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Nature Communications, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Robert Lu +9 more
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Telomere length comparison between oral cells and blood cells among neonates
The Turkish Journal of Pediatrics, 2019 Telomere length, measured from blood cells, is commonly used as the standard telomere length of the whole body. The relationship between blood telomere length and oral telomere length is still unclear, especially among neonates.
Mandar Bhattacharya +2 more
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Telomere length determinants in childhood [PDF]
Clinical Chemistry and Laboratory Medicine (CCLM), 2019 Abstract Telomere length (TL) is a dynamic marker that reflects genetic predispositions together with the environmental conditions of an individual. It is closely related to longevity and a number of pathological conditions. Even though the extent of telomere research in children is limited compared to that of adults, there have been a ...
Gorenjak, Vesna +3 more
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Telomere length and incident atrial fibrillation - data of the PREVEND cohort.
PLoS ONE, 2017 BackgroundThe incidence of atrial fibrillation (AF) increases with age. Telomere length is considered a marker of biological ageing. We investigated the association between leukocyte telomere length and incident AF in the Dutch Prevention of Renal and ...
Joylene E Siland +4 more
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Telomere tracking from birth to adulthood and residential traffic exposure
BMC Medicine, 2017 Background Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length.
Esmée M. Bijnens +9 more
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Telomere length in myelodysplastic syndromes [PDF]
American Journal of Hematology, 1997 We have studied telomere length in the bone marrow cells or the granulocyte and lymphocyte cell fractions of 54 patients with myelodysplastic syndromes (MDS) by Southern blot hybridization using the (TTAGGG)4 probe. The average telomere length expressed as the peak telomere repeat array (TRA) in the peripheral blood, or bone marrow samples obtained ...
Boultwood, J +8 more
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iScienceSummary: Alternative lengthening of telomeres (ALT) is a homology-directed repair mechanism that becomes activated in a subset of cancers to maintain telomere length.
Robert Lu +5 more
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Telomere shortening unrelated to smoking, body weight, physical activity, and alcohol intake: 4,576 general population individuals with repeat measurements 10 years apart. [PDF]
PLoS Genetics, 2014 Cross-sectional studies have associated short telomere length with smoking, body weight, physical activity, and possibly alcohol intake; however, whether these associations are due to confounding is unknown.
Maren Weischer +2 more
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Postępy Higieny i Medycyny Doświadczalnej, 2013 Telomeres protect the ends of chromosomes maintaining genome stability. The activity of telomerase enzyme, or alternatively the process of recombination, regulates the length of telomeres. In the absence of these mechanisms, excessive shortening of telomeres reach its critical level.
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PLoS Genetics, 2006 Telomere length-variation in deletion strains of Saccharomyces cerevisiae was used to identify genes and pathways that regulate telomere length. We found 72 genes that when deleted confer short telomeres, and 80 genes that confer long telomeres relative ...
Tonibelle Gatbonton +7 more
doaj +2 more sources