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Tetrahydrocannabivarin is Not Tetrahydrocannabinol

Cannabis & Cannabinoid Research
Tetrahydrocannabivarin (THCV) is a phytocannabinoid that is becoming popular across the North American cannabis market. THCV has been reported to reduce blood sugar and act as an appetite suppressant in several independent pre-clinical studies, which has earned it the popular nickname of “diet weed,” despite few human studies of these effects ...
Mehdi Haghdoost, Erica N. Peters, Matthew Roberts, Marcel O. Bonn-Miller   +3 more
openaire   +2 more sources

Tetrahydrocannabinols

Cancer and Metastasis Reviews, 2023
Tetrahydrocannabinols (THCs) antagonize the CB1 and CB2 cannabinoid receptors, whose signaling to the endocannabinoid system is essential for controlling cell survival and proliferation as well as psychoactive effects. Most tumor cells express a much higher level of CB1 and CB2; THCs have been investigated as potential cancer therapeutic due to their ...
Prateeksha, Prateeksha, Sharma, Vivek K., Singh, Shiv M., Sharma, Minaxi, Diwan, Deepti, Hesham, Abd El Latif, Guleria, Sanjay, Nguyen, Quang D., Gupta, Vijai K., Singh, Brahma N.   +9 more
openaire   +1 more source

Cannabidiol and tetrahydrocannabinol concentrations in commercially available CBD E-liquids in Switzerland. [PDF]

, 2020
Cannabidiol (CBD) rich hemp and hemp products low in Δ9-tetrahydrocannabinol (THC) (less than 1%) are legally available in Switzerland. Besides herbs for smoking and oils, liquids (e-liquids) for smoking in electronic cigarettes (e-cigs) have recently ...
Weinmann, Wolfgang, Grafinger, Katharina Elisabeth, Broillet, Alain, Krönert, Severine   +3 more
core   +3 more sources

Effect of maternal Δ9-tetrahydrocannabinol on developing serotonergic system

, 1996
In this study we investigated the effects of maternal hg-tetrahydrocannabinol on the developing serotonergic system. A daily dose of Delta(9)-tetrahydrocannabinol (5 mg/kg body weight) was administered p.o.
Maria L. Leret, Alberto Amaro, Leret, ML, Francisco Molina-Holgado, Gonzalez, MI, M.Isabel González, Amaro, A, Francisco J. Alvarez, Molina-Holgado, Francisco, Alvarez, FJ   +9 more
core   +2 more sources

Assessment of clinical outcomes in patients with fibromyalgia: Analysis from the UK Medical Cannabis Registry

Brain and Behavior, 2023
Introduction : There are limited therapeutic options for individuals with fibromyalgia. The aim of this study is to analyze changes in health‐related quality of life and incidence of adverse events of those prescribed cannabis‐based medicinal products ...
Claire Wang, Simon Erridge, Carl Holvey, Ross Coomber, Azfer Usmani, Mohammed Sajad, Rahul Guru, Wendy Holden, James J. Rucker, Michael W. Platt, Mikael H. Sodergren   +10 more
doaj   +1 more source

Pharmacokinetics of Cannabidiol Following Intranasal, Intrarectal, and Oral Administration in Healthy Dogs

Frontiers in Veterinary Science, 2022
The therapeutic potential of cannabidiol (CBD), a non-psychtropic component of the Cannabis sativa plant, is substantiated more and more. We aimed to determine the pharmacokinetic behavior of CBD after a single dose via intranasal (IN) and intrarectal ...
Dakir Polidoro, Robin Temmerman, Mathias Devreese, Marios Charalambous, Marios Charalambous, Luc Van Ham, Ine Cornelis, Bart J. G. Broeckx, Paul J. J. Mandigers, Andrea Fischer, Jan Storch, Sofie F. M. Bhatti   +11 more
doaj   +1 more source

Plasma protein binding of 7-hydroxy-Δ1-tetrahydrocannabinol: an active Δ1-tetrahydrocannabinol metabolite

, 1973
7-Hydroxy-Δ1-tetrahydrocannabinol, which is a pharmacologically and psychologically active metabolite of Δ1-tetrahydrocannabinol in man, has been shown by equilibrium dialysis and ultrafiltration to be bound 94–99% to plasma proteins. Further experiments,
B Granstrand, M Widman, H Borg, S Agurell, I M Nilsson, J L G Nilsson   +5 more
core   +1 more source

Topical and Systemic Cannabidiol Improves Trinitrobenzene Sulfonic Acid Colitis in Mice [PDF]

, 2012
Background/Aims: Compounds of Cannabis sativa are known to exert anti-inflammatory properties, some of them without inducing psychotropic side effects. Cannabidiol (CBD) is such a side effect-free phytocannabinoid that improves chemically induced colitis
Martin Storr, Storr, Martin, Rudolf Schicho, Schicho, Rudolf   +3 more
core   +1 more source

Delta-9-tetrahydrocannabinol (THC) Measurement Uncertainty Dataset [PDF]

, 2020
Method validation data generated as part of quantifying the measurement uncertainty of delta-9-tetrahydrocannabinol (THC, the main active ingredient of cannabis) in whole Blood using SPE and LC/MS/MS Key words calibration curve, coverage factor, method ...
Klu, Joyce; id_orcid, Leverhulme Research Centre for Forensic Science, Officer, Jane A., Nic Daeid, Niamh; id_orcid, Mudie, Roy, Scottish Police Authority, Park, Alexandra   +6 more
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In planta Female Flower Agroinfiltration Alters the Cannabinoid Composition in Industrial Hemp (Cannabis sativa L.)

Frontiers in Plant Science, 2022
Industrial hemp is a diploid (2n = 20), dioecious plant, and an essential source of various phytochemical productions. More than 540 phytochemicals have been described, some of which proved helpful in the remedial treatment of human diseases.
Michihito Deguchi, Seema Dhir, Shobha Potlakayala, Sarwan Dhir, Wayne R. Curtis, Sairam Rudrabhatla   +5 more
doaj   +1 more source