Results 191 to 200 of about 3,969,489 (270)

Spatial architecture of tertiary lymphoid structures represents an independent prognostic dimension in hepatocellular carcinoma. [PDF]

J Immunother Cancer
Liu W, Zhu C, Cui Z, Shi J, Zhang B, Xiong A, Wang L, Gao Q, Ding G, Liu X.   +9 more
europepmc   +1 more source

Warm autoimmune haemolytic anaemia in Taiwan: A population‐based study of epidemiology, treatment patterns, survival and healthcare utilisation (2017–2022)

British Journal of Haematology, EarlyView.
Summary To describe the epidemiology, treatment patterns, overall survival (OS) and healthcare resource use among patients with warm autoimmune haemolytic anaemia (wAIHA) in Taiwan, adult patients with ≥1 diagnosis code for autoimmune haemolytic anaemia (AIHA) with record of wAIHA‐related treatments between 2017 and 2022 were retrospectively identified
Hsiao‐Wen Kao, Shu‐Chen Chang, Dae Young Yu, Tse‐Chih Chou, I‐Ching Tsai, Ann Leon, Alexis Krumme, David Bin‐Chia Wu, Chee Jen Chang   +8 more
wiley   +1 more source

Tertiary lymphoid structures in breast cancer: formation, immune functions and clinical implications. [PDF]

Front Immunol
Dong W, Ai S, Shen X, Yao Y.
europepmc   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

Global research landscape and emerging trends of tertiary lymphoid structures in autoimmune diseases: a bibliometric analysis. [PDF]

Front Immunol
Wang J, Zhao Y, Chen X, Dong T, Feng Z, Zhang Z, Li Z.   +6 more
europepmc   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

Commentary: Characteristics of tertiary lymphoid structures in prostate cancer and the impact of neoadjuvant therapy on their formation and maturation. [PDF]

Front Immunol
Wan Q, Chen W, Yang J, Qin Y, Li H, Li J, Huang Y, Liu Y, Ding M.   +8 more
europepmc   +1 more source

Lung Cancer Brain Metastasis: Brain Microenvironmental Adaptation, Therapeutic Resistance and Translational Strategies

Cancer Science, EarlyView.
Lung cancer brain metastasis is shaped by dynamic crosstalk among tumor cells, the blood–brain barrier, glial and immune cells, neurons, and metabolic niches. This review integrates these mechanisms with therapeutic resistance, translational models, CNS delivery, and multidisciplinary treatment strategies.
Jun Yang, Junyi Xiong, Li Ying, Yanyang Zeng, Ziqiang Ouyang, Mei Liu, Meihua Li   +6 more
wiley   +1 more source

Metabolite-driven dysfunction of intratumoral tertiary lymphoid structures: single-cell and spatial omics perspectives on cancer immune escape. [PDF]

Front Immunol
Wang Y, Li Y, Wei S, Ding S.
europepmc   +1 more source

Spatiotemporal CD8+ T‐Cell Dynamics: Clonal Replacement and Expansion as Determinants of Sustainable Antitumor Response

Cancer Science, EarlyView.
Durable antitumor immunity depends on continuous clonal replacement: immune checkpoint inhibitors that drive sustainable, polyclonal mobilization of T‐cell clones from tumor‐draining lymph nodes sustain tumor control, whereas limited, oligoclonal mobilization allows pre‐existing clones to become exhausted, leading to immune escape.
Satoshi Ueha, Hiroyasu Aoki, Munetomo Takahashi, Shigeyuki Shichino, Kouji Matsushima   +4 more
wiley   +1 more source