Results 11 to 20 of about 30,694 (295)

Quantification and prediction of human fetal (-)-Δ9-tetrahydrocannabinol/(±)-11-OH-Δ9-tetrahydrocannabinol exposure during pregnancy to inform fetal cannabis toxicity

Nature Communications
Prenatal cannabis use is associated with neurodevelopmental deficits, likely due to exposure to the psychoactive cannabinoid, (-)-Δ9-tetrahydrocannabinol, and its active metabolite, (±)-11-OH-Δ9-tetrahydrocannabinol.
Aditya R. Kumar, Lyndsey S. Benson, Erica M. Wymore, Jocelyn E. Phipers, Jennifer C. Dempsey, Lucinda A. Cort, Jashvant D. Unadkat   +6 more
doaj   +2 more sources

Tetrahydrocannabinol and dopamine D1 receptor [PDF]

Frontiers in Neuroscience, 2023
Dopamine, a neurotransmitter and neuromodulator, is primarily released by dopaminergic neurons in the midbrain, particularly in the substantia nigra and the ventral tegmental area (VTA). Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family.
Jiwon, Lee
openaire   +4 more sources

Delta-8 Tetrahydrocannabinol Product Impurities

Molecules, 2022
Due to increased concerns regarding unidentified impurities in delta-8 tetrahydrocannabinol (Δ-8 THC) consumer products, a study using Nuclear Magnetic Resonance (NMR), high performance liquid chromatography (HPLC), and mass spectrometry (MS) was ...
Colleen Ray, C Michael Greenlief
exaly   +3 more sources

Risk Assessment of Over-the-Counter Cannabinoid-Based Cosmetics: Legal and Regulatory Issues Governing the Safety of Cannabinoid-Based Cosmetics in the UAE

Cosmetics, 2021
Purpose: The lack of scientific evidence of the safety and efficacy of over-the-counter topical cannabinoid-based cosmetics remains a concern. The current study attempted to assess the quality of cannabinoid-based cosmetic products available on the UAE ...
Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Baharudin Ibrahim, Mohamed Azmi Hassali, Sa’ed H. Zyoud   +5 more
doaj   +1 more source

Anticancer activity of Δ9-tetrahydrocannabinol and cannabinol in vitro and in human lung cancer xenograft

Asian Pacific Journal of Tropical Biomedicine, 2022
Objective: To investigate the effects of Δ9-tetrahydrocannabinol, the principal psychoactive compound of Cannabis sativa, and cannabinol, a Δ9-tetrahydrocannabinol degradative product, on human non-small cell lung cancer cells.
Surang Leelawat, Kawin Leelawat, Thaniya Wannakup, Worawan Saingam, Nanthaphong Khamthong, Fameera Madaka, Athip Maha, Patamaporn Pathompak, Lukman Sueree, Thanapat Songsak   +9 more
doaj   +1 more source

Identification of Potential Distinguishing Markers for the Use of Cannabis-Based Medicines or Street Cannabis in Serum Samples

Metabolites, 2021
Increasing prescription numbers of cannabis-based medicines raise the question of whether uptake of these medicines can be distinguished from recreational cannabis use. In this pilot study, serum cannabinoid profiles after use of cannabis-based medicines
Anne Scheunemann, Katrin Elsner, Tanja Germerott, Sergiu Groppa, Cornelius Hess, Isabelle Miederer, Alicia Poplawski, Jörg Röhrich   +7 more
doaj   +1 more source

Differences in Inhibitory Control and Resting Brain Metabolism between Older Chronic Users of Tetrahydrocannabinol (THC) or Cannabidiol (CBD)—A Pilot Study

Brain Sciences, 2022
Δ9-Tetrahydrocannabinol is the main psychoactive component of cannabis and cannabidiol is purportedly responsible for many of the medicinal benefits. The effects of Δ9-tetrahydrocannabinol and cannabidiol in younger populations have been well studied ...
Thorsten Rudroff, Craig D. Workman, Phillip E. Gander, Justin R. Deters, Laura L. Boles Ponto   +4 more
doaj   +1 more source

Cannabinoids for the control of experimental multiple sclerosis [PDF]

, 2010
PhDThere have been numerous studies reporting that cannabinoids, both exogenous and endogenous, have a potential beneficial function during incidences of neurological damage.
Pryce, Gareth
core   +4 more sources

Cannabinoids and Multiple Sclerosis: A Critical Analysis of Therapeutic Potentials and Safety Concerns

Pharmaceutics, 2023
Multiple sclerosis (MS) is a complicated condition in which the immune system attacks myelinated axons in the central nervous system (CNS), destroying both myelin and axons to varying degrees.
Roua A. Nouh, Ahmed Kamal, Anwar Abdelnaser   +2 more
doaj   +1 more source

A Proteomic View of Cellular and Molecular Effects of Cannabis

Biomolecules, 2021
Cannabis (Cannabis sativa), popularly known as marijuana, is the most commonly used psychoactive substance and is considered illicit in most countries worldwide.
Morteza Abyadeh, Vivek Gupta, Joao A. Paulo, Veer Gupta, Nitin Chitranshi, Angela Godinez, Danit Saks, Mafruha Hasan, Ardeshir Amirkhani, Matthew McKay, Ghasem H. Salekdeh, Paul A. Haynes, Stuart L. Graham, Mehdi Mirzaei   +13 more
doaj   +1 more source