Results 101 to 110 of about 9,146,795 (310)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Communities, Knowledge, and Innovation: Indian Immigrants in the US Semiconductor Industry [PDF]

open access: yes
This paper investigates the influence of technological, geographic, and ethnic communities on the innovativeness of Indian inventors. We study Indian inventors in the semiconductor industry in the US and examine their patenting profiles between 1975 and ...
Paul Almeida, Anupama Phene, Sali Li
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Doctors’ perception on the ethical use of AI-enabled clinical decision support systems for antibiotic prescribing recommendations in Singapore

open access: yesFrontiers in Public Health
ObjectivesThe increased utilization of Artificial intelligence (AI) in healthcare changes practice and introduces ethical implications for AI adoption in medicine.
Zhilian Huang   +6 more
doaj   +1 more source

Technological Opportunities, Absorptive Capacities, and Innovation [PDF]

open access: yes
The aim of this paper is to analyze the effects of technological opportunities on the innovation activities of firms, depending on their absorptive capacities.
Wolfgang Becker, Juergen Peters
core  

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Recombinant Knowledge and Growth: The Case of ICTs [PDF]

open access: yes
The economics of recombinant knowledge is a promising field of investigation. New technological systems emerge when strong cores of complementary knowledge consolidate and feed an array of coherent applications and implementations.
Francesco Quatraro   +2 more
core  

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

The role of technological gatekeepers in the growth of industrial clusters: Evidence from Chile [PDF]

open access: yes
Industrial clusters are often associated with innovative success. However, there is very little research on what types of organizational models apply to clusters as they grow, to facilitate upgrading and innovation Ð and especially in emerging/developing
Elisa Giuliani
core  

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