Results 31 to 40 of about 2,052,365 (293)

The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines [PDF]

, 2014
Copyright @ 2014 the authors. This article is made available through the Brunel Open Access Publishing Fund. It is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution ...
Slijepcevic, P, Terry Roberts, Yasaei, H, Roberts, T, Azadeh Motevalli, Motevalli, A, Predrag Slijepcevic, Sara Anjomani Virmouni, Hemad Yasaei, Virmouni, SA   +9 more
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Telomere length attrition, a marker of biological senescence, is inversely correlated with triglycerides and cholesterol in South Asian males with type 2 diabetes mellitus [PDF]

, 2012
South Asians have a higher risk of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) than white Caucasians, for a given BMI. Premature biological ageing, assessed by reduction in telomere length (TL), may be mediated by factors resulting ...
Miller, M.A., da Silva, NF, Barnett, Anthony H., Al-Attas, O., Miller, MA, da Silva, Nancy F., Kelly, M. Ann, Tripathi, G, Al-Attas, Omar S., Al-Daghri, Nasser M., Cappuccio, Francesco, Kelly, Ann M., Bellary, Srikanth, Kumar, S., da Silva, N.F., McTernan, Philip G., Sabico, S, O'Hare, JP, Tripathi, Gyanendra, Cappuccio, Francesco P., McTernan, P. G., Alokail, M., Al-Daghri, NM, Al-Attas, Omar, Miller, Michelle A., Al-Daghri, N.M., Harte, A.L., Bellary, S., Barnett, Anthony, Bellary, S, Al-Daghri, Nasser M, Kelly, A., Sabico, Shaun, McTernan, PG, Alokail, Majed S., Al-Attas, O, Alokail, M, Tripathi, G., Barnett, A.H., Harte, AL, Harte, Alison L., Kelly, A, O'Hare, Joseph P., Kumar, Sudhesh, O'Hare, J.P., Sabico, S., Cappuccio, FP, Alokail, Majed, McTernan, P.G., Kumar, S, O'Hare, J. Paul, Cappuccio, F.P.   +51 more
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Telomere length comparison between oral cells and blood cells among neonates

The Turkish Journal of Pediatrics, 2019
Telomere length, measured from blood cells, is commonly used as the standard telomere length of the whole body. The relationship between blood telomere length and oral telomere length is still unclear, especially among neonates.
Mandar Bhattacharya, Pranami Bhaumik, Subrata Kumar-Dey   +2 more
doaj   +1 more source

Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition [PDF]

, 2013
© 2013 Yasaei et al.; licensee BioMed Central Ltd.This article has been made available through the Brunel Open Access Publishing Fund.Telomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity.
Slijepcevic, P, Yaghoub Gozaly-Chianea, Yasaei, H, Predrag Slijepcevic, Hemad Yasaei, Gozaly-Chianea, Y   +5 more
core   +1 more source

Telomere length determinants in childhood [PDF]

Clinical Chemistry and Laboratory Medicine (CCLM), 2019
Abstract Telomere length (TL) is a dynamic marker that reflects genetic predispositions together with the environmental conditions of an individual. It is closely related to longevity and a number of pathological conditions. Even though the extent of telomere research in children is limited compared to that of adults, there have been a ...
Gorenjak, Vesna, Petrelis, Alexandros, Stathopoulou, Maria, Visvikis-Siest, Sophie   +3 more
openaire   +2 more sources

Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort [PDF]

