Results 11 to 20 of about 48,054 (298)

Time Trends of Tetrahydrocannabinol (THC) in a 2008–2021 German National Survey of Hemp Food Products

Foods, 2022
∆9-Tetrahydrocannabinol (THC) is known as the main psychotropic compound present in the hemp plant. It also occurs in commercially available hemp food products and may have adverse effects on consumers.
Hannah Dräger, Ines Barthlott, Patricia Golombek, Stephan G. Walch, Dirk W. Lachenmeier   +4 more
doaj   +1 more source

In the Swim of Cannabis: Developmental Toxicity and Metabolomic Pathway Alterations of Zebrafish Larvae Exposed to THC for the Assessment of Its Potential Environmental and Human Health Impact

Molecules, 2022
As the pharmacological properties and therapeutic applications of Cannabis sativa L. pace with the upsurge of interest of the scientific community in harnessing its constituent phytocannabinoids, illicit use may raise serious health issues ...
Theodoros Chatzimitakos, Ieremias Chousidis, Dimitrios Leonardos, Constantine Stalikas, Ioannis Leonardos   +4 more
doaj   +1 more source

Drug Use on Mont Blanc: A Study Using Automated Urine Collection [PDF]

, 2016
Mont Blanc, the summit of Western Europe, is a popular but demanding high-altitude ascent. Drug use is thought to be widespread among climbers attempting this summit, not only to prevent altitude illnesses, but also to boost physical and/or psychological
Botre', Francesco, Bouzat, Pierre, Buisson, Corinne, de la Torre, Xavier, Kérivel, Patricia, Lasne, Françoise, Mazzarino, Monica, Méchin, Nathalie, Robach, Paul, Roustit, Matthieu, Trebes, Gilles   +10 more
core   +12 more sources

Sex Differences in Tolerance to Delta-9-Tetrahydrocannabinol in Mice With Cisplatin-Evoked Chronic Neuropathic Pain

Frontiers in Molecular Biosciences, 2021
Tolerance to the pain-relieving effects of cannabinoids limits the therapeutic potential of these drugs in patients with chronic pain. Recent preclinical research with rodents and clinical studies in humans has suggested important differences between ...
Angela N. Henderson-Redmond, Angela N. Henderson-Redmond, Angela N. Henderson-Redmond, LaTaijah C. Crawford, LaTaijah C. Crawford, Diana E. Sepulveda, Diana E. Sepulveda, David E. Hale, Julia J. Lesperance, Daniel J. Morgan, Daniel J. Morgan, Daniel J. Morgan, Daniel J. Morgan   +12 more
doaj   +1 more source

Delta‐9‐tetrahydrocannabinol disrupts mitochondrial function and attenuates syncytialization in human placental BeWo cells

Physiological Reports, 2020
The psychoactive component in cannabis, delta‐9‐tetrahydrocannabinol, can restrict fetal growth and development. Delta‐9‐tetrahydrocannabinol has been shown to negatively impact cellular proliferation and target organelles like the mitochondria resulting
O’Llenecia S. Walker, Rehginald Ragos, Harmeet Gurm, Mariah Lapierre, Linda L. May, Sandeep Raha   +5 more
doaj   +1 more source

Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Emotion, Cognition, and Attention: A Double-Blind, Placebo-Controlled, Randomized Experimental Trial in Healthy Volunteers

Frontiers in Psychiatry, 2020
The two main phytocannabinoids—delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)—have been extensively studied, and it has been shown that THC can induce transient psychosis. At the same time, CBD appears to have no psychotomimetic potential.
Timo Woelfl, Cathrin Rohleder, Cathrin Rohleder, Juliane K. Mueller, Juliane K. Mueller, Bettina Lange, Anne Reuter, Anna Maria Schmidt, Dagmar Koethe, Dagmar Koethe, Martin Hellmich, F. Markus Leweke, F. Markus Leweke   +12 more
doaj   +1 more source

Cannabinoids in the treatment of epilepsy: current status and future prospects [PDF]

, 2020
Cannabidiol (CBD) is one of the prominent phytocannabinoids found in Cannabis sativa, differentiating from Δ9-tetrahydrocannabinol (THC) for its non-intoxicating profile and its antianxiety/antipsychotic effects.
Albini M., Cifelli P., Di Bonaventura C., Fanella M., Giallonardo A. T., Morano A., Palma E.   +6 more
core   +1 more source

Self-administration of edible Δ9-tetrahydrocannabinol and associated behavioral effects in mice [PDF]

, 2019
Background With increasing access to legal cannabis across the globe, it is imperative to more closely study its behavioral and physiological effects.
Boehm, Stephen L., II, Lapish, Christopher C., Mackie, Ken, Smoker, Michael P.   +3 more
core   +2 more sources

Enzymatic digestion and selective quantification of underivatised [delta]9-tetrahydrocannabinol and cocaine in human hair using gas chromatography-mass spectrometry. [PDF]

, 2012
Gas chromatography-mass spectrometric (GC-MS) methods for drug analysis routinely employ derivatising reagents. The aim of this paper was to develop a method for the analysis of two recreational drugs, delta-9-tetrahydrocannabinol ([delta](9)-THC) and ...
Barker, James, Breidi, Salah Eddine, Naughton, Declan, Petroczi, Andrea   +3 more
core   +3 more sources

EVALI Vaping Liquids Part 1: GC-MS Cannabinoids Profiles and Identification of Unnatural THC Isomers

Frontiers in Chemistry, 2021
Tetrahydrocannabinol (THC)-containing products played a major role in the 2019 US nationwide outbreak of pulmonary lung illness associated with e-cigarettes or vaping liquids (EVALI).
Laura A. Ciolino, Tracy L. Ranieri, Jana L. Brueggemeyer, Allison M. Taylor, Angela S. Mohrhaus   +4 more
doaj   +1 more source