Results 1 to 10 of about 328,500 (323)
Amylase release from streptolysin O-permeabilized pancreatic acinar cells. Effects of Ca2+, guanosine 5'-[gamma-thio]triphosphate, cyclic AMP, tetanus toxin and botulinum A toxin [PDF]
The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O.
Ahnert-Hilger, G.+4 more
core
Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila [PDF]
Glued1 (Gl1) mutants produce a truncated protein that acts as a poison subunit and disables the cytoplasmic retrograde motor dynein. Heterozygous mutants have axonal defects in the adult eye and the nervous system.
Allen, Marcus James+5 more
core +1 more source
The hydrophobicities of cholera toxin, tetanus toxin and their components [PDF]
1. Charge-shift electrophoresis showed that cholera toxin and its subunits have no hydrophobic surfaces. 2. Amino-acid composition and sequence data suggested that the proteins have no masked hydrophobic regions. 3. The A subunit of cholera toxin may interact with polar molecules in the membrane to exert its effect inside the cell. 4.
S van Heyningen, P Britton, Wally Ward
openaire +3 more sources
Bacterial Toxins, Current Perspectives
Toxins are the major pathogenicity factors produced by numerous bacteria involved in severe diseases in humans and animals. Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease.
Michel R. Popoff
doaj +1 more source
Studies on Tetanus Toxin and Toxid. II. Isolation and Characterization of the Tetanus Toxin and Toxoid [PDF]
Crude tetanus toxin and toxoid were prepared by methanol precipitation. The toxin was purified by a combination of TEAE cellulose and Sephadex G 200 chromatography at pH values less than 6 o. The toxoid was purified by DEAE cellulose at approximately neutral pH values.
CM Mauritzen, DJ Dawson
openaire +3 more sources
A genetic fusion GDNF-C fragment of tetanus toxin prolongs survival in a symptomatic mouse ALS model
Purpose: Amyotrophic Lateral Sclerosis (ALS) is a paralyzing disorder that kills individuals within three to five years of onset without any possibility for effective treatment. One proposed therapy has been the use of neurotrophic factors to inhibit the
Jesús Ciriza+9 more
semanticscholar +1 more source
Development of IgY antibodies for control of tetanus [PDF]
Tetanus is a cut and often highly fatal infectious disease that affects both human and animals; the disease caused by exotoxin which produced by C. tetani.
Selim A.M.+3 more
doaj
More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines
Clostridium tetani is the etiological agent of tetanus, a life-threatening bacterial infection. The most efficient protection strategy against tetanus is a vaccination with the C.
Jens Möller+2 more
doaj +1 more source
Bead-based assay systems offer the possibility of measuring several specific antibodies in one sample simultaneously. This study evaluated a vaccine panel of a multianalyte system that measures antibodies to tetanus toxin, diphtheria toxin, and pertussis
S. Reder+3 more
semanticscholar +1 more source
A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe+8 more
doaj