Results 61 to 70 of about 36,463 (268)

Evaluation of Therapeutic Opioids in Skin‐Derived Matrices (Sweat and Sebum) of Neonatal and Pediatric Patients and Their Role in Opioid Incorporation Into Hair

open access: yesDrug Testing and Analysis, EarlyView.
Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke   +7 more
wiley   +1 more source

Therapeutic potential of cannabinoids in neurological conditions: a systematic review of clinical trials

open access: yesFrontiers in Pharmacology
OverviewCannabinoids have gained increasing attention for their therapeutic potential in treating several neurological conditions, including neurodegenerative diseases, chronic pain, and epilepsy.
Alqassem Y. Hakami   +2 more
doaj   +1 more source

Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Regulate Intraocular Pressure

open access: yesInvestigative Ophthalmology and Visual Science, 2018
Purpose It has been known for nearly 50 years that cannabis and the psychoactive constituent Δ9-tetrahydrocannabinol (THC) reduce intraocular pressure (IOP).
Sally Miller   +4 more
semanticscholar   +1 more source

Combustion of Waste Rapeseed Oil and Jet Propellant‐8 Blends in a CI Engine

open access: yesEnergy Science &Engineering, EarlyView.
Using waste rapeseed oil (WRO) mixed with Jet Propellant‐8 (JP‐8) as fuel for a compression ignition engine. ABSTRACT The study examines the potential of blending waste rapeseed oil (WRO) with Jet Propellant‐8 (JP‐8) as a fuel for compression ignition (CI) engines.
Grzegorz Pawlak   +6 more
wiley   +1 more source

Δ9-Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits

open access: yesTranslational Vision Science & Technology, 2019
Purpose Δ9-Tetrahydrocannabinol-valine-hemisuccinate, a hydrophilic prodrug of Δ9-tetrahydrocannabinol, synthesized with the aim of improving the ocular bioavailability of the parent molecule, was investigated in a lipid-based nanoparticle dosage form ...
Pranjal Taskar   +7 more
semanticscholar   +1 more source

Is Delta-9-Tetrahydrocannabinol Estrogenic? [PDF]

open access: yesScience, 1977
Evidence is presented which indicates the lack of effect of delta-9-tetrahydrocannabinol or cannabis resin on tritiated estradiol-17beta binding to uterine cytosol receptor. The cannabinoids which demasculinize when given in vivo had no estrogneic properties as assessed by receptor studies on 2 different rodent species.
A B, Okey, G P, Bondy
openaire   +2 more sources

Potential of solid‐state microwaves in lab‐scale chemical‐process development

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The integration of a solid‐state microwave (MW) generator into a newly designed, versatile MW reactor ensures improved energy efficiency, precise process control and broader application potential. In its most particular feature, the device supports the modification of dielectric‐radiation orientation and can be operated under ...
Christian Cravotto   +4 more
wiley   +1 more source

Cannabis and Autoimmunity: Possible Mechanisms of Action

open access: yesImmunoTargets and Therapy, 2021
Valeria Giorgi1 1, Daniela Marotto2 2, Alberto Batticciotto3 3, Fabiola Atzeni4 4, Sara Bongiovanni1 1, Piercarlo Sarzi-Puttini1 1 1Rheumatology Unit, Internal Medicine Department, ASST Fatebenefratelli-Sacco, Milan University School of Medicine, Milan ...
Giorgi V   +5 more
doaj  

Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav   +3 more
wiley   +1 more source

Optimal condition of cannabis maceration to obtain the high cannabidiol and Δ9-tetrahydrocannabinol content.

open access: yesAnais da Academia Brasileira de Ciências, 2019
The aim of this work was to optimize a maceration condition of cannabis (Cannabis sativa L.). A circumscribed central composite experimental design was applied in this work. Temperature and time were varied from 40-80 °C and 30-90 min, respectively.
C. Monton   +5 more
semanticscholar   +1 more source

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