Results 41 to 50 of about 5,712,508 (248)

Lost in descent: Complications of cryptorchidism

Radiology Case Reports, 2023
Cryptorchidism is a relatively common and important clinical entity and can lead to an array of downstream complications if it is not corrected in a timely manner, most notably with the development of testicular germ cell tumors.
Lauren Facer, MD, Theresa Pham, MD, Douglas Rogers, MD   +2 more
doaj   +1 more source

Prognostic factors in seminomas with special respect to HCG: Results of a prospective multicenter study [PDF]

, 1999
Objective: In a prospective multicenter trial, it was our intention to elucidate clinical prognostic factors of seminomas with special reference to the importance of human chorionic gonadotropin (HCG) elevations in histologically pure seminomas. Methods:
Dieckmann, K. P., Mann, K., Weissbach, L., Löhrs, U., Bussar-Maatz, R., Schubert, G. E., Fassbinder, J., Hartmann, M.   +7 more
core   +1 more source

Abstract 3703: A genomic characterization of testicular germ cell tumor immune microenvironment

, 2017
Testicular germ cell tumors (TGCT) are a histologically diverse set of tumors and the most common cancer type in young men. As part of the TCGA effort, we analyzed tumors from 133 patients including 4 patients with asynchronous double primary TGCTs (137 ...
Benjamin Vincent, Charles M. Perou, Daniel P. Hollern, Katie Hoadley, TCGA Testicular Germ Cell Tumor Analysis Working Group   +4 more
core   +1 more source

Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]

, 2008
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
Baker, P.J., Guillou, F., Abel, M.H., Verhoeven, G., De Gendt, K., Guillou, Florian Jean Louis, Charlton, H.M., Monteiro, A., O'Shaughnessy, P.J.   +8 more
core   +1 more source

Circulating Tumor Cells in Patients with Testicular Germ Cell Tumors [PDF]

Clinical Cancer Research, 2014
Abstract Purpose: Germ cell tumors (GCTs) represent the most frequent malignancies among young men, but little is known about circulating tumor cells (CTCs) in these tumors. Considering their heterogeneity, CTCs were investigated using two independent assays targeting germ cell tumor and epithelial cell–specific markers, and results ...
P. Nasta y, C. Ruf, P. Becker, N. Bednarz-Knoll, M. Stoupiec, R. Kavsur, H. Isbarn, C. Matthies, W. Wagner, D. Hoppner, M. Fisch, C. Bokemeyer, S. Ahyai, F. Honecker, S. Riethdorf, K. Pantel   +15 more
openaire   +2 more sources

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Radiotherapy in testicular germ cell tumours – a literature review [PDF]

, 2017
Testicular germ cell tumours (GCT) represent about 1–2% of malignant in men. The essential therapeutic option for early-stage GCT is radical orchiectomy (RO), except in situ ations that require immediate chemotherapy in patients with a massive ...
Pawel Wiechno, Magdalena Golawska, Joanna Jonska-Gmyrek, Grazyna Poniatowska, Tomasz Demkow, Maria Kowalska, Agnieszka Zolciak-Siwinska, Wojciech Michalski, Beata Kotowicz, Piotr Peczkowski   +9 more
core   +1 more source

Tumores testiculares na infância

Revista do Colégio Brasileiro de Cirurgiões
Testicular and paratesticular prepuberal tumors are rare. They represent around 1% of the total of tumors of infancy. They subdivide in 2 groups: germ cells tumors and non germ cells tumors, being able to occur in all the ages, and about 75% are ...
Roni Leonardo Teixeira, Aírton Rossini, Neiva Pereira Paim   +2 more
doaj   +1 more source

Evaluation of therapeutic effects of D‐limonene following orchiopexy in the rat model of cryptorchidism

Animal Models and Experimental Medicine, EarlyView.
D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala, Mohammadjavad Rezaei‐Varmaziar, Majid Taati, Ali Soleimanzadeh, Abbas Raisi, Farshid Davoodi, Amir Ali Shahbazfar   +6 more
wiley   +1 more source

Epigenetics and Testicular Cancer: Bridging the Gap Between Fundamental Biology and Patient Care

Frontiers in Cell and Developmental Biology, 2022
Testicular cancer is the most common solid tumor affecting young males. Most testicular cancers are testicular germ cell tumors (TGCTs), which are divided into seminomas (SGCTs) and non-seminomatous testicular germ cell tumors (NSGCTs).
Alina-Teodora Nicu, Alina-Teodora Nicu, Cosmin Medar, Mariana Carmen Chifiriuc, Mariana Carmen Chifiriuc, Mariana Carmen Chifiriuc, Mariana Carmen Chifiriuc, Gratiela Gradisteanu Pircalabioru, Liliana Burlibasa, Liliana Burlibasa   +9 more
doaj   +1 more source