Results 51 to 60 of about 333,537 (267)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Effect of incorporation of candelilla wax oleogel on the structural properties of cake-type bread

Tecnociencia Chihuahua
The negative health effects associated with foods containing saturated and trans fats have prompted the search for healthier alternatives that preserve both sensory and technological quality.
Gilda Avendaño Vásquez, Bryan Ochoa Martínez, Karen Aylin Vargas García, Juan René González Romero, Miguel Angel García Muñoz, Elizabeth del Carmen Varela Santos   +5 more
doaj   +1 more source

Comparison of nutritional and technological quality of winter wheat (Triticum aestivum L.) and hybrid wheat (Triticum aestivum L. x Triticum spelta L.) [PDF]

Journal of Central European Agriculture, 2018
Wheat is one of the most important food crop in the world. Gluten proteins represent major protein fraction of the grain and are responsible for unique properties of the dough.
Dana RAJNINCOVÁ, Zdenka GÁLOVÁ, Lenka PETROVIČOVÁ, Milan CHŇAPEK   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Development and Quality Assessment of Fat-Reduced Turkish Fermented Sausage (Sucuk) Formulated with Functional Lemon Fiber

Polish Journal of Food and Nutrition Sciences
This study aimed to produce Turkish fermented sausage (sucuk) with a reduced fat content and to minimize the quality defects typically associated with fat reduction by incorporating lemon fiber into the formulation.
Zeki Gürler, Teslime Ekiz Ünsal
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Straw Retention Enables the Yield and Quality Benefits of Reduced Tillage in Winter Wheat and Spring Barley: A Long-Term Study

Agriculture
Agronomic practices can modify cereal grain chemical composition and processing performance. Long-term evidence linking agricultural management with functionality-related quality remains limited, especially in terms of combined tillage x crop residue ...
Aušra Sinkevičienė, Vaclovas Bogužas, Vaida Steponavičienė, Alfredas Sinkevičius, Aušra Marcinkevičienė, Marta Wyzińska, Adam Kleofas Berbeć, Rasa Kimbirauskienė   +7 more
doaj   +1 more source

The Influence of Mobile Technologies on the Quality of Sleep

Journal of Biomedical Physics and Engineering
The extensive usage of mobile phones across all age brackets, including children and teenagers, leads to significant exposure to Radiofrequency Electromagnetic Fields (RF-EMF). This exposure raises concerns about potential adverse effects on sleep. The current study aimed to explore the influence of mobile phone-emitted RF-EMFs on the duration and ...
Slezáková, Zuzana, Baláž, Jozef, Wimmerová, Soňa, Valachovičová, Martina   +3 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source