Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello +20 more
wiley +1 more source
The CXCL13 hub in obesity-related metabolic inflammation: regulation of spatiotemporal heterogeneity and targeted strategies. [PDF]
Huang M, Chen X, Jiang Y, Liu T.
europepmc +1 more source
Carvacrol nanoemulsion as a novel approach to augment H9N2 influenza vaccine efficacy. [PDF]
Alanazi H +13 more
europepmc +1 more source
Morphometric Study of the Human Cadaveric Spleen: Dimensions, Shape Variations, and the Prevalence of Border Notches and Fissures. [PDF]
Musale AA +3 more
europepmc +1 more source
Inflammatory drivers of carotid atherosclerosis: signaling pathways, immune cells, and plaque stability. [PDF]
Li Y, Yang Y, Liu Y, Jiang J.
europepmc +1 more source
Metachronous bilateral renal cancer with immune checkpoint blockade-mediated eradication of bone metastasis: case report. [PDF]
Metodiev D +8 more
europepmc +1 more source
IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs [PDF]
Significance Ectopic clusters of immune cells that mimic the structure and function of secondary lymphoid organs are defined as tertiary lymphoid organs (TLOs). They have been observed at sites of chronic inflammation for decades, but their formation and function have remained enigmatic.
Christopher D Buckley +2 more
exaly +4 more sources
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Tertiary Lymphoid Organs: A Primer for Otolaryngologists
The Laryngoscope, 2020Objectives/HypothesisLymphoid neogenesis or the development of organised, de novo lymphoid structures has been described increasingly in chronically inflamed tissues. The presence of tertiary lymphoid organs (TLOs) has already been demonstrated to result in significant consequences for disease pathology, severity, prognosis and patient outcomes. Whilst
Sathish Paramasivan +3 more
openaire +2 more sources

