Results 61 to 70 of about 48,054 (298)

Cannabis and Autoimmunity: Possible Mechanisms of Action

ImmunoTargets and Therapy, 2021
Valeria Giorgi1 1, Daniela Marotto2 2, Alberto Batticciotto3 3, Fabiola Atzeni4 4, Sara Bongiovanni1 1, Piercarlo Sarzi-Puttini1 1 1Rheumatology Unit, Internal Medicine Department, ASST Fatebenefratelli-Sacco, Milan University School of Medicine, Milan ...
Giorgi V, Marotto D, Batticciotto A, Atzeni F, Bongiovanni S, Sarzi-Puttini P   +5 more
doaj  

Cannabinoid Activity—Is There a Causal Connection to Spasmolysis in Clinical Studies?

Biomolecules, 2021
Cannabinoid drugs are registered for postoperative nausea and emesis, Tourette syndrome and tumor-related anorexia, but are also used for spasticity and pain relief, among other conditions.
Daniel Joseph, Johannes Schulze
doaj   +1 more source

Medical use of cannabis: italian and european legislation [PDF]

, 2018
This review illustrates some brief considerations of the medical use of cannabis recently issued in Italy. History and uses of cannabis throughout centuries and different countries are illustrated together with a description of botany and active ...
Di Luca, A., Di Luca, N. M., Montanari Vergallo, G., Zaami, S.   +3 more
core   +1 more source

(2‐Phosphinophenyl)aluminum Dichloride Complexes as Intramolecular Al/P Frustrated Lewis Pairs for Ketone, Ester, and Imine Activation

Chemistry – A European Journal, EarlyView.
Three 2‐phosphinophenylaluminum dichloride complexes were synthesized and characterized as novel intramolecular FLPs. These FLP systems exhibit high Lewis acidity and effectively activate challenging substrates including aliphatic ketones, imines, and esters. DFT analysis revealed that strain release and Al–P dynamics govern their reactivity. Abstract (
Yoshihiro Nishimoto, Hirotaka Okamoto, Makoto Yasuda   +2 more
wiley   +1 more source

Safety of cannabidiol products as a social issue: A case series

Acute Medicine & Surgery
Background Cannabidiol (CBD) products have increased in popularity in Japan in recent years, particularly among young people. Some CBD products contain tetrahydrocannabinol (THC), the main ingredient of cannabis, and its analogs, which are illegal in ...
Yukari Maki, Asuka Tsuchiya, Rie Yamamoto, Takeshi Saito, Seiji Morita, Yoshihide Nakagawa   +5 more
doaj   +1 more source

Cannabis as a Source of Approved Drugs: A New Look at an Old Problem

Molecules, 2023
Cannabis plants have been used in medicine since ancient times. They are well known for their anti-diabetic, anti-inflammatory, neuroprotective, anti-cancer, anti-oxidative, anti-microbial, anti-viral, and anti-fungal activities.
Adi Gabarin, Ludmila Yarmolinsky, Arie Budovsky, Boris Khalfin, Shimon Ben-Shabat   +4 more
doaj   +1 more source

Correlation between blood and oral fluid psychoactive drug concentrations and cognitive impairment in driving under the influence of drugs [PDF]

, 2017
The effects of drugs on driving performance should be checked with drug concentration in the brain and at the same time with the evaluation of both the behavioural and neurophysiological effects. The best accessible indicator of this information is the
Busardò, Francesco Paolo, Faro, Alfredo Fabrizio Lo, Graziano, Silvia, Montana, Angelo, Pellegrini, Manuela, Pichini, Simona, Zaami, Simona   +6 more
core   +1 more source

The impact of recreational cannabinoid legalization on utilization in a pregnant population

Frontiers in Public Health
BackgroundMarijuana potency and utilization both continue to increase across the United States. While the overall prevalence of cannabinoid utilization during pregnancy has been surveyed in various studies, the direct impact of changing governmental ...
Jacob Torres, Colton Miller, Michael Apostol, Jessica Gross, Jessie R. Maxwell, Jessie R. Maxwell   +5 more
doaj   +1 more source

Prescription Practices of Cannabinoids in Children with Cerebral Palsy Worldwide—A Survey of the Swiss Cerebral Palsy Registry

Children, 2023
Cannabinoids are prescribed to children with cerebral palsy despite limited evidence. We aimed to assess cannabinoid prescribing practices in children with cerebral palsy, focusing on indications, types of preparations used, and tolerability. Furthermore,
Sandra Hunziker, Federico Morosoli, Kathrin Zuercher, Anne Tscherter, Sebastian Grunt   +4 more
doaj   +1 more source

Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults

Clinical Pharmacology &Therapeutics, EarlyView.
Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo, Donna A. Volpe, Anik Chaturbedi, Aanchal Shah, Ashok Krishna, Paula L Hyland, Giri Vegesna, Cheng‐Hui Hsiao, Ryan De Palma, Melanie Fein, Rodney Rouse, Jeffry Florian   +11 more
wiley   +1 more source