Results 31 to 40 of about 15,945 (179)
A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe +8 more
doaj
Development of IgY antibodies for control of tetanus [PDF]
Tetanus is a cut and often highly fatal infectious disease that affects both human and animals; the disease caused by exotoxin which produced by C. tetani.
Selim A.M. +3 more
doaj
Conflicting adaptations in an inhibitory feedback circuit
Abstract figure legend We studied activity‐dependent adaptation in the fruit fly Drosophila’s memory centre, the mushroom body. Here, excitatory Kenyon cells (KCs) receive feedback inhibition from the anterior paired lateral (APL) neuron. When KCs are artificially overactivated for 24 h, both KCs and APL reduce their sensitivity to excitation (‘↓ Exc’,
Gregor A. Bergmann +5 more
wiley +1 more source
Tetanus is a disease that occurs in humans and various animal species worldwide. Tetanus toxin, after binding itself to nerve structures in the spinal cord, blocking the release of inhibitory transmitors which results in predominance of excitatory ...
Indira Mujezinović +2 more
doaj
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot +3 more
wiley +1 more source
More than a Toxin: Protein Inventory of Clostridium tetani Toxoid Vaccines
Clostridium tetani is the etiological agent of tetanus, a life-threatening bacterial infection. The most efficient protection strategy against tetanus is a vaccination with the C.
Jens Möller +2 more
doaj +1 more source
Structural basis of tetanus toxin neutralization by native human monoclonal antibodies
Summary: Four potent native human monoclonal antibodies (mAbs) targeting distinct epitopes on tetanus toxin (TeNT) are isolated with neutralization potency ranging from approximately 17 mg to 6 mg each that are equivalent to 250 IU of human anti-TeNT ...
Yueming Wang +18 more
doaj +1 more source
ABSTRACT Recombinant protein expression in heterologous biological systems is an expanding field in synthetic biology. Photosynthetic organisms have the potential to provide an efficient low‐cost platform for recombinant protein production because they require minimal growth nutrients and are less susceptible to zoonotic and other contaminants ...
Bharat Kumar Majhi, Anastasios Melis
wiley +1 more source
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh +11 more
wiley +1 more source
Bacterial Toxins, Current Perspectives
Toxins are the major pathogenicity factors produced by numerous bacteria involved in severe diseases in humans and animals. Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease.
Michel R. Popoff
doaj +1 more source

