Higher exposure to PM2.5 and PM10 accelerates biological aging, a process significantly mitigated by adherence to sustainable, plant‐based dietary patterns. These results underscore the potential of sustainable diets to counteract the detrimental effects of air pollution on healthy aging and longevity.
Rui Qiang Li +11 more
wiley +1 more source
La protein binding to telomerase RNA supports an evolutionary relationship between plant and ciliate telomerase pathways. [PDF]
Jenner L +8 more
europepmc +1 more source
Ageing Through the Looking‐Glass: The Different Flavours of Clonal Haematopoiesis
Different forms of CH share common germline and environmental risk factors and have overlapping prevalence and disease associations, suggesting common underlying ageing processes. We explore intersections of different forms of CH, clinical implications of these, and how this enhances our understanding of the biology of ageing.
Jasmine Singh +4 more
wiley +1 more source
Prognostic stratification in hepatocellular carcinoma using a telomerase-related lncRNA signature derived from TCGA database. [PDF]
Yang R +5 more
europepmc +1 more source
DNA Methylation Signatures of Cellular Senescence Are Not Reversed by Senolytic Treatment
We found very little overlap between CpGs that were correlated with in vitro senescence, chronological age, and mortality. While we were able to train epigenetic clocks with CpGs that accelerated with cellular senescence, these clocks did not decelerate with Senolytic treatment. ABSTRACT Epigenetic clocks are commonly used aging biomarkers based on DNA
Jessica Kasamoto +7 more
wiley +1 more source
ABSTRACT One barrier to mental health and a common focus of psychotherapy is the tendency to identify with relentless, often self‐critical thinking that searches for faults, becomes easily distracted, and pulls individuals away from the present moment.
Barbara Carter
wiley +1 more source
Global research trends and prospects related to telomerase within breast cancer: a bibliometric and visual analysis. [PDF]
Qu L, Ding S, Long Q, Yi W.
europepmc +1 more source
Rare Germline Variants in CDKN2A‐Negative Children and Adolescents With Cutaneous Melanoma
Individuals with childhood and adolescent melanoma carry inherited mutations in shelterin complex genes, pigmentation genes and MBD4, but have fewer MC1R R‐alleles than adults with melanoma. Created with BioRender.com. ABSTRACT Cutaneous melanoma is a complex disease influenced by both environmental and genetic factors. Inherited susceptibility plays a
Peter A. Johansson +10 more
wiley +1 more source
Pancreatic Cancer Stem Cells Co-Expressing SOX2, OCT4, and TERThigh Represent an Aggressive Subpopulation. [PDF]
Curiel-Gomez E +4 more
europepmc +1 more source
Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa +11 more
wiley +1 more source

