Results 41 to 50 of about 58,085 (320)

Long‐term B cell depletion associates with regeneration of kidney function

Immunity, Inflammation and Disease, 2021
Background Chronic kidney disease (CKD) is a common condition that increases mortality and the risk of cardiovascular and other morbidities regardless of underlying renal condition. Chronic inflammation promotes renal fibrosis.
Susanne V. Fleig, Franz F. Konen, Christoph Schröder, Jessica Schmitz, Stefan Gingele, Jan H. Bräsen, Svjetlana Lovric, Bernhard M. W. Schmidt, Hermann Haller, Thomas Skripuletz, Sibylle vonVietinghoff   +10 more
doaj   +1 more source

Stromal cells in chronic inflammation and tertiary lymphoid organ formation.

Annual Review of Immunology, 2015
Inflammation is an unstable state. It either resolves or persists. Why inflammation persists and the factors that define tissue tropism remain obscure. Increasing evidence suggests that tissue-resident stromal cells not only provide positional memory but also actively regulate the differential accumulation of inflammatory cells within inflamed tissues.
C. Buckley, F. Barone, S. Nayar, C. Bénézech, J. Caamaño   +4 more
semanticscholar   +3 more sources

Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity [PDF]

Frontiers in Immunology, 2016
Artery tertiary lymphoid organs (ATLOs) are atherosclerosis-associated lymphoid aggregates with varying degrees of complexity ranging from small T/B-cell clusters to well-structured lymph node-like though unencapsulated lymphoid tissues. ATLOs arise in the connective tissue that surrounds diseased arteries, i.e., the adventitia.
Changjun Yin, Changjun Yin, Sarajo Mohanta, Prasad Srikakulapu, Christian Weber, Christian Weber, Andreas Habenicht   +6 more
openaire   +4 more sources

Tertiary Lymphoid Structures in Cancer: Drivers of Antitumor immunity, immunosuppression, or Bystander Sentinels in Disease? [PDF]

, 2017
Secondary lymphoid organs are integral to initiation and execution of adaptive immune responses. These organs provide a setting for interactions between antigen-specific lymphocytes and antigen-presenting cells recruited from local infected or ...
Adachi, Ager, Ager, Aloisi, Andrian von, Ansel, Attridge, Avram, Banks, Bell, Bento, Bergomas, Bombardieri, Browning, Buckley, Bénézech, Calcinotto, Carragher, Carrega, Cañete, Chai, Chen, Cipponi, Colbeck, Coles, Contractor, Coppola, Coronella, de Chaisemartin, De Togni, Deteix, Di Caro, Dieu-Nosjean, Dieu-Nosjean, Drayton, Drayton, Eberl, Fan, Fava, Figenschau, Finkin, Foo, Furman, Furtado, Furtado, Förster, Galkina, Gallimore, Gantsev, García-Hernández, Gardner, Gatumu, Germain, Giraldo, Girard, Gobert, Goc, Goc, Gopal, Gräbner, Gu-Trantien, Hamanishi, Hindley, Hiraoka, Hjelmström, Johansson-Percival, Jones, Joshi, Joyce, Katakai, Kirk, Klages, Kocks, Kratz, Kroeger, Ladányi, Lee, Li, Liao, Lochner, Low, Lu, Luther, Luther, Luther, Marinkovic, Martinet, Martinet, Martinet, McMahon, McMullen, Mebius, Mebius, Mebius, Mebius, Meier, Messina, Motallebzadeh, Moussion, Moyron-Quiroz, Moyron-Quiroz, Muramatsu, Neyt, Nielsen, Nishikawa, Nzula, Ohl, Onder, Peske, Peters, Picker, Pitzalis, Randall, Randolph, Rangel-Moreno, Rangel-Moreno, Remark, Rennert, Roozendaal, Rosen, Ruddle, Sakaguchi, Sakai, Sawa, Scheu, Schmutz, Schneider, Schrama, Schrama, Scurr, Seleznik, Shields, Song, Stranford, Sun, Suzuki, Takatori, Teng, van de Pavert, van de Pavert, van de Pavert, Vermeij, Vondenhoff, Walter, Weinstein, Wengner, Winter, Yokota, Yoshida, Yoshida, Yoshida, Yu   +151 more
core   +11 more sources

Stroma cell priming in enteric lymphoid organ morphogenesis

Frontiers in Immunology, 2012
The lymphoid system is equipped with a network of specialized platforms located at strategic sites, which grant strict immune-surveillance and efficient immune responses.
Manuela eFerreira, Rita Gomes Domingues, Henrique eVeiga-Fernandes   +2 more
doaj   +1 more source

Perivascular adipose tissue inflammation in vascular disease [PDF]

, 2017
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core   +1 more source

Presence of Tertiary Lymphoid Organ in Nasal Inverted Papilloma Is Correlated with Eosinophil Infiltration and Local Immunoglobulin Production

International Archives of Allergy and Immunology, 2020
Introduction: Nasal inverted papilloma (NIP) is a benign tumour with multiple inflammatory cell infiltration. Tertiary lymphoid organs (TLOs) support local antibody production and play important roles in airway inflammation. However, the evidence of TLOs
Qing Bao, Xuexue Guo, C. Cao, Qianying Li, Lin Sun, X. Ye, Liyue Li, Jun-Chao Dong, Yifang Gao, H. Chen, C. Li   +10 more
semanticscholar   +1 more source

Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma

Frontiers in Immunology, 2012
In this communication, the contribution of stromal, or non-hematopoietic, cells to the structure and function of lymph nodes (LNs), as canonical secondary lymphoid organs (SLOs), is compared to that of tertiary lymphoid tissue or organs (TLOs), also ...
Sharon eStranford, Nancy H. Ruddle
doaj   +1 more source

Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization [PDF]

, 2009
In this report we describe a transplantation system where embryonic spleens are grafted into adult hosts. This model can be used to analyze the cellular and molecular requirements for the development and organization of splenic microenvironments.Whole ...
Aloisi, Bajenoff, Bekiaris, Bekiaris, Brendolan, Chen, Cupedo, Cupedo, Cupedo, Drayton, Eberl, Fan, Fu, Fu, Futterer, Honda, Kim, Kim, Kim, Kim, Kim, Kratz, Link, Luther, Luther, Luther, Mackay, Mebius, Meier, Ngo, Ngo, Nolte, Rennert, Rossi, Scandella, Sun, Togni, Veiga-Fernandes, Vondenhoff, Wang, White, Withers, Yokota, Yoshida   +43 more
core   +2 more sources

Tertiary Lymphoid Organs in Cancer Immunology: Mechanisms and the New Strategy for Immunotherapy

Frontiers in Immunology, 2019
The immune system plays pivotal roles in the occurrence and progression of cancers. As blockade of immune-checkpoint has been proven effective at improving anti-tumor immune response in multiple tumor types, the tumor immunotherapy still faces many ...
Liangbin Lin, Xiang Hu, Huiyuan Zhang, Hongbo Hu   +3 more
doaj   +1 more source