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Nature Communications, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Robert Lu +9 more
doaj +1 more source
The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
Nature Communications, 2019 ALT telomeres experience DNA damage that may drive recombination-based telomere elongation. Here, the authors reveal that FANCM plays a critical role in the suppression of ALT activity through its interaction with the BTR (BLM-TOP3A-RMI) complex.
Robert Lu +9 more
doaj +1 more source
Telomere length in human blastocysts [PDF]
Reproductive BioMedicine Online, 2014 This is a retrospective study aiming to assess telomere length in human embryos 4 days post fertilization and to determine whether it is correlated to chromosomal ploidy, embryo developmental rate and patient age. Embryos were donated from patients undergoing treatment in the assisted conception unit.
Anastasia, Mania +5 more
openaire +2 more sources
Telomere length comparison between oral cells and blood cells among neonates
The Turkish Journal of Pediatrics, 2019 Telomere length, measured from blood cells, is commonly used as the standard telomere length of the whole body. The relationship between blood telomere length and oral telomere length is still unclear, especially among neonates.
Mandar Bhattacharya +2 more
doaj +1 more source
Factors related to telomere length [PDF]
Brain, Behavior, and Immunity, 2016 We appreciate the comments by Tasdemir and Oz on our recent paper in Brain, Behavior & Immunity (Prather et al., 2015). The question of what is “causing bad sleep” is certainly an important one, and the authors list some of the key culprits (e.g., excess alcohol consumption, caffeine at night, and menopausal symptoms).
Aric A, Prather +2 more
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Telomere length and incident atrial fibrillation - data of the PREVEND cohort.
PLoS ONE, 2017 BackgroundThe incidence of atrial fibrillation (AF) increases with age. Telomere length is considered a marker of biological ageing. We investigated the association between leukocyte telomere length and incident AF in the Dutch Prevention of Renal and ...
Joylene E Siland +4 more
doaj +1 more source
Telomere tracking from birth to adulthood and residential traffic exposure
BMC Medicine, 2017 Background Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length.
Esmée M. Bijnens +9 more
doaj +1 more source
Telomere length determinants in childhood [PDF]
Clinical Chemistry and Laboratory Medicine (CCLM), 2019 Abstract Telomere length (TL) is a dynamic marker that reflects genetic predispositions together with the environmental conditions of an individual. It is closely related to longevity and a number of pathological conditions. Even though the extent of telomere research in children is limited compared to that of adults, there have been a ...
Gorenjak, Vesna +3 more
openaire +2 more sources
Telomere shortening unrelated to smoking, body weight, physical activity, and alcohol intake: 4,576 general population individuals with repeat measurements 10 years apart. [PDF]
PLoS Genetics, 2014 Cross-sectional studies have associated short telomere length with smoking, body weight, physical activity, and possibly alcohol intake; however, whether these associations are due to confounding is unknown.
Maren Weischer +2 more
doaj +1 more source
iScienceSummary: Alternative lengthening of telomeres (ALT) is a homology-directed repair mechanism that becomes activated in a subset of cancers to maintain telomere length.
Robert Lu +5 more
doaj +1 more source