Results 91 to 100 of about 9,713 (217)

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

The Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu, Ivan Varga, Răzvan Costin Tudose   +2 more
wiley   +1 more source

Epididymitis promotes formation of tertiary lymphoid organs in the cauda epididymidis

Mucosal Immunology
Uropathogenic Escherichia coli is a common pathogen that affects the cauda epididymidis, causing interstitial edema, epithelial damage, leukocyte infiltration, and fibrosis. Despite antibiotic treatment, up to 20 % of patients develop abscesses in the cauda epididymidis, and 40 % experience low sperm counts.
Hiba Hasan, Christiane Pleuger, Dingding Ai, Sudhanshu Bhushan, Eva Wahle, Tara Procida-Kowalski, Qunxiong Zeng, Rukmali Wijayarathna, Claire Xin Sun, Yong-Gang Duan, Daniela Fietz, Marek Bartkuhn, Hans-Christian Schuppe, Adrian Pilatz, Kate L. Loveland, Andreas Meinhardt, Mark P. Hedger, Monika Fijak   +17 more
openaire   +2 more sources

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Lymphoid stroma in all its states

Frontiers in Immunology
Stromal cells are found in all tissues of the body. Among them, lymphoid stromal cells (LSCs) correspond to the cell subsets found in secondary and tertiary lymphoid organs.
Nicolas Barbier, Nicolas Barbier, Valentin Isen, Karin Tarte, Karin Tarte, David Roulois   +5 more
doaj   +1 more source

Ectopic Lymphoid Structures: powerhouse of autoimmunity

Frontiers in Immunology, 2016
Ectopic lymphoid structures (ELS) often develop at sites of inflammation in target tissues of autoimmune diseases such as rheumatoid arthritis, Sjögren’s syndrome, multiple sclerosis, myasthenia gravis and systemic lupus erythematosus.
Elisa Corsiero, Alessandra Nerviani, Michele Bombardieri, Costantino Pitzalis   +3 more
doaj   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

T Cell Plasticity in Systemic Lupus Erythematosus Revealed by Large‐Scale T Cell Receptor Repertoire and Transcriptome Studies

Arthritis &Rheumatology, EarlyView.
Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi, Masahiro Nakano, Kaitlyn A. Lagattuta, Mineto Ota, Hiroaki Hatano, Haruka Takahashi, Takahiro Itamiya, Hajime Inokuchi, Soumya Raychaudhuri, Tomohisa Okamura, Keishi Fujio, Kazuyoshi Ishigaki   +11 more
wiley   +1 more source

B cells in the formation of tertiary lymphoid organs in autoimmunity, transplantation and tumorigenesis

Current Opinion in Immunology, 2019
Tertiary lymphoid organs named also tertiary lymphoid structures (TLS) often occur at sites of autoimmune inflammation, organ transplantation and cancer. Although the mechanisms for their formation/function are not entirely understood, it is known that TLS can display features of active germinal centres supporting the proliferation and differentiation ...
Elisa Corsiero, Francesca Romana Delvecchio, Michele Bombardieri, Costantino Pitzalis   +3 more
openaire   +3 more sources

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma

OncoImmunology, 2018
T follicular helper cells (Tfh) play crucial roles in the development of humoral immunity. In the B cell-rich germinal center of lymphoid organs, they select for high-affinity B cells and aid in their maturation.
Kevin W Ng, Erin A Marshall, Katey SS Enfield, Spencer D Martin, Katy Milne, Michelle E Pewarchuk, Ninan Abraham, Wan L Lam   +7 more
doaj   +1 more source