Results 191 to 200 of about 161,718 (344)
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Molecular imaging of telomerase and the enzyme activity-triggered drug release by using a conformation-switchable nanoprobe in cancerous cells [PDF]
Hai Shi +6 more
openalex +1 more source
Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang +13 more
wiley +1 more source
Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications
The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed +3 more
wiley +1 more source
Structural biology of telomeres and telomerase
E. Smith, D. Pendlebury, J. Nandakumar
semanticscholar +1 more source
Author Correction: HuR regulates telomerase activity through TERC methylation [PDF]
Hao Tang +23 more
openalex +1 more source
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
M. Blasco +6 more
semanticscholar +1 more source
Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal +14 more
wiley +1 more source