, 2011
BACKGROUND: It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease.
Batty, G.D., McGlynn, LM, Jennifer S McLean, Johnson, P.C.D., MacIntyre, Alan, Ford Ian, Yoga Nathan (12346540), Tannahill, Carol, Carol Tannahill, McLean, JS, McGinty, A., Liane M. McGlynn (12597766), Millar, K, MacIntyre, A., McConnachie, A, Burns Harry, MacIntyre Alan, Cavanagh Jonathan, Cavanagh, Jonathan, Tannahill Carol, Shiels, P.G., Chris J. Packard, Jonathan Cavanagh (125077), Deans, K.A., Kevin A. Deans, McGinty Agnes, Chris J. Packard (12592780), Tannahill, C., Keith Millar, Jennifer S. Mclean, Ford, I, Sattar, N., G David Batty, Kevin A. Deans (12592774), McGlynn Liane M., Burns, Harry, Ford, I., Paul G Shiels, Sattar Naveed, Naveed Sattar (8785), Batty, David G., Harry Burns (125075), McConnachie Alex, Liane M. Mcglynn, Packard, C.J., Burns, H, McGinty, Agnes, Miller, Keith, Cavanagh, J., Johnson, Paul C.D., McLean, Jennifer S., Sattar, Naveed, Packard, CJ, Batty G. David, Batty, GD, Johnson, PCD, Shiels, Paul G., Shiels, PG, Paul C. D. Johnson, G. David Batty, Paul C D Johnson, McLean Jennifer S., Sattar, N, Chris J Packard, Burns, H., Millar, K., McGinty, A, Ian Ford, Alex McConnachie (104022), Agnes McGinty, Deans Kevin A., Velupillai, YN, Jennifer S. McLean (12592768), McConnachie, A., Ian Ford (30666), MacIntyre, A, Millar Keith, Velupillai Yoga N., Paul C.D. Johnson (12597769), McConnachie, Alex, Deans, KA, McGlynn, L.M., Naveed Sattar, Paul G. Shiels (12592783), Ford, Ian, Liane M McGlynn, Shiels Paul G., Agnes McGinty (212297), Keith Miller (2363098), Kevin A Deans, Paul G. Shiels, Jonathan Cavanagh, Carol Tannahill (212305), Chris J, McGlynn, Liane M., Deans, Kevin A., Alex McConnachie, David G. Batty (12592771), Cavanagh, J, Velupillai, Y.N., Alan MacIntyre, Johnson Paul C. D., Nathan, Yoga, Alan MacIntyre (212284), McLean, J.S., Tannahill, C, Yoga N Velupillai, Harry Burns, Packard Chris J., Packard, Chris J., Yoga N. Velupillai   +110 more
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Expression of shelterin and shelterin-associated genes in breast cancer cell lines [PDF]

, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Mammalian telomeric DNA consists of tandem repeats of the sequence TTAGGG associated with a specialized set of proteins, known collectively as Shelterin ...
Motevalli, Azadeh
core   +7 more sources

Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort. [PDF]

, 2014
Cross-sectional studies reported associations between short leucocyte telomere length (LTL) and measures of vascular and cardiac damage. However, the contribution of LTL dynamics to the age-related process of cardiovascular (CV) remodelling remains ...
Kahn, T, Kahn, Tauseef, Hardy, R, Von Zglinicki, Thomas, D'Aiuto, F, MASI, STEFANO, Martin-Ruiz, C, Ghosh, AK, Hughes, A, Deanfield, John Eric, Wong, A, Kuh, Diana, Masi, S, NSHD scientific and data collection teams, ., Whincup, Peter, von Zglinicki, T, Hardy, Rebecca, Whincup, P, Deanfield, JE, Kuh, D, NSHD scientific and data collection teams, Wong, Andrew, D'Aiuto, Francesco, Ghosh, Arjun K., Hughes, Alan, Martin Ruiz, Carmen   +25 more
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Defective Artemis causes mild telomere dysfunction [PDF]

, 2010
This article has been made available through the Brunel Open Access Publishing Fund.Background: Repair of DNA double strand breaks by non-homologous end joining (NHEJ) requires several proteins including Ku, DNA-PKcs, Artemis, XRCC4, Ligase IV and XLF ...
Slijepcevic, P, Yasaei, H, Predrag Slijepcevic, Hemad Yasaei   +3 more
core   +1 more source

Telomere length and incident atrial fibrillation - data of the PREVEND cohort.

PLoS ONE, 2017
BackgroundThe incidence of atrial fibrillation (AF) increases with age. Telomere length is considered a marker of biological ageing. We investigated the association between leukocyte telomere length and incident AF in the Dutch Prevention of Renal and ...
Joylene E Siland, Bastiaan Geelhoed, Isabelle C van Gelder, Pim van der Harst, Michiel Rienstra   +4 more
doaj   +1 more source