Results 91 to 100 of about 1,915,493 (292)

Research on the Model of Technological Pedagogical Content Knowledge of Teachers (TPACK)

open access: yesZhishi guanli luntan, 2019
[Purpose/significance] TPACK framework doesn’t describe the level of knowledge, and the generation and transformation process of knowledge. This paper constructed a TCP teacher knowledge system model to describe the TPACK structure of teachers more ...
Zhan Rui
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Specialized Educational Attendance and contributing technologies for deaf learning / Atendimento Educacional Especializado e as tecnologias contribuindo para a aprendizagem dos surdos

open access: yesDiversitas Journal, 2017
Inclusive education has been discussed and establishing itself internationally and laws and regulations outlining ways for us to have a quality education for all, even for those in need of Educational Service Specialist (ESA).
Rose Madalena Pereira da Silva
doaj   +1 more source

Technology Push, Demand Pull And The Shaping Of Technological Paradigms - Patterns In The Development Of Computing Technology [PDF]

open access: yes
An assumption generally subscribed in evolutionary economics is thatnew technological paradigms arise from advances is science anddevelopments in technological knowledge.
Dolfsma, W.A., Ende, J.C.M. van den
core   +1 more source

Education for sustainable development within textile technology: a case study of two schools [PDF]

open access: yes, 2015
Design and technology (D&T) requires teachers to continually update their knowledge and skills, with regard to new technologies, appropriate to the needs of the time (Design and Technology Association, 2011).
Davies, S, Hail, Y
core  

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

When Micro Shapes the Meso: Learning Networks in a Chilean Wine Cluster [PDF]

open access: yes
Most analyses of the relationship between spatial clustering and the technological learning of firms have emphasised the influence of the former on the latter, and have focused on intra-cluster learning as the driver of innovative performance. This paper
Elisa Giuliani, Martin Bell
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy