Results 41 to 50 of about 4,486 (199)
Visible-Light Photoredox Catalysis in Flow [PDF]
, 2012 Photoredox catalysis: A variety of organic transformations mediated by visible-light-active photoredox catalysts have been conducted in a photochemical flow reactor.
Andrews +51 more
core +1 more source
Contra-thermodynamic hydrogen atom abstraction in the selective C−H functionalization of trialkylamine N‑CH3 groups [PDF]
, 2016 We report a simple one-pot protocol that affords functionalization of N-CH3 groups in N-methyl-N,N-dialkylamines with high selectivity over N-CH2R or N-CHR2 groups.
Barham, Joshua P. +2 more
core +1 more source
Molecules, 2022 A mild and efficient strategy for the synthesis of tricyclic 1,2,4-oxadiazolines-fused tetrahydro-isoquinolines derivatives via [3 + 2] cycloaddition reaction is reported.
Kaikai Wang +6 more
doaj +1 more source
A novel method for the synthesis of 1-aryltetrahydroisoquinolines [PDF]
, 2017 Carbenium ions generated from substituted benzhydryls using acid catalysis undergo smooth intramolecular trapping by pendant sulfonamide groups to provide excellent yields of 1 ...
Abdel-Fattah, Hanan A. +5 more
core +2 more sources
Molecules, 2018 A mild and highly efficient metal-free oxidative α-cyanation of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) has been accomplished at an ambient temperature via DDQ oxidation and subsequent trapping of N-acyl/sulfonyl iminium ions with (n-
Hong Pyo Kim +4 more
doaj +1 more source
Synthesis of bioactive compounds. Studies of their attachment to nanoparticles [PDF]
, 2017 The 1-aryl tetrahydroisoquinolines have attracted great attention in medicinal chemistry due to their biological activity. These compounds present antitumor, anti-HIV and antibacterial activities.
Díaz, Amelia +4 more
core
Palladium-catalyzed selective α-arylation of ortho -bromoacetophenones [PDF]
, 2014 Synthesis of 1-(2-bromophenyl)-2-phenylethanones via an intermolecular Pd-catalyzed α-arylation of 1-(2-bromophenyl)ethanones is presented. The method relies on selective C-H activation (α-arylation) of relatively more reactive external iodo-arenes as ...
A, Gopi Krishna Reddy +2 more
core +1 more source
Molecules, 2018 A simple procedure for the synthesis of 8-fluoro-3,4-dihydroisoquinoline is described below, based on a directed ortho-lithiation reaction. This key intermediate was then applied in various transformations.
Csilla Hargitai +4 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2020 A ruthenium-catalyzed photoredox coupling of substituted N-aryltetrahydroisoquinolines (THIQs) and different bench-stable pyridinium salts was successfully developed to give fast access to 1-benzyl-THIQs.
David Schönbauer +3 more
doaj +1 more source
Plasmin Regulation through Allosteric, Sulfated, Small Molecules [PDF]
, 2015 Plasmin, a key serine protease, plays a major role in clot lysis and extracellular matrix remodeling. Heparin, a natural polydisperse sulfated glycosaminoglycan, is known to allosterically modulate plasmin activity.
Al-Horani, Rami A. +3 more
core +3 more sources