Results 161 to 170 of about 113,797 (252)

Nanoparticle-based colorimetric biosensor for the detection of telomerase activity based on the peroxidase-mimicking activity of nanogold. [PDF]

RSC Adv
Hoang Uyen LT, Cam Duyen VT, Truong PL.
europepmc   +1 more source

Assessment of pTERT Subtypes of Glioblastoma by Quantitative FLAIR Analysis Based on Fusing MRI Images

Brain and Behavior, Volume 16, Issue 3, March 2026.
Assessment of pTERT subtypes of glioblastoma by quantitative FLAIR analysis based on fusing MRI images, Participants, Methods, Results, Glioblastoma patients, Segmented to 3 subregions Investigated the significant metrics of subregions and other clinical‐imaging factors Prediction models of pTERT Tested in validation cohorts pTERTm, pTERTw, Conclusion:
Bocong Gao, Guanmin Quan, Yawu Liu, Tao Yuan   +3 more
wiley   +1 more source

Telomerase Activity in Melanoma: Impact on Cancer Cell Proliferation Kinetics, Tumor Progression, and Clinical Therapeutic Strategies-A Scoping Review. [PDF]

Curr Oncol
Alqaisi O, Storme G, Dennis A, Dibas M, Sijarina L, Grabovci L, Al-Zghoul S, Yu E, Tai P.   +8 more
europepmc   +1 more source

A Critical Analysis of the Impact of Etoposide as a Topoisomerase II Inhibitor in Cervical Cancer Treatment: A Review

Cancer Medicine, Volume 15, Issue 3, March 2026.
Etoposide mediated topoisomerase II inhibition in Cervical Cancer. ABSTRACT Background Etoposide is a semisynthetic derivative of podophyllotoxin and an FDA‐approved topoisomerase II inhibitor that induces DNA strand breaks leading to cancer cell death.
Nikitha Kotian, Yashaswini Reddy, Padmini Pai, Babitha Kampa Sundara   +3 more
wiley   +1 more source

CRISPR Assays for Protein Detection

Chemistry–Methods, Volume 6, Issue 3, March 2026.
This review summarizes recent advances in CRISPR–Cas–based strategies for protein detection. Particular focus is placed on recognition element–based approaches, in which antibodies, aptamers, or DNAzymes convert protein binding into CRISPR‐readable nucleic acid signals, and activity‐based strategies that exploit intrinsic protein functions to trigger ...
Luca Capelli, Elena Spezzani, Dharshini Raghavan, Chiara Micucci, Alessandra Zanut, Alessandro Bertucci   +5 more
wiley   +1 more source

Arsenic trioxide allosterically inhibits human telomerase, validated by in-silico and in-vitro cancer and non cancer cell lines. [PDF]

Sci Rep
Chaudhary A, Kumar R, Kumari K, Singh VK, Ojha KK, Kumar N, Prakash K, Ola MS, Haque R.   +8 more
europepmc   +1 more source

Genomic Integrity in Gull Chicks Predicts Colony Departure and Postfledging Movements

Ecology and Evolution, Volume 16, Issue 3, March 2026.
We integrated molecular biomarkers with high‐resolution GPS tracking to study key behavioral decisions during the transition to independence in a long‐lived colonial seabird. We found that juveniles with shorter telomeres and higher DNA damage leave the colony earlier, revealing a link between physiological state and movement ecology.
Alberto Velando, Susana Cortés‐Manzaneque, Sin‐Yeon Kim   +2 more
wiley   +1 more source

Structures of nucleotide-bound human telomerase at several steps of its telomeric DNA repeat addition cycle. [PDF]

Nat Commun
Balch S, Franco-Echevarría E, Ghanim GE, Kretsch RC, Das R, Nguyen THD.   +5 more
europepmc   +1 more source

Telomerase [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Move beyond free radical theory of aging

iMetaOmics, Volume 3, Issue 1, March 2026.
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley   +1 more source