Results 81 to 90 of about 148,309 (199)

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source

Asymmetric Nanofiber Membranes for Simultaneous Moisture Adsorption and Rapid Catalytic Hydrolysis of Nerve Agent Simulants in Atmospheric Environments

Advanced Functional Materials, EarlyView.
Asymmetric nanofiber membranes are constructed for simultaneous moisture adsorption and catalytic hydrolysis of dimethyl 4‐nitrophenyl phosphate (DMNP) in a wide range of relative humidity. The membrane exhibits high moisture adsorption capacity and fast hygroscopic rate.
Xuejiao Wang, Yu‐Xuan Zheng, Chen Ding, Ming Zhang, Zhong‐Zhen Yu, Shaobin Wang, Dongzhi Yang   +6 more
wiley   +1 more source

Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth

Advanced Functional Materials, EarlyView.
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung, Chu‐Chun Liang, Min‐Wei Huang, Tianle Chen, Joshua M. Little, Snehi Shrestha, Yi‐Chen Ethan Li, I‐Chi Lee, Po‐Yen Chen   +8 more
wiley   +1 more source

Edge‐Delocalized Electron Effect on Self‐Expediating Desolvation Kinetics for Low‐Temperature Li─S Batteries

Advanced Functional Materials, EarlyView.
The self‐transformed Schottky heterojunction on MXene is developed to facilitate the dissociation of Li (solvent)x+ to achieve fast Li+ desolvation to promote rapid sulfur conversion kinetics by decreasing the related barriers, contributing to high‐performance Li─S batteries under low‐temperatures.
Yongzheng Zhang, Xiang Li, Yanli Wang, Jianghao Zhu, Yinze Zuo, Xiaomin Cheng, Tao Rong, Jing Zhang, Yang Hu, Hongzhen Lin, Jian Wang, Liang Zhan, Licheng Ling   +12 more
wiley   +1 more source

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim, Ning Guo, Zong Yao Tan, Xing Gao, Pouria Fattahi, Haijiao Liu, Jeehan Chang, Mousa Younesi, Selice Jung, Yewhan Chung, Minkyung Song, Michelle Jung, Dan Dongeun Huh   +12 more
wiley   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

Advanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim, Jin Woong Lee, Piper A. Rawding, Mari Iida, Carter Kim, Kourtney L. Kostecki, Michael J. Poellmann, Bridget Crossman, Ashley S. Liu, YoungSoo Kim, Deric L. Wheeler, Seungpyo Hong   +11 more
wiley   +1 more source

Fabrication of a Lipopolysaccharide‐Targeting Peptide‐Based Colloid for Alleviating Carbapenem‐Resistant Enterobacteriaceae‐Induced Cutaneous Infection

Advanced Healthcare Materials, EarlyView.
In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng, Xinyi Ding, Chenyu Liu, Sheng Chen, Kin‐Fai Chan, Sharon Shui Yee Leung   +5 more
wiley   +1 more source

One‐Shot Remote Integration of Macromolecular Synaptic Elements on a Chip for Ultrathin Flexible Neural Network System

Advanced Materials, EarlyView.
A novel one‐shot integration electropolymerization (OSIEP) method is developed as a breakthrough on the intricate photolithographic steps, enabling to compress all processes from synthesis to channel integration in one‐shot manufacturing. The specially designed dual bipolar electrodes provide the targeted depositions of poly(3,4‐ethylenedioxythiophene)
Jiyun Lee, Jaehoon Lee, Hyeonsu Bang, Tae Woong Yoon, Jong Hwan Ko, Guobing Zhang, Ji‐Sang Park, Il Jeon, Sungjoo Lee, Boseok Kang   +9 more
wiley   +1 more source

Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions

Advanced Materials, EarlyView.
Implantable devices significantly enhance healthcare but are limited by battery life. Ultrasound power transfer technology offers a promising solution for sustainable operation. This review addresses gaps in current research, particularly in sound field analysis and energy efficiency optimization.
Yi Zheng, Zhuomin Zhang, Yanhu Zhang, Qiqi Pan, Xiaodong Yan, Xuemu Li, Zhengbao Yang   +6 more
wiley   +1 more source