Results 51 to 60 of about 57,502 (259)
Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.
PLoS ONE, 2014 Oxidative stress is involved in the pathogenesis of airway obstruction in α1-antitrypsin deficient patients. This may result in a shortening of telomere length, resulting in cellular senescence.
Aabida Saferali +5 more
doaj +1 more source
Is telomere length associated with mate choice in a songbird with a high rate of extra-pair paternity? [PDF]
PLoS ONE, 2017 Telomere length is related to aging in many eukaryotes and the rate of telomere attrition has been suggested to reflect individual genetic quality. Telomere length could thus have implications for mate choice. We investigated telomere length variation in
Arild Johnsen +3 more
doaj +1 more source
Telomere length in human blastocysts [PDF]
Reproductive BioMedicine Online, 2014 This is a retrospective study aiming to assess telomere length in human embryos 4 days post fertilization and to determine whether it is correlated to chromosomal ploidy, embryo developmental rate and patient age. Embryos were donated from patients undergoing treatment in the assisted conception unit.
Anastasia, Mania +5 more
openaire +2 more sources
Advanced Science, EarlyView.BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou +9 more
wiley +1 more source
Association between telomere shortening and ageing during occupational exposure [PDF]
Journal of Medical Biochemistry, 2012 Telomere length is considered as a biomarker of ageing, resulting in shortening during the process. The present investigation was an attempt to determine the relative telomere length in mechanical workshop workers.
Sima Ataollahi Eshkoor +5 more
doaj
Gravidity is not associated with telomere length in a biracial cohort of middle-aged women: The Coronary Artery Risk Development in Young Adults (CARDIA) study. [PDF]
PLoS ONE, 2017 OBJECTIVE:Having experienced 2-3 births is associated with reduced mortality versus women with
Abbi D Lane-Cordova +5 more
doaj +1 more source
Clinical and Research Journal in Internal Medicine, 2023 Background: Obesity is a prominent avoidable cause of mortality and a growing health concern in both adults and children throughout the world. The study's goal is to measure leucocyte telomere length and its relationship with leptin throughout the BMI ...
Anurag Yadav +4 more
doaj +1 more source
Telomere length and cardiovascular aging
Annals of Medicine, 2012 Telomeres are located at the end of chromosomes. They are composed of repetitive TTAGGG tandem repeats and associated proteins of crucial importance for telomere function. Telomeric DNA is shortened by each cell division until a critical length is achieved and the cell enters senescence and eventually apoptosis.
Frej, Fyhrquist, Outi, Saijonmaa
openaire +2 more sources
Telomere Length: Implications for Atherogenesis
Current Atherosclerosis Reports, 2023 Abstract Purpose of Review The purpose of the study is to explore the evidence linking telomere length with atherosclerotic ischemic disease. Recent Findings There has been a recent expansion in strategies for measuring telomere length, including analyzing genome sequence ...
Hao Yin, J. Geoffrey Pickering
openaire +2 more sources
Advanced Science, EarlyView.HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang +9 more
wiley +1 more source