Results 31 to 40 of about 5,712,508 (248)

Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]

, 2010
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H., Verhoeven, G., De Gendt, K., Monteiro, A., O'Shaughnessy, P.J.   +4 more
core   +1 more source

Androgen action via testicular arteriole smooth muscle cells is important for leydig cell function, vasomotion and testicular fluid dynamics [PDF]

, 2010
Regulation of blood flow through the testicular microvasculature by vasomotion is thought to be important for normal testis function as it regulates interstitial fluid (IF) dynamics which is an important intra-testicular transport medium.
Bergh, A., Sigrid Kilter, Richard M. Sharpe, Philippa T K Saunders, Lindsey Moffat, Sharpe, R.M., Welsh Michelle, Welsh, M., Anders Bergh, Philippa T. K. Saunders, Atanassova Nina, Saunders Philippa T. K., Atanassova, N., Smith, Lee B., Richard M Sharpe, Bergh, Anders, Bergh, Anders,, Kilter Sigrid, Sharpe, Richard M, Michelle Welsh, Sharpe Richard M., Moffat Lindsey, Lee B. Smith, Sharpe, Richard M., Moffat, Lindsey, Smith, L.B., Lee B Smith, Saunders, P.T.K., Kilter, Sigrid, Bergh Anders, Saunders, Philippa T. K.; id_orcid, Welsh, Michelle, Saunders, Philippa TK, Nina Atanassova, Smith Lee B., Smith, Lee B, Moffat, L., Kilter, S., Kilter, Sigrid,, Atanassova, Nina   +39 more
core   +1 more source

Socio-economic inequalities in testicular cancer survival within two clinical studies. [PDF]

, 2012
BACKGROUND: Testicular cancer is the most common cancer in men under 35 years of age, and has the highest survival for adult male malignancies. Despite the fact that survival is very high, there is evidence that survival differs between socio-economic ...
Read, Graham, Michel P. Coleman, Stenning, Sally, Cooper, Nicola, Coleman, Michel P., Graham Read, Parmar, Mahesh KB, Oliver, Tim, Mathew R. Sydes, Malcolm Mason, Nicola Cooper, Nur, Ula, Bernard Rachet, Mahesh K.B. Parmar, Parmar, Mahesh K. B., Coleman, Michel P, Sydes, Mathew R, Sydes, Mathew R., Ula Nur, Mason, Malcolm David, Tim Oliver, Rachet, Bernard, Mason, Malcolm, Sally Stenning   +23 more
core   +1 more source

HNF1β is a sensitive and specific novel marker for yolk sac tumor: a tissue microarray analysis of 601 testicular germ cell tumors. [PDF]

, 2020
Hepatocyte Nuclear Factor 1 beta (HNF1β) is a transcription factor which plays an important role during early organogenesis, especially of the pancreato-biliary and urogenital tract.
Christiansen, Ailsa, Gallo, Alessandra, Hermanns, Thomas, Bode, Peter Karl, Moch, Holger, Fankhauser, Christian, Beyer, Jörg   +6 more
core   +1 more source

Transformed Testicular Teratoma to Embryonic-Type Neuroectodermal Tumor With Metastasis to Mediastinum

Journal of Investigative Medicine High Impact Case Reports, 2023
Testicular teratomas may present in both prepubertal and adult men; however, the prognosis differs greatly between these 2 populations. In children, teratomas (prepubertal type) most often occur before the age of 4, are generally seen in their pure form,
Alanna Siegenthaler MD, Stephanie Niforatos MD, Taylor Loon MBBCh, Amy Brady DO, Michael Sandhu MD, Oleksandr Kravtsov MD, Komal Akhtar MD   +6 more
doaj   +1 more source

Germline Exome Sequencing for Men with Testicular Germ Cell Tumor Reveals Coding Defects in Chromosomal Segregation and Protein-targeting Genes. [PDF]

Eur Urol
Pyle LC, Kim J, Bradfield J, Damrauer SM, D'Andrea K, Einhorn LH, Godse R, Hakonarson H, Kanetsky PA, Kember RL, Jacobs LA, Maxwell KN, Rader DJ, Vaughn DJ, Weathers B, Wubbenhorst B, Regeneron Genetics Center Research Team, Cancer Genomics Research Laboratory, Greene MH, Nathanson KL, Stewart DR.   +20 more
europepmc   +2 more sources

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]

, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M., Ana Monteiro, Abel Margaret, Margaret Abel, Peter J. O’Shaughnessy (171628), O’Shaughnessy Peter J., Monteiro, A., O'Shaughnessy, P.J., Ana Monteiro (171632), Peter J O'Shaughnessy, Margaret Abel (171636), Monteiro Ana   +11 more
core   +2 more sources

Testicular seminoma arising from infertile testes 6 years after microdissection testicular sperm extraction

IJU Case Reports, 2022
Introduction In Western countries, the risk of a testicular germ cell tumor in men with male factor infertility is greater than in the general population. However, Japanese data on this risk are lacking.
Nobuhiko Shimizu, Taku Naiki, Daichi Kobayashi, Aya Naiki‐Ito, Tatsuya Kawai, Kuang Xiaochen, Toshiki Etani, Satoshi Nozaki, Nami Tomiyama, Maria Aoki, Nayuka Matsuyama, Shoichiro Iwatsuki, Yukihiro Umemoto, Takahiro Yasui   +13 more
doaj   +1 more source

Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice [PDF]

, 2009
<b>Background</b>: Testicular microliths are calcifications found within the seminiferous tubules. In humans, testicular microlithiasis (TM) has an unknown etiology but may be significantly associated with testicular germ cell tumors ...
Margaret H Abel, Ana Monteiro, Guido Verhoeven, Abel, M.H., Verhoeven, G., De Gendt, K., Monteiro, A., Karl De Gendt, O'Shaughnessy, P.J., Peter J O'Shaughnessy, O'Shaughnessy Peter J, Verhoeven Guido, De Gendt Karl, Abel Margaret H, Monteiro Ana   +14 more
core   +1 more source

Surgical resection in patient with teratoma with somatic‐type malignancy transformed into rhabdomyosarcoma resulted in long‐term survival

IJU Case Reports, 2023
Introduction Testicular germ cell tumors with somatic‐type malignancy, wherein teratomas transform into sarcomas, is drug resistant and has a poor prognosis.
Junji Kitamura, Mitsuhiro Tambo, Ayano Nishijima, Kazuki Masuda, Jimpei Miyakawa, Yu Nakamura, Masachika Fujiwara, Takeshi Kishida, Hiroyuki Ito, Hiroshi Fukuhara   +9 more
doaj   +1 more source