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Cellular and Vascular Components of Tertiary Lymphoid Structures
2018Inflammatory immune cells recruited at the site of chronic inflammation form structures that resemble secondary lymphoid organs (SLO). These are characterized by segregated areas of prevalent T- or B-cell aggregation, differentiation of high endothelial venules, and local activation of resident stromal cells, including lymphatic endothelial cells.
Christopher George, Mueller +3 more
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Tertiary Lymphoid Structures Among the World of Noncanonical Ectopic Lymphoid Organizations
2018Tertiary lymphoid structures (TLOs), also known as ectopic lymphoid structures, are associated with chronic infections and inflammatory diseases. Despite their association with pathology, these structures are actually a normal, albeit transient, component of the immune system and facilitate local immune responses that are meant to mitigate inflammation
Aaron, Silva-Sanchez +2 more
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The Evolving Landscape of Bladder Tertiary Lymphoid Structures
Journal of Urology, 2023Madhuri, Koti, D Robert, Siemens
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Tertiary lymphoid structures and B lymphocytes in cancer prognosis and response to immunotherapies
OncoImmunology, 2021Stephen Nutt +2 more
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Tertiary lymphoid structures as hubs of antitumour immunity
Nature Reviews Cancer, 2023Gabriela Sarti Kinker +1 more
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Tertiary Lymphoid Structures and Immunotherapy: Challenges and Opportunities
Tertiary lymphoid structures (TLS) are accumulations of lymphoid cells that arise in ectopic sites through the process of lymphoid neogenesis in chronic inflammation in autoimmunity, microbial infections, organ rejection, aging, and cancer. Their cellular composition and function and regulation via members of the lymphotoxin (LT)/tumor necrosis factor (openaire +2 more sources
Tertiary Lymphoid Structures: A Potential Biomarker for Anti-Cancer Therapy
Cancers, 2022Yue Zeng, Ji'An Zou, Zeng Yue
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