Leukocyte telomere length and circulating MiRNAs in relation to cardiovascular outcomes in older adults. [PDF]
La Grotta R +7 more
europepmc +1 more source
RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan +3 more
wiley +1 more source
Distinct roles of chronotype, daytime napping, and sleep duration in biological and functional aging: a univariable and multivariable Mendelian randomization study. [PDF]
Zhang Z +5 more
europepmc +1 more source
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
Editorial: Unraveling the complexities of premature aging: mechanisms and interventions. [PDF]
Choubey M, Srivastava S, Kumar V.
europepmc +1 more source
Genome Assemblies of the MY73 Parental Lines and Genetic Dissection of Its Superior Performance
Plant Biotechnology Journal, EarlyView.
Haixia Zeng +10 more
wiley +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Molecular Mechanisms of Accelerated Ageing in Geriatric Depression: Interplay of Telomere Attrition, Mitochondrial Dysfunction and Cellular Senescence. [PDF]
Revi Shanker P, Dorajoo R.
europepmc +1 more source
Reduced CHMP7 Expression Compromises Telomere Integrity in Mammalian Cells. [PDF]
Burla R +5 more
europepmc +1 more source

