Genomic Diversity of the tet(X)-Positive Myroides Species [PDF]
MicroorganismsThe rapid spread of tet(X) genes capable of inactivating tigecycline represents a critical challenge to global public health. This study aims to explore the distribution, genetic diversity, and transferability of tet(X) genes in Myroides, a genus of Gram-
Chong Chen +3 more
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Rapid and Accurate Antibiotic Susceptibility Determination of tet(X)-Positive E. coli Using RNA Biomarkers [PDF]
Microbiology Spectrum, 2021 The emergence and prevalence of novel plasmid-mediated tigecycline resistance genes, namely, tet(X) and their variants, pose a serious threat to public health worldwide.
Haijie Zhang +7 more
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Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations [PDF]
Frontiers in MicrobiologyIntroductionThe emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical ...
Juan Liu +22 more
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Establishment of Specific Multiplex PCR Detection Methods for the Predominant tet(X)-Positive Acinetobacter Species [PDF]
MicroorganismsThe increasing prevalence of the mobile tigecycline resistance gene tet(X) poses a severe global health threat, and the genus Acinetobacter is a major reservoir.
Chong Chen +4 more
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Epidemiological and phylogenetic analysis reveals Flavobacteriaceae as potential ancestral source of tigecycline resistance gene tet(X) [PDF]
Nature Communications, 2020 Emergence of tigecycline-resistance tet(X) genes is of concern. Here, the authors determine tet(X) prevalence in more than 6,000 clinical Gram-negative bacterial isolates collected between 1994 to 2019 in hospitals in China and suggest that ...
Rong Zhang +14 more
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Various Profiles of tet Genes Addition to tet(X) in Riemerella anatipestifer Isolates From Ducks in China [PDF]
Frontiers in Microbiology, 2018 To investigate tetracycline resistance and resistant genotype in Riemerella anatipestifer, the tetracycline susceptibility of 212 R. anatipestifer isolates from China between 2011 and 2017 was tested.
De-Kang Zhu +23 more
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A method for screening tigecycline-resistant gene tet(X) from human gut
Journal of Global Antimicrobial Resistance, 2021 Objectives: To develop an effective enrichment method for tet(X) detection, we performed PCR and Sanger sequencing to screen and confirm the presence of tet(X) gene. Methods: Species were identified by MALDI-TOF MS analysis.
Yu Zeng +9 more
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Broad-host-range IncW plasmid harbouring tet(X) in Escherichia coli isolated from pigs in Japan
Journal of Global Antimicrobial Resistance, 2022 : Objectives: Tetracyclines are used in veterinary medicine for livestock. Tigecycline, a semisynthetic tetracycline derivative, is a last-resort antimicrobial used to treat multidrug-resistant Gram-negative bacterial infections.
Masaru Usui +4 more
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Rapid Detection of High-Level Tigecycline Resistance in Tet(X)-Producing Escherichia coli and Acinetobacter spp. Based on MALDI-TOF MS [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 The emergence and spread of the novel mobile Tet(X) tetracycline destructases confer high-level tigecycline and eravacycline resistance in Escherichia coli and Acinetobacter spp. and pose serious threats to human and animal health. Therefore, a rapid and
Ze-Hua Cui +32 more
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Concurrence of Inactivation Enzyme-Encoding Genes tet(X), blaEBR, and estT in Empedobacter Species from Chickens and Surrounding Environments [PDF]
FoodsThe emergence of inactivation enzyme-encoding genes tet(X), blaEBR, and estT challenges the effectiveness of tetracyclines, β-lactams, and macrolides.
Chong Chen +5 more
doaj +2 more sources