021 Reading Group -- Building Pedagogical Capacity: Collaborative Events AY 2020 ...
Center for Teaching Excellence
core  

Teaching and social presence in online foreign language teaching

open access: yes, 2020
This paper examines and reports on ways of promoting teaching presence in foreign language online learning environments in Finland and Spain. ‘Teaching presence’ refers to all the tools and resources teachers use during online courses to deliver teaching, guidance and feedback, or
Pasi Puranen, Ruby Vurdien
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Teaching Presence in Online Gamified Education for Sustainability Learning

open access: yesSustainability, 2020
Gamification in education refers to the introduction of game elements in the design of learning processes. Our gamification approach was based on the self-determination theory.
Siti Nur Diyana Mahmud   +2 more
semanticscholar   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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