Results 1 to 10 of about 627 (158)

Complete Denture as Pivot Splint: A Better Approach for the Treatment of Temporomandibular Joint Osteoarthritis [PDF]

Clinical Case Reports
Temporomandibular joint osteoarthritis (TMJOA) is a degenerative disorder characterized by progressive cartilage degradation, abnormal subchondral bone remodeling, and synovitis. This study presents the management of TMJOA in edentulous patients using an
Jihane El Aoud, Asmae Yadfout, Nadia Merzouk, Jihane Hasnaoui Slaoui   +3 more
doaj   +4 more sources

Interdisciplinary Approach to the Temporomandibular Joint Osteoarthritis—Review of the Literature [PDF]

Medicina, 2020
Background and objectives: There is an increasing number of patients applying for dental treatment who suffer from temporomandibular joint osteoarthritis (TMJOA).
Marcin Derwich, Maria Mitus-Kenig, Elzbieta Pawlowska   +2 more
doaj   +7 more sources

Comparative review: clinical and pathological heterogeneity in knee versus temporomandibular joint osteoarthritis [PDF]

Frontiers in Bioengineering and Biotechnology
Temporomandibular joint osteoarthritis (TMJOA) remains a clinically underrecognized and insufficiently studied disorder, despite exerting a comparable impact on quality of life as knee osteoarthritis (knee OA).
Jiannan Zhao, Ruoyi Wang, Songsong Zhu, Zhen Li, Rong Ren, Nan Jiang   +5 more
doaj   +5 more sources

Nano MiRNA‐Functionating Tetrahedral Framework Nucleic Acid for Cartilage‐Targeted Ferritinophagy Modulation to Attenuate Temporomandibular Joint Osteoarthritis [PDF]

Small Science
Current clinical interventions lack effective strategies to arrest temporomandibular joint osteoarthritis (TMJOA) progression. Emerging evidence highlights the therapeutic potential of microRNAs (miRNAs) in osteoarthritis (OA) management, though critical
Wenxiu Yuan, Maotuan Huang, Linxin Chen, Sihang Chen, Hanyu Lin, Nengwen Huang, Yifeng Xing, Chengchaozi Wang, Jie Lu, Min Fu, Linyu Xu, Jiang Chen   +11 more
doaj   +3 more sources

METTL3-mediated fibroblast-like synoviocytes senescence promotes temporomandibular joint osteoarthritis progression [PDF]

Communications Biology
Temporomandibular joint osteoarthritis (TMJOA) is a disease that affects the TMJ and is associated with degenerative changes in the articular cartilage. Fibroblast-like synoviocytes (FLSs) have been found to contribute to osteoarthritis.
Kun Tian, Qin Du, Jun Guo, Wen Liao, Xianrui Yang, Shuang Lai, Juan Liao, Yandong Mu, Li Xiao   +8 more
doaj   +2 more sources

Drug delivery systems for treatment of temporomandibular joint osteoarthritis

Frontiers in Pharmacology, 2022
The number of people suffering from temporomandibular joint osteoarthritis (TMJOA) has been increasing. TMJOA cause joint noise, pain on TMJ and/or masticatory muscles, and restricted mandibular movement, which disturb eating, laughing and conversation ...
Xinqi Huang, Xuefeng Pan, Xiner Xiong, Zhihe Zhao, Xiao Cen   +4 more
doaj   +3 more sources

Nell-1 regulates fibrocartilage stem cells and alleviates temporomandibular joint osteoarthritis progression by inhibiting hedgehog pathway [PDF]

Journal of Orthopaedic Surgery and Research
Background Nel-like molecule-1 (Nell-1) could prevent the damage of cartilage in osteoarthritis (OA), including temporomandibular joint osteoarthritis (TMJOA), though, the definite mechanism of the process is unclear.
Shiyu Hu, Na Wu, Cunyi Wang, Wen Li, Jiejun Shi   +4 more
doaj   +2 more sources

Photothermal reprogramming of synovial M1 macrophages reshapes the pro-inflammatory microenvironment to reverse temporomandibular joint osteoarthritis [PDF]

Journal of Nanobiotechnology
Temporomandibular joint osteoarthritis (TMJOA) involves progressive synovial inflammation-driven cartilage degeneration. While thermotherapy empirically alleviates symptoms, its immunomodulatory mechanism remains elucidated.
Yanyi Wang, Jiangyan Ren, Tingyu Ren, Baochao Li, Jianchuan Ran, Huijuan Wang, Ziwei Huang, Diya Xie, Tao Liu, Linzhong Yang, Jinglun Zhang, Caixia Zhang, Zhi Wang, Xingyu Luo, Lei Zheng, Xiaoji Xie, Huang Li, Wei Han   +17 more
doaj   +2 more sources

OX40L in endothelial cells promotes temporomandibular joint subchondral bone angiogenesis and osteoclastogenesis in mice [PDF]

Bone & Joint Research
Aims: Subchondral vascular proliferation is a substantial pathological manifestation of temporomandibular joint osteoarthritis (TMJOA), yet its underlying mechanisms remain unclear.
Yifan Zheng, Chufeng Liu, Zhihao Liao, Jiayu Lin, Yuxiao Luo, Xia Yang, Xuepei Cai, Zedong Lan   +7 more
doaj   +2 more sources

SGK1 triggers cartilage degradation in TMJOA via FoxO1/autophagy [PDF]

Arthritis Research & Therapy
Background Temporomandibular joint osteoarthritis (TMJOA) is a prevalent inflammatory disease with unclear pathogenesis. Serum and glucocorticoid-inducible kinase 1 (SGK1) has been implicated in osteoarthritis-related cartilage degeneration.
Hongyao Tang, Chuan Ma, Mengchen Xu, Gaoyi Wu, Na Li, Lei Chen   +5 more
doaj   +2 more sources