Results 101 to 110 of about 294,146 (290)

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

The Early Methionine Supplementation of Ewe Lambs (F0) Modifies Meat Quality Traits of the Progeny (F1, Male Fattening Lambs)

Animals
Adequate management of replacement ewe lambs (F0) in dairy sheep farms during postnatal life may modify the germline cells, thus promoting transmission of intergenerational effects to the offspring (F1). To test this hypothesis, 18 newborn male lambs (F1)
Mahsa Dehnavi, Javier Mateo, Alba Martín, F. Javier Giráldez, Irma Caro, Lara Morán, Sonia Andrés   +6 more
doaj   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

Arthritis &Rheumatology, EarlyView.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, for the TULIP‐SC investigators   +12 more
wiley   +1 more source

Influence of diverse finishing systems on carcass characteristics, proximate composition, and meat quality attributes of striploins from bison heifers

Frontiers in Ecology and Evolution
Bison producers commonly utilize grain- or grass-finishing across both extensive and intensive management systems that can vary in diet composition and nutrient concentration.
Lydia M. O’Sullivan, Reid F. Anema, Garrett T. Weldy, Benjamin J. Carpenter, M. Sebastian Hernandez, Keith R. Underwood, Judson K. Grubbs, Christina E. Bakker, Jerrad F. Legako, Jessica Lovitt, Carter Kruse, Amanda D. Blair   +11 more
doaj   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

Arthritis &Rheumatology, EarlyView.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun, Lingfang Xu, Haibing Chen, Mingshu Sun, Zhiqiang Li, Rui Li, Lidan Ma, Hui Zhang, Aichang Ji, Yuwei He, Na Wu, Le Yan, Robert Terkeltaub, Changgui Li   +13 more
wiley   +1 more source

CO2 stunning improved the meat quality by regulating postmortem muscle cell death

Food Materials Research
The incidence of abnormal meat poses a significant challenge in the meat industry, where stunning serves as a crucial intervention to alleviate pre-slaughter stress and improve meat quality.
Xiao Qiu, Xinrui Mao, Kai Shan, Chunbao Li   +3 more
doaj   +1 more source

Dupilumab‐Related Adverse Events and Intolerance in Aspirin‐Exacerbated Respiratory Disease Patients

International Forum of Allergy &Rhinology, EarlyView.
Lancelot P. Herpin, Randy Bach, Ricardo Bruneto, Kerol A. Faltas, Michael A. Kohanski, James N. Palmer, Nithin D. Adappa, Jennifer E. Douglas, John V. Bosso   +8 more
wiley   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Study of Sensory evaluation and some Physical qualities of Broiler meat fed with Raisins pomace powder

Kufa Journal for Agricultural Sciences
The study aimed to find out the effect of raisins pomace powder additives on the drip and cooking loss, sensory qualities. Broilers were fed on diets containing 0, 10, 20, and 30 grams of raisins pomace powder per kilogram of diet for 5 weeks.
Zaid I.H. Zainy, Ali J. Hammod, Salah Mahdi Al-Jannah   +2 more
doaj   +1 more source

‘The best year’/‘I struggled with everything’: Widening participation experiences of pandemic online learning

British Educational Research Journal, EarlyView.
Abstract Improving retention and graduate outcomes for students from a widening participation (WP) background is key to achieving more equitable outcomes. However, evidence suggests WP students experienced different challenges than their peers during the COVID‐19 pandemic.
Wilhelmiina Toivo, Emily Nordmann, Jacqui Hutchison, Alison Browitt, Jill R. D. MacKay   +4 more
wiley   +1 more source