Results 161 to 170 of about 203,484 (292)

Combining advanced 3D spheroid-based skin models with deep-learning-based image analysis enables in-depth investigation of keratinocyte differentiation and barrier function. [PDF]

Front Bioeng Biotechnol
Cesetti T, Buerger C, Couturier N, Nuernberg E, Bruch R, Vitacolonna M, Lang V, Hafner M, Reischl M, Fauth T, Rudolf R.   +10 more
europepmc   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Aging-Related Myocardial Susceptibility Lowers Cardiac Tolerance to Chronic Intermittent Hypoxia Through Dynamin-Related Protein 1-Associated Mitochondrial Vulnerability. [PDF]

Aging Cell
Su Y, Miao Y, Tan J, Wang F, Zhang Q.
europepmc   +1 more source

TERT-BUTYL TERT-BUTYLDIMETHYLSILYLGLYOXYLATE: A USEFUL CONJUNCTIVE REAGENT [PDF]

Organic Syntheses, 2008
openaire   +1 more source

Atomically Dispersed Fe‐Modified SnS for Sn‐Centered Peroxymonosulfate Activation Toward Acetaminophen Degradation

Advanced Science, EarlyView.
Atomically dispersed Fe regulates the local electronic environment and surface properties of SnS, while PMS preferentially coordinates to Sn through Sn–O interaction. Fe incorporation further enhances the Sn–OPMS interfacial interaction, facilitating Sn‐centered PMS activation and the generation of SO4•−/•OH for APAP degradation, thereby clarifying the
Shuhui Liu, Yantao Wang, Ya Liu, Jingkai Lin, Shaobin Wang, Wenjie Tian   +5 more
wiley   +1 more source

THOR methylation as a pan-cancer mechanism of <i>TERT</i> activation: toward a clinically relevant epigenetic biomarker. [PDF]

Front Oncol
Chebly A, Chevret E.
europepmc   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Rapid progression of recurrent intracranial solitary fibrous tumor following a previously reported TERT-wild-type primary tumor: a case report. [PDF]

Front Oncol
Shao L, Yang C, Teng X, Yang J, Li J, Gu Y, Sun S.   +6 more
europepmc   +1 more source

Near‐Unity Photothermal Conversion in Bimetallic M44 and M81 Nanoclusters Enables NIR‐Driven Photo‐Thermo‐Electricity Generation

Advanced Science, EarlyView.
Atomically precise nanoclusters of Au/Ag alloys are explored as high‐performance photothermal materials, delivering record‐high photothermal efficiencies (up to 91%). Photo‐thermo‐electricity is further demonstrated by integrating nanocluster films with thermoelectric devices.
Avirup Sardar, Abhrojyoti Mazumder, Weijie Ji, Guiying He, Yitong Wang, Lianshun Luo, Sihan Chen, Rongchao Jin   +7 more
wiley   +1 more source

Conditional Senescence and Longevity Mechanisms in Early-Branching Metazoans: Insights from <i>Hydra</i>. [PDF]

Curr Issues Mol Biol
Russo V, Udroiu I, Cianfanelli V, D'Ezio V, Proietti R, Sgura A, Persichini T, Colasanti M.   +7 more
europepmc   +1 more source