Results 211 to 220 of about 8,187 (242)

A Tertiary Lymphoid Structure-Derived Prognostic Signature Integrates Immune Microenvironment and Mutational Landscapes in Clear Cell Renal Cell Carcinoma. [PDF]

Hum Mutat
Zhou X, Zhao Z, Huang K, Ma G.
europepmc   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, Volume 13, Issue 45, 13 August 2026.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

ILC2s and their immune checkpoints in the antitumor response. [PDF]

J Immunother Cancer
Ciancaglini C, Santopolo S, Vacca P, Moretta L, Quatrini L.   +4 more
europepmc   +1 more source

SSR4 Sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, Volume 13, Issue 46, 17 August 2026.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Clinical and immunological significance of tertiary lymphoid structure maturation heterogeneity in brain metastases of lung adenocarcinoma. [PDF]

J Transl Med
Zhou C, Chen J, Wang Y, Chen L, Feng M, Li D, Gao Y, Li L, Chen X, Hao B, Wu X, Li Y, Yu H, Cao Y.   +13 more
europepmc   +1 more source

Immunological mechanistic action of intravenous BCG-mediated protection against tuberculosis. [PDF]

Cell Mol Life Sci
Choi S, Park J, Hong JJ, Shin SJ, Lee JM.   +4 more
europepmc   +1 more source

Single-cell transcriptomic insights into the immune heterogeneity of immune checkpoint inhibitors related organ toxicities. [PDF]

Front Immunol
Wen H, Qi Y, Song J, Yan X.
europepmc   +1 more source

Immune responses in aging adults. [PDF]

J Clin Invest
Weyand CM, Goronzy JJ.
europepmc   +1 more source

Spatial Immunology in Translation: Linking Immune Organisation to Therapeutic Outcome. [PDF]

Med Sci (Basel)
Bonilha CS.
europepmc   +1 more source

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Tertiary Lymphoid Organs: A Primer for Otolaryngologists

The Laryngoscope, 2020
Objectives/HypothesisLymphoid neogenesis or the development of organised, de novo lymphoid structures has been described increasingly in chronically inflamed tissues. The presence of tertiary lymphoid organs (TLOs) has already been demonstrated to result in significant consequences for disease pathology, severity, prognosis and patient outcomes. Whilst
Sathish Paramasivan, Alkis J. Psaltis, Peter‐John Wormald, Sarah Vreugde   +3 more
openaire   +2 more sources