Results 91 to 100 of about 9,146,795 (310)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Technological knowledge and the theory of the firm: The role of idiosyncratic factors in the quest for the economics of distinctive competences [PDF]

open access: yes
This paper elaborates a theory of the firm that combines the intuitions of Edith Penrose with the analysis of localized technological knowledge. The analysis of the characteristics of knowledge indivisibility and of idiosyncratic factors pIay a key role ...
Antonelli Cristiano
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Technological innovation persistence : Literature survey and exploration of the role of organizational innovation [PDF]

open access: yes
In this paper, we will review the literature on technological innovation persistence and provide a general theoretical framework to analyze the main determinants of this innovative behavior.
Christian Le Bas   +2 more
core   +2 more sources

Absorptive capacity in technological learning in clean development mechanism projects [PDF]

open access: yes
Technology transfer in Clean Development Mechanism (CDM) projects of the Kyoto Protocol has become one of the important issues addressed both in policy agenda and by academic scholars.
Doranova, Asel   +2 more
core  

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Technological knowledge as an essential facility [PDF]

open access: yesJournal of Evolutionary Economics, 2007
The economics of regulation has articulated the notions of essential facility and mandated interconnection. Their application to the governance of technological knowledge can be fruitful especially when implemented by the adoption of a compensatory liability rule and the parallel reduction in the exclusivity of patents. Because knowledge is at the same
openaire   +2 more sources

Technological opportunity, long-run growth and convergence [PDF]

open access: yes
We derive an R&D-based semi-endogenous growth model where technological progress depends on the available amount of technological opportunity. Incremental innovations provide direct increases in the knowledge stock but they reduce technological ...
Jakub, GROWIEC, Ingmar, SCHUMACHER
core  

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