Inflammation and Immune Mechanisms in Atherosclerosis. [PDF]
Wan Z, Xu X, Zhu G.
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POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley +1 more source
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello +20 more
wiley +1 more source
Global research landscape and emerging trends of tertiary lymphoid structures in autoimmune diseases: a bibliometric analysis. [PDF]
Wang J +6 more
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Tertiary lymphoid structures in gastrointestinal cancer: orchestrating tumour microenvironmental immune subcycles to elegantly amplify the cancer immunity cycle. [PDF]
Yin H, Qiao Y, Li X, Zhang J, Dong Q.
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Germinal center responses at barrier organ sites. [PDF]
Foster WS, Nowosad CR.
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Tertiary Lymphoid Organs: A Primer for Otolaryngologists
The Laryngoscope, 2020Objectives/HypothesisLymphoid neogenesis or the development of organised, de novo lymphoid structures has been described increasingly in chronically inflamed tissues. The presence of tertiary lymphoid organs (TLOs) has already been demonstrated to result in significant consequences for disease pathology, severity, prognosis and patient outcomes. Whilst
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Adventitial tertiary lymphoid organ classification in human atherosclerosis
Cardiovascular Pathology, 2018Atherosclerosis is a chronic inflammatory disease of the arterial wall. Adjacent to lamina intima lesion progression, a cellular compound develops in the lamina adventitia, defined as tertiary lymphoid organs (TLO) in mice. But in human system, it remains unknown whether these adventitial cellular accumulations represent these highly organized ...
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Tertiary lymphoid organs contribute to kidney allograft rejection
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Tertiary Lymphoid Structures Among the World of Noncanonical Ectopic Lymphoid Organizations
2018Tertiary lymphoid structures (TLOs), also known as ectopic lymphoid structures, are associated with chronic infections and inflammatory diseases. Despite their association with pathology, these structures are actually a normal, albeit transient, component of the immune system and facilitate local immune responses that are meant to mitigate inflammation
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