Results 21 to 30 of about 5,712,508 (248)
Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]
, 2000 Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core +1 more source
Testicular germ cell tumor genomics [PDF]
Current Opinion in Urology, 2017 Testicular germ cell tumors (TGCTs) are a model for curable cancer because of exquisite chemosensitivity and incorporation of multimodal therapy. Nevertheless, our ability to predict metastases in early-stage disease and responders to chemotherapy in advanced disease is limited. Treatment options for cisplatin-resistant disease are sparse.
Solomon L, Woldu +2 more
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Cell Reports, 2017 Summary: Testicular germ cell tumors (TGCTs) are among the most responsive solid cancers to conventional chemotherapy. To elucidate the underlying mechanisms, we developed a mouse TGCT model featuring germ cell-specific Kras activation and Pten ...
Timothy M. Pierpont +15 more
doaj +1 more source
Testicular Tumors: A 15-Year Archive Review and Histopathological Evaluation
Journal of Contemporary Medicine, 2021 Aim: Testicular tumors are one of the most common malignancies in men in the age group of 15-40 years, although they are rarely observed. In our study, it was aimed to evaluate their histopathological features by retrospectively examining of the cases ...
Akgül Arıcı +5 more
doaj +1 more source
European Urology Open Science, 2022 Incidental detection of urogenital tumors has increased in recent decades owing to the greater use of ultrasonography and cross-sectional imaging. For patients with low-risk prostate cancer or small renal masses, active surveillance represents a valid ...
Manolis Pratsinis +22 more
doaj +1 more source
Emerging Prognostic Biomarkers in Testicular Germ Cell Tumors: Looking Beyond Established Practice
Frontiers in Oncology, 2018 Testicular germ cell tumors are unique among solid cancers. Historically, this disease was deadly if progressed beyond the stage I. The implementation of cisplatin-based chemotherapy regimens has drastically changed the clinical outcome of metastatic ...
Michal Chovanec +7 more
doaj +1 more source
Burned-Out Testicular Tumor: A Case Report
Case Reports in Oncology, 2011 Germ cell tumors constitute the majority of all testicular tumors, which are relatively rare overall and are mainly encountered in young adults and teenagers.
N. Balalaa, M. Salman, W. Hassen
doaj +1 more source
Urology Case Reports, 2020 Testicular cancer accounts for 1% of male neoplasms, the most common histology is bilateral presentation is reported in 1–2% of cases, and germ cell tumor histology represents 90–95% of cases. Especifically, choriocarcinoma as a pure component represents
Salgado Sánchez Luis Eduardo +4 more
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An Overview of Testicular Germ Cell Tumors
Archives of Pathology & Laboratory Medicine, 2007 Abstract Context. —More than 90% of testicular neoplasms originate from germ cells. Testicular germ cell tumors (GCTs) are a heterogeneous group of neoplasms with diverse histopathology and clinical behavior. Objective.
Armita, Bahrami +2 more
openaire +2 more sources
Исследования и практика в медицине, 2019 Testicular cancer is a rare malignant tumor. In the structure of general cancer incidence, this nosology accounts for about 1–1.5% of cases. Among this pathology, about 90–95% is due to testicular germ cell tumors.
T. V. Ustinova +10 more
doaj +1 more source