Results 181 to 190 of about 148,309 (199)
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Reverse transcription of retroviral genomes: mutations in the terminal repeat sequences
Journal of Virology, 1985The process of reverse transcription of retroviral genomes begins with the synthesis of a short DNA molecule near the 5' end of the RNA template. This molecule, termed minus-strand strong-stop DNA, is then translocated to the 3' end of the viral RNA by means of a repeated sequence, the R region, present at both ends of the template.
S P Goff, L I Lobel
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Inverted terminal repeat sequence in the macronuclear DNA of Stylonychia pustulata
Gene, 1980The structure of macronuclear DNA of a hypotrichous ciliate, Stylonychia pustulata, was examined by both electron microscopy and nucleotide sequence analysis. The DNA in the macronucleus consists of small linear molecules with average length of about 3400 base pairs (bp).
Nakai Sumiko +4 more
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The Long Terminal Repeat Sequences of a Novel Human Endogenous Retrovirus
Science, 1984The complete nucleotide sequence of both the 5′ and 3′ long terminal repeats (LTR's) has been determined for a human endogenous retroviral genome. These sequences are 593 and 590 nucleotides long and have diverged from one another by 8.8 percent. The LTR's resemble those of functional mammalian type C retroviruses in length and in the presence and ...
Maurice Cohen, Catherine D. O'Connell
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Two domains in the terminal inverted-repeat sequence of transposon Tn3
Gene, 1990Tn3 and related transposons have terminal inverted repeats (IR) of about 38 bp that are needed as sites for transposition. We made mini-Tn3 derivatives which had a wild-type IR of Tn3 at one end and either the divergent IR of the Tn3-related transposon, gamma delta or IS101, or a mutant IR of Tn3 at the other end.
Eiichi Ohtsubo +3 more
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Retroviral characteristics of the long terminal repeat of murine E.Tn sequences.
The EMBO Journal, 1985E.Tn sequences form a family of long moderately repeated sequences which are abundantly transcribed in the pluripotent cell lineage between day 3.5 and 7.5 of early mouse embryogenesis. The structure of the long terminal repeat (LTR) bordering the E.Tn sequences has been investigated by nucleotide sequencing, primer extension and S1 mapping experiments.
L. Maillet +2 more
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A nearby inverted repeat of the terminal sequence of herpes simplex virus DNA
Biochemical and Biophysical Research Communications, 1976Abstract When herpes simplex virus DNA is digested with λ-exonuclease, annealed, and then mounted for observation in the electron microscope, two types of molecules are seen. One type is circular DNA which forms because the enzyme has revealed the terminal repetition.
Richard W. Hyman +2 more
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Nature, 1984
Although the murine retrovirus SL3-3 is highly leukaemogenic, in both the structure of its genome and in its properties of replication in tissue culture it closely resembles the nonleukaemogenic retrovirus Akv (refs 3, 4). An earlier investigation of the properties of recombinant SL3-3-Akv viruses localized the major determinant of leukaemogenicity ...
William A. Haseltine +5 more
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Although the murine retrovirus SL3-3 is highly leukaemogenic, in both the structure of its genome and in its properties of replication in tissue culture it closely resembles the nonleukaemogenic retrovirus Akv (refs 3, 4). An earlier investigation of the properties of recombinant SL3-3-Akv viruses localized the major determinant of leukaemogenicity ...
William A. Haseltine +5 more
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Gene, 1983
A mouse 1.3-kb EcoRI dispersed repeat sequence that shows homology by hybridisation to the long terminal repeat of intracisternal A-particle genes has been partially sequenced. One of the established sequence regions shows three major features reminiscent of the long terminal repeats of retroviruses. Firstly, a TATA box precedes a putative capping site
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A mouse 1.3-kb EcoRI dispersed repeat sequence that shows homology by hybridisation to the long terminal repeat of intracisternal A-particle genes has been partially sequenced. One of the established sequence regions shows three major features reminiscent of the long terminal repeats of retroviruses. Firstly, a TATA box precedes a putative capping site
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A repetitive DNA sequence in the salmonid fishes similar to a retroviral long terminal repeat
Journal of Molecular Evolution, 1988We describe the characteristics of a repetitive DNA sequence from the rainbow trout and related salmonid fishes that is similar to a retroviral long terminal repeat (LTR). The repeat is 160 bp long and contains a region of homology to the LTR of the avian sarcoma virus.
Gordon H. Dixon, Robert D. Moir
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Cell, 1980
We have determined the nucleotide sequence of the terminal regions of two members of the copia sequence family of D. melanogaster. The first 276 bp at one end of a copia element are repeated in direct orientation at its other end. The direct repeats on a single copia element are identical to each other, but they differ by two nucleotide substitutions ...
Robert W. Levis +2 more
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We have determined the nucleotide sequence of the terminal regions of two members of the copia sequence family of D. melanogaster. The first 276 bp at one end of a copia element are repeated in direct orientation at its other end. The direct repeats on a single copia element are identical to each other, but they differ by two nucleotide substitutions ...
Robert W. Levis +2 more
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