Results 191 to 200 of about 9,713 (217)

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang, Chung‐I Li, Rui Xin, Jijun Tang, Yan Guo   +4 more
wiley   +1 more source

The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures

Reviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria, Francesco Branda, Giancarlo Ceccarelli, Fabio Scarpa, Massimo Ciccozzi, Alessandro Russo   +5 more
wiley   +1 more source

The biological characteristics of tertiary lymphoid structures in head and neck cancer. [PDF]

Front Immunol
Bai S, Wei Y, Liu F, Sun H, Zeng X, Zhang P.   +5 more
europepmc   +1 more source

Predicting survival in oral squamous cell carcinoma via integrated analysis of tumor budding and tertiary lymphoid structures. [PDF]

Front Oncol
Xiang Z, Huang Y, Yun B, Li D, Liu F, Liu J, Xie N, Zhuang Z, Hou J, Wang C.   +9 more
europepmc   +1 more source

FOXP3⁺ Cells in Tertiary Lymphoid Structures Have Adverse Impact on Overall Survival in Patients with Gastric Cancer. [PDF]

Med Sci (Basel)
Paparella Karaman A, Ivanović T, Mustapić K, Vukojević K, Minarik L, Glavina Durdov M, Đolonga P.   +6 more
europepmc   +1 more source

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Tertiary Lymphoid Organs: A Primer for Otolaryngologists

The Laryngoscope, 2020
Objectives/HypothesisLymphoid neogenesis or the development of organised, de novo lymphoid structures has been described increasingly in chronically inflamed tissues. The presence of tertiary lymphoid organs (TLOs) has already been demonstrated to result in significant consequences for disease pathology, severity, prognosis and patient outcomes. Whilst
Sathish Paramasivan, Alkis J. Psaltis, Peter‐John Wormald, Sarah Vreugde   +3 more
openaire   +2 more sources

Adventitial tertiary lymphoid organ classification in human atherosclerosis

Cardiovascular Pathology, 2018
Atherosclerosis is a chronic inflammatory disease of the arterial wall. Adjacent to lamina intima lesion progression, a cellular compound develops in the lamina adventitia, defined as tertiary lymphoid organs (TLO) in mice. But in human system, it remains unknown whether these adventitial cellular accumulations represent these highly organized ...
Mohammadreza, Akhavanpoor, Christian A, Gleissner, Hamidreza, Akhavanpoor, Felix, Lasitschka, Andreas O, Doesch, Hugo A, Katus, Christian, Erbel   +6 more
openaire   +2 more sources

Tertiary Lymphoid Structures Among the World of Noncanonical Ectopic Lymphoid Organizations

2018
Tertiary lymphoid structures (TLOs), also known as ectopic lymphoid structures, are associated with chronic infections and inflammatory diseases. Despite their association with pathology, these structures are actually a normal, albeit transient, component of the immune system and facilitate local immune responses that are meant to mitigate inflammation
Aaron, Silva-Sanchez, Troy D, Randall, Selene, Meza-Perez   +2 more
openaire   +2 more sources

Synthesis of Functional Tertiary Lymphoid Organs

2016
The regeneration of functional immune organ will be one of major focus in future immunology research. It will be an useful tool which induces efficient immune responses in the body on demand and offers effective ways to restore the immune status and treat uncontrollable obstinate diseases such as cancer, autoimmune diseases, severe infection and immuno-
Yuka Kobayashi, Koichi Kato, Makoto Nakamura, Takeshi Watanabe   +3 more
openaire   +1 more source

Development and organization of the secondary and tertiary lymphoid organs: Influence of microbial and food antigens

Clinical Immunology, Endocrine & Metabolic Drugs, 2018
Background: Secondary lymphoid organs (SLO) are distributed in many districts of the body and, especially, lymph nodes, spleen and gut-associated lymphoid tissue are the main cellular sites. On the other hand, tertiary lymphoid organs (TLO) are formed in response to inflammatory, infectious, autoimmune and neoplastic events. Developmental Studies:
Magrone T., Jirillo E.
openaire   +3 more sources