Results 41 to 50 of about 158 (87)

Vortex‐Induced Vibration Mitigation and Design Optimization of a Long‐Span Bridge Using Multiple Nonlinear Energy Sink Inerters

Structural Control and Health Monitoring, Volume 2026, Issue 1, 2026.
Vortex‐induced vibration (VIV) in long‐span bridges is a typical form of low‐frequency vibration, which is often challenging to address with tuned mass dampers (TMDs) due to their excessive static displacement and poor robustness. Fortunately, this low‐frequency vibration of bridges can be addressed by the nonlinear energy sink inerter (NESI), owing to
Ruihong Xie, Oya Mercan, Kun Xu, Lin Zhao, Jian Zhang   +4 more
wiley   +1 more source

The ISVsa3-ORF2-abh-tet(X4) circular intermediate-mediated transmission of tigecycline resistance in Escherichia coli isolates from duck farms

Frontiers in Cellular and Infection Microbiology
Tigecycline is a last-resort drug used to treat serious infections caused by multidrug-resistant bacteria. tet(X4) is a recently discovered plasmid-mediated tigecycline resistance gene that confers high-level resistance to tigecycline and other ...
Chao Jiang, Chao Jiang, Jie Yang, Jie Yang, Gang Xiao, Gang Xiao, Ning Xiao, Ning Xiao, Jie Hu, Yi Yang, Zhiliang Sun, Zhiliang Sun, Yujuan Li, Yujuan Li, Yujuan Li   +14 more
doaj   +1 more source

Whole‐Genome Insights Into Tigecycline‐Resistant Klebsiella Spp. Harboring Colistin Resistance Gene From Food Animals in Türkiye

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Antimicrobial‐resistant (AMR) Klebsiella spp., the common agents of nosocomial infections, are on the rise and becoming increasingly dangerous, with tigecycline‐resistant strains posing a serious clinical threat. This study aimed to characterize isolated tigecycline‐resistant strains from Türkiye by using whole‐genome sequencing (WGS).
Cemil Kürekci, Xiaoyu Lu, Seyda Şahin, Yeşim Soyer, Zhiqiang Wang, Jens A. Hammerl, Ruichao Li, Anusak Kerdsin   +7 more
wiley   +1 more source

Emergence of plasmid-mediated tigecycline resistance tet(X4) gene in Enterobacterales isolated from wild animals in captivity

Science in One Health
Background: Over the past few decades, antimicrobial resistance (AMR) has emerged as a global health challenge in human and veterinary medicine. Research on AMR genes in captive wild animals has increased.
Lei Lei, Panfeng Xiong, Zelin Yan, Yanyan Zhang, Yuchen Wu, Gongxiang Chen, Houhui Song, Rong Zhang   +7 more
doaj   +1 more source

CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang, Qianqian Wang, Jiaming Zhang, Bingyu Li, Yuke Li, Zhengbo Chen, Dandan Guo, Shuying Feng   +7 more
wiley   +1 more source

Unveiling the Genetic Diversity and Antimicrobial Resistance Profiles of Salmonella Population From 2016 to 2020 in Thai Canal Water

Environmental Microbiology Reports, Volume 17, Issue 4, August 2025.
By employing whole genome sequencing to analyse 351 Salmonella genomes isolated between 2016 and 2020, the characteristics and antimicrobial resistance properties of Salmonella enterica found in Bangkok canals were elucidated. Among studied isolates, 39.0% were potentially multidrug‐resistant, and STs 34 and 213 found might have circulated between ...
Jirachaya Toyting‐Hiraishi, Toyotaka Sato, Neunghatai Supha, Yuwanda Thongpanich, Motohiro Horiuchi, Jeewan Thapa, Chie Nakajima, Yasuhiko Suzuki, Fuangfa Utrarachkij   +8 more
wiley   +1 more source

Distribution and spread of tigecycline resistance gene tet(X4) in Escherichia coli from different sources

Frontiers in Cellular and Infection Microbiology
Tigecycline serves as a last-resort antimicrobial agent against severe infections caused by multidrug-resistant bacteria. Tet(X) and its numerous variants encoding flavin-dependent monooxygenase can confer resistance to tigecycline, with tet(X4) being ...
Xin-Yan Fan, Xin-Yan Fan, Yue Jiang, Yue Jiang, Han Wu, Han Wu, Jie Liu, Jie Liu, Qing-Yun Gu, Qing-Yun Gu, Zhen-Yu Wang, Zhen-Yu Wang, Lin Sun, Lin Sun, Xinan Jiao, Xinan Jiao, Qiuchun Li, Qiuchun Li, Jing Wang, Jing Wang   +19 more
doaj   +1 more source

Sensitive and rapid detection of tet(X2) ~ tet(X5) by loop-mediated isothermal amplification based on visual OTG dye

BMC Microbiology, 2023
The emergence of tigecycline-resistant tet(X2/X3/X4/X5) genes poses a new threat to the efficacy of anti-infective therapy and the safety of our food and environment.
Guiling Chen, Lulin Chen, Sisi Lin, Congzhu Yang, Huanlin Liang, Kuang Huang, Zhusheng Guo, Fei Lv   +7 more
doaj   +1 more source

Investigation on Klebsiella pneumoniae in the field of extracellular vesicles

Interdisciplinary Medicine, Volume 3, Issue 4, July 2025.
The role of extracellular vesicles in the pathogenicity and antibiotic resistance, as well as treatment and prevention of Klebsiella pneumoniae. Abstract Klebsiella pneumoniae (KP), recognized for its pronounced antibiotic resistance, is a prevalent agent of nosocomial infections such as hospital‐acquired pneumonia.
Junwei Wu, Yuheng Liu, Jin Su, Yi Yang, Haiyi Deng, Yilin Yang, Mengxi Yanglan, Xinyi Wu, Shiqi Luo, Yao Liao, Lifu Wang   +10 more
wiley   +1 more source

Deciphering comprehensive profiles of pathogenies and resistome of pork using integrating metagenomic and isolation strategies

iMetaOmics, Volume 2, Issue 2, June 2025.
The pork microbiome was investigated using an integrated approach combining isolation and metagenomic sequencing methods to comprehensively analyze the pathogens and resistome on pork surfaces. The study revealed a large number and diversity of pathogens and resistance genes, potentially originating from air, transportation, water, or cross ...
Lianwei Ye, Qiao Hu, Tao Zang, Yaling Wang, Heng Heng, Edward Wai Chi Chan, Sheng Chen   +6 more
wiley   +1 more source