Results 191 to 200 of about 72,827 (301)

Epitranscriptomic control of telomere maintenance. [PDF]

Mol Biol Rep
Ahi EP, Ghasemishahrestani Z.
europepmc   +1 more source

Inducible CRISPR/Cas systems in precision oncology: Current applications and future perspectives

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Inducible CRISPR/Cas systems enable spatiotemporal genome editing in precision oncology. Chemical, optical, physical, and microenvironmental stimuli provide distinct control strategies. Conditional activation may reduce off‐target exposure and basal nuclease activity.
Ziliang Ding, Yukun Wei, Yong Han, Pengfei Gu   +3 more
wiley   +1 more source

Improvement of fertility in female mice by treatment with novel telomerase-increasing compounds. [PDF]

Reprod Biol Endocrinol
Abramov M, Har-Vardi I, Assenheim L, Tsory S, Bar Gil E, Priel E.   +5 more
europepmc   +1 more source

Relationship between hTERT levels and oxidative stress in epilepsy patients

Epilepsia Open, Volume 11, Issue 3, Page 752-763, June 2026.
Abstract Objective Human telomerase reverse transcriptase (hTERT) is a key determinant of telomere maintenance and cellular aging. Oxidative stress plays a role in neurodegenerative processes by causing cellular damage through increased reactive oxygen species.
Muhammed Mehdi Üremiş, Deniz Tuncel Berktaş, Nuray Üremiş, Fatma İnanç Tolun   +3 more
wiley   +1 more source

Author Correction: Renal fibroblasts are involved in fibrogenic changes in kidney fibrosis associated with dysfunctional telomeres

Experimental and Molecular Medicine
Sarita Saraswati, Paula Martínez, Rosa Serrano, Diego Mejías, Osvaldo Graña-Castro, Ruth Álvarez Díaz, Maria A. Blasco   +6 more
doaj   +1 more source

Vicatia thibetica de Boiss Crude Polysaccharide Delay the Aging of the Heart and Kidneys

Food Bioengineering, Volume 5, Issue 2, Page 278-289, June 2026.
Vicatia thibetica de Boiss crude polysaccharide (VTCP) attenuates cardiorenal aging by reducing oxidative stress, suppressing inflammation, and alleviating fibrosis. In naturally aged mice, VTCP remodels the gut microbiota, enriching beneficial short‐chain fatty acid‐producing bacteria. We propose that VTCP protects the heart and kidneys via modulation
Daoxu Zhang, Chengyi Wu, Zhiyang Ding, Yunyu Hong, Yehan Lu, Kunpeng Zhou, Ruixuan Deng, Laijia Li, Chao Li, Yongcheng Yang, Conglong Xia, Jian Li, Wenwen Liu, Faliang An, Zelan Hu   +14 more
wiley   +1 more source

Elevated Serum Telomerase Level and Peripheral Blood <i>hTERT</i> Gene Expression in Patients with Stable Coronary Artery Disease. [PDF]

Genes (Basel)
Ozmen C, Inandiklioglu N, Tepe O, Akray A, Gok M, Gunay I, Iltas A, Yildiz PO, Rahimova H, Demirtas M.   +9 more
europepmc   +1 more source

Polygonati Rhizoma Attenuates Oxidative Stress‐Induced Senescence in Periodontal Ligament Stem Cells

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Network pharmacology identified the potential targets and pathways of Polygonati Rhizoma (PR) against aging‐related periodontitis through PPI, GO/KEGG enrichment, and molecular docking. Experimental validation in a D‐galactose‐induced senescence model of periodontal ligament stem cells showed that PR‐medicated serum attenuated cellular senescence and ...
Xinran Feng, Ying An, Fanfan Hou, Qian Guo, Shanshan Cai, Hongbin Xu, Youfu He   +6 more
wiley   +1 more source

Exploring the Mechanisms of Total Saponins of Black Ginseng and Ginsenoside Rg3 Against Doxorubicin‐Induced Cardiotoxicity

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
TSF and Rg3 demonstrate significant cardioprotective effects against DOX‐induced cardiotoxicity (DIC) by mitigating oxidative stress, inflammation, and apoptosis while preserving mitochondrial function. These findings provide novel insights into the clinical relevance of TSF and Rg3 in the management of DIC.
Linlin Liu, Peiyuan Dou, Xiaotong Zhang, Xiaoku Ran, Deqiang Dou, Xiaodong Lv   +5 more
wiley   +1 more source

The Missing Piece: Functional Telomerase Restored in the Beetle Model. [PDF]

Genome Biol Evol
Fajkus P, Štefanovie B, Závodník M, Havlová K, Fojtová M, Peška V, Fajkus J.   +6 more
europepmc   +1 more source