Beyond the tumor microenvironment: a hierarchical immune-circuit model of immune checkpoint blockade resistance. [PDF]
Zhao X, Wang H, Liu Y, Cao L.
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Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang +16 more
wiley +1 more source
Tertiary lymphoid structures in gastrointestinal cancer: orchestrating tumour microenvironmental immune subcycles to elegantly amplify the cancer immunity cycle. [PDF]
Yin H, Qiao Y, Li X, Zhang J, Dong Q.
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ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas +4 more
wiley +1 more source
Clinical impact and therapeutic potential of tertiary lymphoid structures in melanoma. [PDF]
Carenza D +3 more
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ABSTRACT Posttransplant cyclophosphamide (PTCy) to prevent graft‐versus‐host disease (GVHD) improves outcomes in recipients of HLA mismatched unrelated donor (MMUD) allogeneic hematopoietic cell transplantation (allo HCT). Outcomes of MMUD HCT using PTCy in patients requiring reduced intensity or non‐myeloablative conditioning (RIC/NMA) are not well ...
Brian C. Shaffer +38 more
wiley +1 more source
Integrative Single-Cell and Spatial Transcriptomic Analysis Identifies a Tertiary Lymphoid Structure-Associated LAMP3<sup>+</sup>CCR7<sup>+</sup> mregDC Antigen-Presentation Program in Ovarian Cancer. [PDF]
Lu F +6 more
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Computed tomography findings of laryngeal lymphoma in two cats
Abstract We evaluated the computed tomography features of laryngeal lymphoma in two cats. In Cases 1 and 2, the mass was confined to the laryngeal region at the level of the thyroid cartilage. The masses were relatively well‐defined and round to oval, with no evidence of thyroid cartilage destruction.
Toshiyuki Tanaka +2 more
wiley +1 more source
Tertiary lymphoid structure topotypes in intrahepatic cholangiocarcinoma: spatial immunity, checkpoint-response associations, and therapeutic reprogramming. [PDF]
Yuan Z, Li X, Cheng Q, Gao J.
europepmc +1 more source

