Results 21 to 30 of about 30,694 (295)

The overview of existing knowledge on medical cannabis plants growing

Plant, Soil and Environment, 2021
The use of cannabis for medicinal purposes dates back well before the era of modern medicine, but in recent years research into the use of medical cannabis in the medical and pharmaceutical sciences has grown significantly.
Matěj Malík, Jiří Velechovský, Pavel Tlustoš   +2 more
doaj   +1 more source

Self-report methodology for quantifying standardized cannabis consumption in milligrams delta-9-tetrahydrocannabinol

, 2023
Background: There is currently no format-independent method to determine delta-9-tetrahydrocannabinol (THC) in milligrams for self-report studies.
Mary E. Larimer (10299772), Natalia M. Kleinhans (10888050), Stephen R. Dager (9962930), Sarah F. Larsen (16706390), Allegra J. Johnson (16706393)   +4 more
core   +1 more source

Manipulation of THC Hair Concentrations by Commercially Available Products

Metabolites, 2022
Many drug tests are carried out by means of hair analysis. The aim of the present study was to clarify if and to what extent it is possible to manipulate the results of hair analyses on tetrahydrocannabinol (THC) by using various commercially available ...
Markus Bertges, Alexandra Ketikidou, Ralf Weiskirchen, Josef van Helden, Rudolf Boehnke, Cornelius Hess   +5 more
doaj   +1 more source

Combinations of Cannabidiol and Δ⁹-Tetrahydrocannabinol in Reducing Chemotherapeutic Induced Neuropathic Pain

Biomedicines, 2022
Neuropathic pain is a condition that impacts a substantial portion of the population and is expected to affect a larger percentage in the future. This type of pain is poorly managed by current therapies, including opioids and NSAIDS, and novel approaches
Diana E. Sepulveda, Kent E. Vrana, Nicholas M. Graziane, Wesley M. Raup-Konsavage   +3 more
doaj   +1 more source

Delta‐9‐tetrahydrocannabinol disrupts mitochondrial function and attenuates syncytialization in human placental BeWo cells

Physiological Reports, 2020
The psychoactive component in cannabis, delta‐9‐tetrahydrocannabinol, can restrict fetal growth and development. Delta‐9‐tetrahydrocannabinol has been shown to negatively impact cellular proliferation and target organelles like the mitochondria resulting
O’Llenecia S. Walker, Rehginald Ragos, Harmeet Gurm, Mariah Lapierre, Linda L. May, Sandeep Raha   +5 more
doaj   +1 more source

Time Trends of Tetrahydrocannabinol (THC) in a 2008–2021 German National Survey of Hemp Food Products

Foods, 2022
∆9-Tetrahydrocannabinol (THC) is known as the main psychotropic compound present in the hemp plant. It also occurs in commercially available hemp food products and may have adverse effects on consumers.
Hannah Dräger, Ines Barthlott, Patricia Golombek, Stephan G. Walch, Dirk W. Lachenmeier   +4 more
doaj   +1 more source

Continuous-Flow Synthesis of Δ⁹‑Tetrahydrocannabinol and Δ⁸‑Tetrahydrocannabinol from Cannabidiol

, 2023
A challenging step in the preparation of tetrahydrocannabinol analogs is an acid-catalyzed intramolecular cyclization of the cannabidiol precursor. This step typically affords a mixture of products, which requires extensive purification to obtain any ...
Christopher A. Hone (4090777), C. Oliver Kappe (1264179), Benedetta Bassetti, C. Oliver Kappe, Benedetta Bassetti (15181477), Christopher A. Hone   +5 more
core   +1 more source

In the Swim of Cannabis: Developmental Toxicity and Metabolomic Pathway Alterations of Zebrafish Larvae Exposed to THC for the Assessment of Its Potential Environmental and Human Health Impact

Molecules, 2022
As the pharmacological properties and therapeutic applications of Cannabis sativa L. pace with the upsurge of interest of the scientific community in harnessing its constituent phytocannabinoids, illicit use may raise serious health issues ...
Theodoros Chatzimitakos, Ieremias Chousidis, Dimitrios Leonardos, Constantine Stalikas, Ioannis Leonardos   +4 more
doaj   +1 more source

Sex Differences in Tolerance to Delta-9-Tetrahydrocannabinol in Mice With Cisplatin-Evoked Chronic Neuropathic Pain

Frontiers in Molecular Biosciences, 2021
Tolerance to the pain-relieving effects of cannabinoids limits the therapeutic potential of these drugs in patients with chronic pain. Recent preclinical research with rodents and clinical studies in humans has suggested important differences between ...
Angela N. Henderson-Redmond, Angela N. Henderson-Redmond, Angela N. Henderson-Redmond, LaTaijah C. Crawford, LaTaijah C. Crawford, Diana E. Sepulveda, Diana E. Sepulveda, David E. Hale, Julia J. Lesperance, Daniel J. Morgan, Daniel J. Morgan, Daniel J. Morgan, Daniel J. Morgan   +12 more
doaj   +1 more source

Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Emotion, Cognition, and Attention: A Double-Blind, Placebo-Controlled, Randomized Experimental Trial in Healthy Volunteers

Frontiers in Psychiatry, 2020
The two main phytocannabinoids—delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)—have been extensively studied, and it has been shown that THC can induce transient psychosis. At the same time, CBD appears to have no psychotomimetic potential.
Timo Woelfl, Cathrin Rohleder, Cathrin Rohleder, Juliane K. Mueller, Juliane K. Mueller, Bettina Lange, Anne Reuter, Anna Maria Schmidt, Dagmar Koethe, Dagmar Koethe, Martin Hellmich, F. Markus Leweke, F. Markus Leweke   +12 more
doaj   +1 more source