Tertiary lymphoid structure tls - Open Access .click

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Abstract 3205: Artificial intelligence (AI) -powered H&E whole-slide image (WSI) analysis of tertiary lymphoid structure(TLS) to predict response to immunotherapy in non-small cell lung cancer (NSCLC)

Cancer Research
Background: The efficacy of ICIs in treating NSCLC is limited to a subset of patients, necessitating reliable predictive biomarkers. TLSs within the tumor microenvironment have emerged as potential indicators. This study aims to investigate the association between an AI-powered TLS analysis and treatment response of
Young Kwang Chae +6 more
openaire +1 more source

Tertiary lymphoid structure formation induced by LIGHT-engineered and photosensitive nanoparticles-decorated bacteria enhances immune response against colorectal cancer.

Biomaterials
Tertiary lymphoid structures (TLSs) are known to enhance the prognosis of patients with colorectal cancer (CRC) by fostering an immunologically active tumor microenvironment (TME).
Li-kuan Hu +9 more
semanticscholar +1 more source

TLR agonists promote formation of Tertiary Lymphoid Structure and improve anti-glioma immunity.

Neuro-Oncology
BACKGROUND Glioma, characterized by limited lymphocytic infiltration, constitutes an "immune-desert" tumor displaying insensitivity to various immunotherapies.
Shaoping Shen +13 more
semanticscholar +1 more source

702 Tertiary lymphoid structures (TLS) observed in non-small cell lung cancer (NSCLC) tumors treated with pulsed electric fields