Results 51 to 60 of about 54,573 (154)

Polymorphism Existence of Mobile Tigecycline Resistance Gene tet (X4) in Escherichia coli [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2020
Recently, two novel plasmid-mediated tigecycline resistance genes, tet (X3) and tet (X4), were identified in Acinetobacter baumannii and Escherichia coli, respectively, both of which can significantly compromise the efficacy of tigecycline ([1][1][–][2][3][3]), which is one of the few ...
Huangwei, Song   +9 more
openaire   +2 more sources

Antimicrobial Resistance and Genomic Epidemiology of tet(X4)-Bearing Bacteria of Pork Origin in Jiangsu, China. [PDF]

open access: yesGenes (Basel), 2022
The emergence of tigecycline-resistant bacteria in agri-food chains poses a public health concern. Recently, plasmid-mediated tet(X4) was found to be resistant to tigecycline. However, genome differences between tet(X4)-positive Escherichia coli of human and pork origins are still under-investigated.
Li Y, Li Y, Bu K, Wang M, Wang Z, Li R.
europepmc   +3 more sources

A multinomial quadrivariate D-vine copula mixed model for meta-analysis of diagnostic studies in the presence of non-evaluable subjects [PDF]

open access: yes, 2020
Diagnostic test accuracy studies observe the result of a gold standard procedure that defines the presence or absence of a disease and the result of a diagnostic test.
Aristidis K Nikoloulopoulos   +4 more
core   +2 more sources

Deciphering the Structural Diversity and Classification of the Mobile Tigecycline Resistance Gene tet(X)-Bearing Plasmidome among Bacteria

open access: yesmSystems, 2020
The emergence of novel plasmid-mediated resistance genes constitutes a great public concern. Recently, mobile tet(X) variants were reported in diverse pathogens from different sources.
Ruichao Li   +7 more
doaj   +1 more source

Histone-Like Nucleoid Structuring Protein Modulates the Fitness of tet(X4)-Bearing IncX1 Plasmids in Gram-Negative Bacteria

open access: yesFrontiers in Microbiology, 2021
The emergence of plasmid-mediated tigecycline resistance gene tet(X4) poses a challenging threat to public health. Based on the analysis of tet(X4)-positive plasmids in the NCBI database, we found that the IncX1-type plasmid is one of the most common ...
Wenhui Cai   +13 more
doaj   +1 more source

Distribution and genomic characterization of tigecycline-resistant tet(X4)-positive Escherichia coli of swine farm origin. [PDF]

open access: yesMicrob Genom, 2021
Abstract The emergence of plasmid-mediated tigecycline-resistant strains is posing a serious threat to food safety and human health, which has attracted worldwide attention. The tigecycline resistance gene tet(X4) has been found in diverse sources, but the distribution of tet(X4) and its genetic ...
Li Y   +7 more
europepmc   +3 more sources

Three-Dimensional Manifolds, Skew-Gorenstein Rings and their Cohomology [PDF]

open access: yes, 2010
Graded skew-commutative rings occur often in practice. Here are two examples: 1) The cohomology ring of a compact three-dimensional manifold. 2) The cohomology ring of the complement of a hyperplane arrangement (the Orlik-Solomon algebra).
Dedicated To Ralf Fröberg   +1 more
core   +2 more sources

Emergence of plasmid-mediated tigecycline resistance gene, tet(X4), in Escherichia fergusonii from pigs

open access: yesJournal of Global Antimicrobial Resistance, 2022
This study aimed to identify tigecycline-resistant tet(X4)-bearing Escherichia fergusonii isolated from pigs in China with a complete genome sequence.E. fergusonii was isolated by selective medium and screened from tigecycline-supplemented agar plates.
Chunjiu Guan   +5 more
openaire   +3 more sources

Mobilization of tet(X4) by IS1 Family Elements in Porcine Escherichia coli Isolates. [PDF]

open access: yesAntimicrob Agents Chemother, 2022
The dissemination mechanism of the high-level tigecycline resistance gene tet (X4) in porcine Escherichia coli was investigated. tet (X4) and other antimicrobial resistance genes were located on the plasmids p1919D3-1 and p1919D62-1 and flanked by two or three copies ...
Yu R, Chen Z, Schwarz S, Yao H, Du XD.
europepmc   +3 more sources

Advances in mechanism study on novel tetracycline-inactivating enzymes tet(X) causing emerging tigecycline resistance [PDF]

open access: yesZhenduanxue lilun yu shijian, 2023
Antibiotic resistance in bacteria has become a great threat to global public health. Tigecycline is a next-generation tetracycline that is the final line of defense against severe infections by carbapenem-resistant Gram-negative bacteria.
SHEN Pinghua, CHEN Huifen
doaj   +1 more source

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