Results 11 to 20 of about 20,460 (225)

Risk Assessment of Over-the-Counter Cannabinoid-Based Cosmetics: Legal and Regulatory Issues Governing the Safety of Cannabinoid-Based Cosmetics in the UAE

Cosmetics, 2021
Purpose: The lack of scientific evidence of the safety and efficacy of over-the-counter topical cannabinoid-based cosmetics remains a concern. The current study attempted to assess the quality of cannabinoid-based cosmetic products available on the UAE ...
Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Baharudin Ibrahim, Mohamed Azmi Hassali, Sa’ed H. Zyoud   +5 more
doaj   +1 more source

Anticancer activity of Δ9-tetrahydrocannabinol and cannabinol in vitro and in human lung cancer xenograft

Asian Pacific Journal of Tropical Biomedicine, 2022
Objective: To investigate the effects of Δ9-tetrahydrocannabinol, the principal psychoactive compound of Cannabis sativa, and cannabinol, a Δ9-tetrahydrocannabinol degradative product, on human non-small cell lung cancer cells.
Surang Leelawat, Kawin Leelawat, Thaniya Wannakup, Worawan Saingam, Nanthaphong Khamthong, Fameera Madaka, Athip Maha, Patamaporn Pathompak, Lukman Sueree, Thanapat Songsak   +9 more
doaj   +1 more source

Identification of Potential Distinguishing Markers for the Use of Cannabis-Based Medicines or Street Cannabis in Serum Samples

Metabolites, 2021
Increasing prescription numbers of cannabis-based medicines raise the question of whether uptake of these medicines can be distinguished from recreational cannabis use. In this pilot study, serum cannabinoid profiles after use of cannabis-based medicines
Anne Scheunemann, Katrin Elsner, Tanja Germerott, Sergiu Groppa, Cornelius Hess, Isabelle Miederer, Alicia Poplawski, Jörg Röhrich   +7 more
doaj   +1 more source

Differences in Inhibitory Control and Resting Brain Metabolism between Older Chronic Users of Tetrahydrocannabinol (THC) or Cannabidiol (CBD)—A Pilot Study

Brain Sciences, 2022
Δ9-Tetrahydrocannabinol is the main psychoactive component of cannabis and cannabidiol is purportedly responsible for many of the medicinal benefits. The effects of Δ9-tetrahydrocannabinol and cannabidiol in younger populations have been well studied ...
Thorsten Rudroff, Craig D. Workman, Phillip E. Gander, Justin R. Deters, Laura L. Boles Ponto   +4 more
doaj   +1 more source

Cannabinoids and Multiple Sclerosis: A Critical Analysis of Therapeutic Potentials and Safety Concerns

Pharmaceutics, 2023
Multiple sclerosis (MS) is a complicated condition in which the immune system attacks myelinated axons in the central nervous system (CNS), destroying both myelin and axons to varying degrees.
Roua A. Nouh, Ahmed Kamal, Anwar Abdelnaser   +2 more
doaj   +1 more source

A Proteomic View of Cellular and Molecular Effects of Cannabis

Biomolecules, 2021
Cannabis (Cannabis sativa), popularly known as marijuana, is the most commonly used psychoactive substance and is considered illicit in most countries worldwide.
Morteza Abyadeh, Vivek Gupta, Joao A. Paulo, Veer Gupta, Nitin Chitranshi, Angela Godinez, Danit Saks, Mafruha Hasan, Ardeshir Amirkhani, Matthew McKay, Ghasem H. Salekdeh, Paul A. Haynes, Stuart L. Graham, Mehdi Mirzaei   +13 more
doaj   +1 more source

The overview of existing knowledge on medical cannabis plants growing

Plant, Soil and Environment, 2021
The use of cannabis for medicinal purposes dates back well before the era of modern medicine, but in recent years research into the use of medical cannabis in the medical and pharmaceutical sciences has grown significantly.
Matěj Malík, Jiří Velechovský, Pavel Tlustoš   +2 more
doaj   +1 more source

Manipulation of THC Hair Concentrations by Commercially Available Products

Metabolites, 2022
Many drug tests are carried out by means of hair analysis. The aim of the present study was to clarify if and to what extent it is possible to manipulate the results of hair analyses on tetrahydrocannabinol (THC) by using various commercially available ...
Markus Bertges, Alexandra Ketikidou, Ralf Weiskirchen, Josef van Helden, Rudolf Boehnke, Cornelius Hess   +5 more
doaj   +1 more source

Combinations of Cannabidiol and Δ⁹-Tetrahydrocannabinol in Reducing Chemotherapeutic Induced Neuropathic Pain

Biomedicines, 2022
Neuropathic pain is a condition that impacts a substantial portion of the population and is expected to affect a larger percentage in the future. This type of pain is poorly managed by current therapies, including opioids and NSAIDS, and novel approaches
Diana E. Sepulveda, Kent E. Vrana, Nicholas M. Graziane, Wesley M. Raup-Konsavage   +3 more
doaj   +1 more source

Delta‐9‐tetrahydrocannabinol disrupts mitochondrial function and attenuates syncytialization in human placental BeWo cells

Physiological Reports, 2020
The psychoactive component in cannabis, delta‐9‐tetrahydrocannabinol, can restrict fetal growth and development. Delta‐9‐tetrahydrocannabinol has been shown to negatively impact cellular proliferation and target organelles like the mitochondria resulting
O’Llenecia S. Walker, Rehginald Ragos, Harmeet Gurm, Mariah Lapierre, Linda L. May, Sandeep Raha   +5 more
doaj   +1 more source