Results 161 to 170 of about 367,883 (311)

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

Frequency of TERT Promoter Mutations in Ameloblastoma: A Retrospective Study. [PDF]

Diagnostics (Basel)
Kim MS, Son SA, Choi SY.
europepmc   +1 more source

Tuned Oxidation Potential of Continuous Defective Photocatalyst for Selective Biomass Conversion

Advanced Science, EarlyView.
This work develops a wavelength‐controlled photocatalytic strategy that utilizes defect‐state excitation to modulate oxidative capability for biomass selective conversion. By tuning the photooxidation potential to match substrate reactivity, the system suppresses overoxidation and enables the selective formation of value‐added products, providing a ...
Longfei Hong, Huiyan Zhang, Liangdong Hu, Xiang Gao, Lianhua Xu, Qingyu Liu, Rui Xiao, Sheng Chu   +7 more
wiley   +1 more source

Telomerase Knockout in Myeloid Cells Predisposes Mice to Foam Cell Formation, Dyslipidemia, Lung Fibrosis, and Cardiac Dysfunction. [PDF]

Aging Cell
Gao Z, Yu Y, Wiggins D, Sevick-Muraca EM, Kolonin MG.   +4 more
europepmc   +1 more source

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

Advanced Science, EarlyView.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao, Hong‐Yi Zhao, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Kai Sun, Wei Gao, Duxin Sun   +11 more
wiley   +1 more source

7-T MRI intratumoral susceptibility signals reflect biomarker status in gliomas. [PDF]

Eur Radiol Exp
Yu F, Li K, Li Z, Zhou S, Chen W, Xiang C, Chen J, Zuo Z, Zhen Z, Chen W.   +9 more
europepmc   +1 more source

Fluorine‐Doping of Mesoporous TiO2 Enables Efficient Defect Passivation for High‐Efficiency and Stable Perovskite Solar Cells

Advanced Science, EarlyView.
We introduce an SF6 RIE plasma fluorination method for mesoporous TiO2, suppressing oxygen vacancies and improving charge extraction. The fluorinated TiO2 promotes uniform FAPbI3 film formation and enhances device performance under both one‐sun and indoor illumination.
Hye W. Chun, Sang Yeon Lee, Sang Eun Yoon, Gyeong G. Jeon, Veera Murugan Arivunithi, So Jeong Shin, Min Jun Choi, Byeongsu Kim, Min‐Ho Lee, Dohyeon Jeon, Taekyeong Kim, Jung‐Yong Lee, Jong H. Kim   +12 more
wiley   +1 more source

Integrated Radiomics Model Combining Diffusion Kurtosis Imaging and Dynamic Contrast-Enhanced MRI for Predicting TERT Promoter Mutation Status in Gliomas. [PDF]

Hum Mutat
Gao S, Zhang S, Wang Y, Chen L, Cao A, Du P.   +5 more
europepmc   +1 more source

Structural Insights Into Man9 Recognition by the HIV Antibody 2G12 Revealed by Paramagnetic NMR

Advanced Science, EarlyView.
The HIV gp120 glycoprotein displays Man9 oligomannose structures that are recognized by the neutralizing antibody 2G12. Detailed characterization of the binding epitope in solution is important for immunogen design but remains challenging, since the signals of the terminal mannoses from the three arms of Man9 (D1, D2, and D3) cannot be distinguished in
Adrián Silva‐Díaz, Paola Oquist‐Phillips, Noelia de la Cruz, Inés Lera‐Lasso, Laura Castañar, Javier Rojo, Javier Ramos‐Soriano, Ángeles Canales   +7 more
wiley   +1 more source

Decoding the significance of TERT gene in Polycystic Ovary Syndrome: From molecular mechanisms to emerging diagnostic and therapeutic strategies. [PDF]

J Ovarian Res
Balgote PJ, Nowshad F, Patnaik A, Sivaraman J.   +3 more
europepmc   +1 more source