Results 201 to 210 of about 13,821 (239)

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

Neoadjuvant Immunotherapy Promotes the Formation of Mature Tertiary Lymphoid Structures in a Remodeled Pancreatic Tumor Microenvironment. [PDF]

Cancer Immunol Res
Sidiropoulos DN, Shin SM, Wetzel M, Girgis AA, Bergman D, Danilova L, Perikala S, Shu D, Montagne JM, Deshpande A, Leatherman J, Dequiedt L, Jacobs V, Ogurtsova A, Mo G, Yuan X, Lvovs D, Stein-O'Brien G, Yarchoan M, Zhu Q, Harper EI, Weeraratna AT, Kiemen AL, Jaffee EM, Zheng L, Ho WJ, Anders RA, Fertig EJ, Kagohara LT.   +28 more
europepmc   +1 more source

Diagnostic potential of B‐cell translocation gene 2 in IgA nephropathy: Insights from molecular mechanisms

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Diagnostic value of BTG2 and its immunoregulatory mechanism in IgAN. This study reveals that BTG2 improves immune microenvironment dysregulation, attenuates inflammation, and reduces fibrosis by promoting the expansion of T follicular helper cells, inducing macrophage polarization toward an M2 anti‐inflammatory phenotype, and inhibiting the TGF‐β1 ...
Min Kou, Mo Dan, Juan Cheng, Sheng Ge, Ruimin Ren   +4 more
wiley   +1 more source

Dynamic remodeling of tertiary lymphoid structures in response to cancer therapy: a recent review. [PDF]

Cancer Immunol Immunother
Tan C, Huang J, Gao N, Wu B, Juliet M, Xiao J, Hu J, Liu P, Chen J.   +8 more
europepmc   +1 more source

Mapping B cells and the immune landscape of tertiary lymphoid structures reveals their clinical impact in neuroblastoma. [PDF]

J Immunother Cancer
Melaiu O, Chierici M, Gragera P, Lazzaro N, Petrilli LL, Wienke J, Bergsma FJ, Verhoeven BM, De Stefanis C, D'Oria V, Benedetti MC, Barillari G, Alaggio R, De Ioris MA, Vinci M, Baryawno N, Carsetti R, Jurman G, Molenaar JJ, Locatelli F, Fruci D.   +20 more
europepmc   +1 more source

Macrophages in tertiary lymphoid structures promote apoptosis of ATF4-positive gastric cancer cells via IL18. [PDF]

J Transl Med
Zhou L, Li X, Wu J, Zheng T, Lin M, Ou Y, Zhou H, Mo S, Han X, Xiang J, Gong W.   +10 more
europepmc   +1 more source

Role of tertiary lymphoid structures in the tumour microenvironment and immunotherapy response of renal cell carcinoma. [PDF]

Clin Transl Med
Yang L, Shangguan W, Li W, Huang W, Li Z, Sun B, Ma C, Yang X, Cheng B, Wu P.   +9 more
europepmc   +1 more source

TCF1+CD4+ T cells and microglia co-orchestrate tertiary lymphoid structures to enhance prognosis and immunotherapy in non-small cell lung cancer with brain metastases. [PDF]

EBioMedicine
Yu Q, Liao R, Zheng H, Li L, Huang Y, Tao Y, Deng R, He H, Yu L, Lin J, Huang S, Zhang X, Xu Z, Yang Z, Peng Y.   +14 more
europepmc   +1 more source

Spatial distribution analysis of tertiary lymphoid structures in esophageal squamous cell carcinoma predicts patient survival and response to neoadjuvant chemo-immunotherapy. [PDF]

J Transl Med
Wang L, Li J, Ao Y, Yu Y, Zhai J, Zhang Y, Wu L, Hao J, Hu Y, Wang Q, Yin F, Liu T.   +11 more
europepmc   +1 more source

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Tertiary lymphoid structures in cancer

Science, 2022
Tertiary lymphoid structures in cancer Tertiary lymphoid structures (TLSs) are lymphoid formations that are found in nonlymphoid tissues. TLS can develop in inflamed tissues and are associated with chronic inflammatory disorders, autoimmunity, and cancer. In the setting of tumors, TLSs facilitate the influx of immune cells into the tumor site
Ton N. Schumacher, Daniela S. Thommen
openaire   +2 more sources