Insights into the Notch signaling pathway in degenerative musculoskeletal disorders: Mechanisms and perspectives [PDF]
Degenerative musculoskeletal disorders are a group of age-related diseases of the locomotive system that severely affects the patient's ability to work and cause adverse sequalae such as fractures and even death.
Chen, Lin +8 more
core +4 more sources
Quantitative bone imaging biomarkers and joint space analysis of the articular Fossa in temporomandibular joint osteoarthritis using artificial intelligence models [PDF]
Temporomandibular joint osteoarthritis (TMJ OA) is a disease with a multifactorial etiology, involving many pathophysiological processes, and requiring comprehensive assessments to characterize progressive cartilage degradation, subchondral bone ...
Al Turkestani, Najla +8 more
core +2 more sources
Ion channels involved in inflammation and pain in osteoarthritis and related musculoskeletal disorders [PDF]
Osteoarthritis (OA) is a currently incurable, chronic, progressive, and debilitating musculoskeletal (MSK) condition. One of its hallmark symptoms is chronic nociceptive and neuropathic pain, which significantly reduces the quality of life of patients ...
Choi, Heonsik +5 more
core +1 more source
Minimally Invasive Approach for Diagnosing TMJ Osteoarthritis [PDF]
This study’s objectives were to test correlations among groups of biomarkers that are associated with condylar morphology and to apply artificial intelligence to test shape analysis features in a neural network (NN) to stage condylar morphology in ...
Allohaibi, Z. +21 more
core +2 more sources
HMGB1 is a highly conserved nuclear protein that is rapidly released into the extracellular environment during infection or tissue damage. In osteoarthritis, HMGB1 acts as a pro-inflammatory cytokine inducing a positive feedback loop for synovial ...
Yan Yan Li +4 more
doaj +1 more source
Artificial intelligence and 3D printing technology in orthodontics: future and scope [PDF]
New digital technologies, like in other fields, have revolutionized the health care field and orthodontic practice in the 21st century. They can assist the health care professionals in working more efficiently by saving time and improving patient care ...
Laxmikanth SM +3 more
core +1 more source
Association of Condylar Bone Quality with TMJ Osteoarthritis [PDF]
The etiology and treatment of temporomandibular joint (TMJ) osteoarthritis (TMJOA) remain complex and unclear. Based on clinical observations, we hypothesized that low condylar bone quality is significantly correlated with TMJOA and explored this ...
core +1 more source
Progress of research on the role of primary cilia in cartilage degeneration in temporomandibular joint osteoarthritis [PDF]
Temporomandibular joint osteoarthritis (TMJOA) is characterized by progressive cartilage degeneration, subchondral bone remodeling, chronic inflammation in the synovial tissue and osteophyte formation.
LI Gongchen, HU Ziyue, SUN Yao
doaj +1 more source
Temporomandibular joint osteoarthritis (TMJOA) is a debilitating degenerative disease with high incidence, deteriorating quality of patient life. Currently, due to ambiguous etiology, the traditional clinical strategies of TMJOA emphasize on symptomatic ...
Wenxiu Yuan +12 more
doaj +1 more source
Clinical Perspectives of Non-Coding RNA in Oral Inflammatory Diseases and Neuropathic Pain: A Narrative Review [PDF]
Non-coding RNAs (ncRNAs) represent a research hotspot by playing a key role in epigenetic and transcriptional regulation of diverse biological functions and due to their involvement in different diseases, including oral inflammatory diseases.
Petrović, Nina, Roganović, Jelena
core +1 more source

