Results 21 to 30 of about 59,573 (233)

Author Correction: The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

open access: yesNature Communications, 2019
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Robert Lu   +9 more
doaj   +1 more source

The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

open access: yesNature Communications, 2019
ALT telomeres experience DNA damage that may drive recombination-based telomere elongation. Here, the authors reveal that FANCM plays a critical role in the suppression of ALT activity through its interaction with the BTR (BLM-TOP3A-RMI) complex.
Robert Lu   +9 more
doaj   +1 more source

Telomere length in human blastocysts [PDF]

open access: yesReproductive BioMedicine Online, 2014
This is a retrospective study aiming to assess telomere length in human embryos 4 days post fertilization and to determine whether it is correlated to chromosomal ploidy, embryo developmental rate and patient age. Embryos were donated from patients undergoing treatment in the assisted conception unit.
Anastasia, Mania   +5 more
openaire   +2 more sources

Telomere length comparison between oral cells and blood cells among neonates

open access: yesThe Turkish Journal of Pediatrics, 2019
Telomere length, measured from blood cells, is commonly used as the standard telomere length of the whole body. The relationship between blood telomere length and oral telomere length is still unclear, especially among neonates.
Mandar Bhattacharya   +2 more
doaj   +1 more source

Factors related to telomere length [PDF]

open access: yesBrain, Behavior, and Immunity, 2016
We appreciate the comments by Tasdemir and Oz on our recent paper in Brain, Behavior & Immunity (Prather et al., 2015). The question of what is “causing bad sleep” is certainly an important one, and the authors list some of the key culprits (e.g., excess alcohol consumption, caffeine at night, and menopausal symptoms).
Aric A, Prather   +2 more
openaire   +2 more sources

TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT

open access: yesEMBO Molecular Medicine, 2022
In some types of cancer, telomere length is maintained by the alternative lengthening of telomeres (ALT) mechanism. In many ALT cancers, the α‐thalassemia/mental retardation syndrome X‐linked (ATRX) gene is mutated leading to the conclusion that the ATRX
Alexandre de Nonneville   +15 more
doaj   +1 more source

Telomere length and incident atrial fibrillation - data of the PREVEND cohort.

open access: yesPLoS ONE, 2017
BackgroundThe incidence of atrial fibrillation (AF) increases with age. Telomere length is considered a marker of biological ageing. We investigated the association between leukocyte telomere length and incident AF in the Dutch Prevention of Renal and ...
Joylene E Siland   +4 more
doaj   +1 more source

Telomere tracking from birth to adulthood and residential traffic exposure

open access: yesBMC Medicine, 2017
Background Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length.
Esmée M. Bijnens   +9 more
doaj   +1 more source

An Analysis of Telomere Length in Sarcoidosis [PDF]

open access: yesThe Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2007
We investigated telomere (terminal restriction fragment [TRF]) length in 111 patients with sarcoidosis regarding both the mean TRF length and the telomere length distribution. A significant decrease was observed in the mean TRF length in sarcoidosis patients in comparison to the age-matched controls, whereas a decreased telomere length was only ...
Jing Zhi, Guan   +6 more
openaire   +2 more sources

Telomere length in myelodysplastic syndromes [PDF]

open access: yesAmerican Journal of Hematology, 1997
We have studied telomere length in the bone marrow cells or the granulocyte and lymphocyte cell fractions of 54 patients with myelodysplastic syndromes (MDS) by Southern blot hybridization using the (TTAGGG)4 probe. The average telomere length expressed as the peak telomere repeat array (TRA) in the peripheral blood, or bone marrow samples obtained ...
Boultwood, J   +8 more
openaire   +4 more sources

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