Results 201 to 210 of about 3,969,489 (270)

Tertiary lymphoid structures in genitourinary cancers: a comprehensive review. [PDF]

Front Oncol
Abreu A, Viera Plasencia A, Iribarren M, Wegner C, Nuraj J, Davicioni E, Bahmad HF, Shahait M.   +7 more
europepmc   +1 more source

Spatial Atlas of Small Cell Lung Carcinoma Reveals Intratumoral Tumor‐State Heterogeneity and an MMP12+ Macrophage Niche

Cancer Science, EarlyView.
Spatial transcriptomic profiling of SCLC revealed marked intratumoral heterogeneity, including coexisting neuroendocrine and non‐neuroendocrine states and spatially heterogeneous hypoxia, and identified an MMP12+ macrophage population enriched at hypoxic and necrotic tumor interfaces.
Naozane Nomura, Naoe Jimbo, Takaaki Nakanishi, Yukinobu Ito, Maki Sakaguchi, Daichi Maeda, Hiroko Ikeda, Tsukasa Ueda, Hayato Koba, Seiji Yano, Isao Matsumoto, Patrick Micke, Takayuki Kodama, Manabu Shigeoka, Yu‐ichiro Koma, Masafumi Horie   +15 more
wiley   +1 more source

Tertiary Lymphoid Structures as Predictors of Recurrence in Colorectal Cancer: Development and Validation of a Machine Learning-Based Scoring Model. [PDF]

Cancer Med
Lei XH, Li R, Wang DM, Liu L, Wang ZQ, Li HJ.   +5 more
europepmc   +1 more source

Single‐Cell and Spatial Analysis Reveal the Differences Between Left‐Sided and Right‐Sided Colorectal Cancer

Cell Proliferation, EarlyView.
Single‐cell and spatial analysis revealed distinct CRC microenvironments by tumour laterality. Right‐sided tumours showed enhanced germinal centre B cells, CXCL13+ T cells, and organized TLS‐immune crosstalk via CCL19/21‐CCR7, suggesting better immunotherapy response.
Zongnai Zhang, Jiaqi Xu, Yingchao Wu, Tao Liu, Junling Zhang, Mai Zhou, Jie Qiao, Heng Pan, Xin Wang   +8 more
wiley   +1 more source

The Prognostic Significance of Tertiary Lymphoid Structures in Head and Neck Cancers: A Systematic Review and Meta-Analysis. [PDF]

J Oral Pathol Med
de Morais EF, da Costa BC, Mäkitie A, Coletta RD, Almangush A.   +4 more
europepmc   +1 more source

Charting the course of Sjögren's disease: A historical analysis of scientific progress

European Journal of Oral Sciences, EarlyView.
Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali, Fabiola Reis de Oliveira, Denise Cantarelli Machado, Moisés Evandro Bauer   +3 more
wiley   +1 more source

Tertiary lymphoid structures in breast cancer: Mechanistic insights, subtype-specific patterns, and therapeutic implications. [PDF]

World J Surg Oncol
Liang Y, Wu K, Pan L, Jia M, Zhang W, Zhang X, Gao J.   +6 more
europepmc   +1 more source

Simultaneous modification of Thermotoga maritima encapsulin subunits to produce multivalent nanoparticle vaccines for non‐typhoidal Salmonella enterica

The FEBS Journal, EarlyView.
This study investigates the modularity of encapsulin—a protein nanoparticle—by simultaneously inserting up to four distinct Salmonella epitopes within the encapsulin subunit. The encapsulin variants were transiently expressed in plants where they assembled into nanoparticles; however, their accumulation and stability varied depending on the ...
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source

Targeting IFN-I driven tertiary lymphoid structures halts B cell-mediated bone loss in periodontitis. [PDF]

Int J Oral Sci
Lu J, Wu X, Xiong Z, Zhang J, Yang H, Liu F, Luo L.   +6 more
europepmc   +1 more source