Results 61 to 70 of about 20,460 (225)

Cannabis and Autoimmunity: Possible Mechanisms of Action

open access: yesImmunoTargets and Therapy, 2021
Valeria Giorgi1 1, Daniela Marotto2 2, Alberto Batticciotto3 3, Fabiola Atzeni4 4, Sara Bongiovanni1 1, Piercarlo Sarzi-Puttini1 1 1Rheumatology Unit, Internal Medicine Department, ASST Fatebenefratelli-Sacco, Milan University School of Medicine, Milan ...
Giorgi V   +5 more
doaj  

Tetrahydrocannabinol (THC) cartridge ingestion

open access: yesJournal of Pediatric Surgery Case Reports, 2020
We present the case of a 16-year-old male who ingested the tetrahydrocannabinol (THC) oil filled cartridge of a vape pen. With the recent increasing incidence of vaping related illnesses there is a significant focus on the hazards of the increasing use ...
Logan Meyer, Sathyaprasad Burjonrappa
doaj   +1 more source

Influence of Different Washing Hair Procedures in the Quantitative Determination of THC and THCCOOH

open access: yesDrug Testing and Analysis, EarlyView.
Different hair decontamination protocols significantly affect THC quantification, with marked analyte loss—particularly after aqueous‐organic washing—whereas THCCOOH remains stable. These findings highlight the risk of misinterpretation and the need for standardized washing procedures in hair analysis.
Valentina Martini   +8 more
wiley   +1 more source

Tetrahydrocannabinol and dopamine D1 receptor

open access: yesFrontiers in Neuroscience, 2023
Dopamine, a neurotransmitter and neuromodulator, is primarily released by dopaminergic neurons in the midbrain, particularly in the substantia nigra and the ventral tegmental area (VTA). Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family.
openaire   +3 more sources

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

open access: yesDrug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão   +4 more
wiley   +1 more source

The impact of recreational cannabinoid legalization on utilization in a pregnant population

open access: yesFrontiers in Public Health
BackgroundMarijuana potency and utilization both continue to increase across the United States. While the overall prevalence of cannabinoid utilization during pregnancy has been surveyed in various studies, the direct impact of changing governmental ...
Jacob Torres   +5 more
doaj   +1 more source

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota   +8 more
wiley   +1 more source

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud   +2 more
wiley   +1 more source

Documented End‐of‐Life Preferences of People With Parkinson's Disease or Parkinsonism Across Europe

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease and atypical parkinsonism are characterized by motor and non‐motor symptoms. As the disease advances, planning for end‐of‐life (EoL) care becomes increasingly important. However, consensus‐based European guidelines for advance care planning and documentation of EoL care preferences for parkinsonism are lacking ...
Bauke W. Dijkstra   +30 more
wiley   +1 more source

Gray Matter Volume Loss in Parkinson's Disease Psychosis and Cannabinoid Receptor Gene Expression in the Brain

open access: yesMovement Disorders, EarlyView.
Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani   +3 more
wiley   +1 more source

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