Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]
, 1994 Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G. +28 more
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Infection in a Geriatric Patient: Do Not Let Your Guard Off! [PDF]
Annals of Geriatric Medicine and Research, 2023 Tetanus is an infectious disease caused by Clostridium tetani toxin. Although easily preventable through vaccination, over 73,000 new infections and 35,000 deaths due to tetanus occurred worldwide in 2019, with higher rates in countries with healthcare ...
Alessandra Piscitelli +9 more
doaj +1 more source
Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy [PDF]
, 2010 High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone.
Cmejla, Roman +5 more
core +3 more sources
Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin
Pharmaceuticals, 2021 Tetanus neurotoxin (TeNT) is a protein exotoxin produced by Clostridium tetani that causes the deadly spastic neuroparalysis of tetanus. It consists of a metalloprotease light chain and of a heavy chain linked via a disulphide bond.
Giulia Zanetti +5 more
doaj +1 more source
Studies on Tetanus Toxin and Toxoid IV. Interaction of Formaldehyde with Tetanus Toxin [PDF]
Australian Journal of Biological Sciences, 1969 The binding of formaldehyde with tetanus toxin under mild detoxificatIOn conditions (0 ·1M phosphate buffer, pH 7· 0, O· 005-0· 06M HCHO, 20-37°C) has been studied quantitatively by using [14C]formaldehyde. When detoxification was followed with time (0· 005M HCHO, 37°C) the toxin showed a characteristic immediate drop in lethality (~80%), followed by a
D J, Dawson, C M, Mauritzen
openaire +2 more sources
Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion [PDF]
, 1989 Conditions are described for controlled plasma membrane permeabilization of rat pheochromocytoma cells (PC12) and cultured bovine adrenal chromaffin cells by Streptolysin O (SLO).
Ahnert-Hilger G. +29 more
core +1 more source
International Journal of Emergency Medicine, 2021 Background Tetanus is a rare disease caused by Clostridium tetani, which produces tetanolysin and tetanospasmin. In 2018, there were only approximately ten tetanus cases reported in Indonesia.
Dzulfikar D. L. Hakim +6 more
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From Bacterial Poisons to Toxins: The Early Works of Pasteurians
Toxins, 2022 We review some of the precursor works of the Pasteurians in the field of bacterial toxins. The word “toxin” was coined in 1888 by Ludwig Brieger to qualify different types of poison released by bacteria.
Jean-Marc Cavaillon
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Millimolar concentrations of free magnesium enhance exocytosis from permeabilized rat pheochromocytoma (PC 12) cells [PDF]
, 1989 The role of Mg2+ during the final steps of exocytosis was investigated using rat pheochromocytoma cells (PC12) permeabilized with bacterial pore forming toxins.
Ahnert-Hilger +17 more
core +1 more source
Эпидемиология и вакцинопрофилактика, 2022 Relevance. Diphtheria toxoid (DT) and tetanus toxoid (TT) manufacturing appears as many steps process. On every stage of proceeding vaccine the control of critical points is being provided.
E. I. Komarovskaya, O. V. Perelygyna
doaj +1 more source