Results 91 to 100 of about 4,966 (204)

Structure-Based Design of Acetolactate Synthase From Bacillus licheniformis Improved Protein Stability Under Acidic Conditions

open access: yesFrontiers in Microbiology, 2020
Catabolic acetolactate synthase (cALS) plays a crucial role in the quality of liquor because of its ability to catalyze the synthesis of the endogenous precursor product α-acetolactate of the aromatic compound tetramethylpyrazine (TTMP) and acetoin ...
Ting Zhao   +8 more
doaj   +1 more source

Antimicrobial activity of pyrazine and quinoxaline N,N’-dioxide heterocyclic compounds [PDF]

open access: yes, 2007
The nitrogen heterocyclic organic compounds 1,4 dioxide pyrazine and quinoxaline derivatives have been widely studied due to their potential use as synthetic drugs.
Fernandes, Rúben   +5 more
core  

Pollinators, “mustard oil” volatiles, and fruit production in flowers of the dioecious tree Drypetes natalensis (Putranjivaceae) [PDF]

open access: yes, 2009
The Putranjivaceae is an enigmatic family, notable for being the only lineage outside the Capparales to possess the glucosinolate biochemical pathway, which forms the basis of an induced chemical defense system against herbivores (the “ mustard oil bomb ”
Griffiths, M E   +3 more
core   +2 more sources

Taohong Siwu Decoction Regulates MSC‐Mediated H‐Type Angiogenesis to Accelerate Bone Fracture Healing Through VHL/HIF‐1α Ubiquitination

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Bone fracture healing is a multifaceted process that involves different stages and intercellular interactions. In this study, we aimed to investigate the effect of Taohong Siwu decoction (TSD) on bone fracture healing and the underlying mechanisms.
Wangyang Li   +9 more
wiley   +1 more source

MYB Activates the Hedgehog Signaling Pathway to Repress Natural Killer Cytotoxicity in Cervical Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 41, Issue 12, December 2025.
ABSTRACT Natural killer (NK) cells present in the tumor microenvironment serve as a critical line of defense against various malignancies, including cervical cancer. While MYB is known to drive malignancy progression, its influence on NK cell activity remains poorly understood.
Yu Wang, Chen Li
wiley   +1 more source

The aflatoxin B1-fumonisin B1 toxicity in BRL-3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism [PDF]

open access: yes, 2017
Human oral exposure to aflatoxin B1 (AFB1) and fumonisin B1 (FB1) is associated with increased hepatocellular carcinoma. Although evidence suggested interactive AFB1–FB1 hepatotoxicity, the underlying mechanisms remain mostly unidentified.
Arias, Silvina Lorena   +5 more
core   +1 more source

Alkaline–Acid Intestine Environment Controlled by A Carbonic Anhydrase Gene Influences Synthesis of Sex Pheromone by Symbionts

open access: yesAdvanced Science, Volume 12, Issue 43, November 20, 2025.
A model proposing that elevated rectal expression of CAh1 in males alkalinizes the environment to regulate Bacillus production of a male‐specific sex pheromone. Abstract The intricate interplay between animals and their intestinal microbes is pivotal in shaping various aspects of animal biology.
Shiyu Gui   +9 more
wiley   +1 more source

Dexamethasone Down-regulates Osteocalcin in Bone Cells through Leptin Pathway [PDF]

open access: yes, 2018
Glucocorticoid therapy, especially at higher doses, is associated with significantadverse side effects including osteoporosis. Leptin, secreted from adipose tissue, has diverse effects on bone tissue regulation.
Chen, Shu-Mei   +5 more
core   +1 more source

Biocompatible Mesoporous Materials for Bone Therapy

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
Biocompatible mesoporous materials (BMMs), characterized by high specific surface area, tunable pore size, different shapes and structures, and multidimensional functionalized modifications, have revolutionary applications in treating bone‐related diseases.
Biao Yu   +6 more
wiley   +1 more source

Effect of Roasting Temperature and Time on Precursors, Volatile Components and Flavour Quality of Cocoa Beans During Nib Roasting [PDF]

open access: yes, 1997
The effect of roasting temperature and time on precursors, volatile components and quality of cocoa beans during nib roasting was studied using response surface methodology (RSM) which consisted two independent variables of temperature (110-170˚C) and ...
Wan Ishak @ Wan Ahmad, Wan Rosli
core  

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