Results 231 to 240 of about 58,085 (320)

Wnt and Treg-Associated Signaling Coordinate Mucosal Regeneration and MALT Formation in a Mouse Model of Chronic Colitis. [PDF]

Int J Mol Sci
Watanabe N, Kobayashi M, Kuriki T, Ebizuka Y, Hirata M, Mizuguchi R, Takimoto M, Yidan B, Luo M, Todoroki M, Lola MSG, Zou X, Jiang S, Kigata T, Shibutani M, Yoshida T, Omatsu T.   +16 more
europepmc   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, Volume 13, Issue 8, 9 February 2026.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

In Situ Vaccination by Tumor Ablation: Principles and Prospects for Systemic Antitumor Immunity. [PDF]

Vaccines (Basel)
Chikovani T, Magen E.
europepmc   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, Volume 13, Issue 8, 9 February 2026.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

Editorial: Advances in skin immunology. [PDF]

Front Immunol
Simionescu O.
europepmc   +1 more source

Regulatory T cell therapy in lung transplantation: bridging the gap from bench to bedside. [PDF]

Front Immunol
Li Q, Li G, Feng J, Zhang G.
europepmc   +1 more source

Insufficient Expression of the Autophagic Protein ATG16L1 Results in Accelerated Carcinogenesis Related to an Aberrant B Cell Response

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Autophagy‐related proteins (ATGs) regulate a great variety of cellular responses beyond autophagy. In cancer, the role of ATG proteins is central, as evidenced in spontaneous cancer emerging in animals lacking ATG proteins. Aim To determine whether ATG16L1 may be participating in tumorigenesis in colonic and oral mucosa and its ...
Daniela Mendiola, Betsaida Ortiz, Oscar Nieto, Marisol I. González, Danielle Vannan, Bertus Eksteen, Alejandro Martínez, Diego Mateos, Mónica G. Mendoza‐Rodríguez, Miriam Rodríguez‐Sosa, Luis I. Terrazas, José L. Reyes   +11 more
wiley   +1 more source

The Sunrise of Tertiary Lymphoid Structures in Cancer. [PDF]

Immunol Rev
Rochefort J, Marodon G, Teillaud JL, Dieu-Nosjean MC.   +3 more
europepmc   +1 more source

Tertiary Lymphoid Structures in Human Melanoma: Molecular Mechanisms and Therapeutic Opportunities. [PDF]

Cells
Ghajar-Rahimi G, Patel I, Yusuf N.
europepmc   +1 more source

Beyond bacterial defences: the role of lysozyme in cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang, Qian Dong, Fuchu He, Zhiwen Gu, Aihua Sun   +4 more
wiley   +1 more source